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A genome-wide association study follow-up suggests a possible role for PPARG in systemic sclerosis susceptibility.
López-Isac E, Bossini-Castillo L, Simeon CP, Egurbide MV, Alegre-Sancho JJ, Callejas JL, Roman-Ivorra JA, Freire M, Beretta L, Santaniello A, Airó P, Lunardi C, Hunzelmann N, Riemekasten G, Witte T, Kreuter A, Distler JH, Schuerwegh AJ, Vonk MC, Voskuyl AE, Shiels PG, van Laar JM, Fonseca C, Denton C, Herrick A, Worthington J, Assassi S, Koeleman BP, Mayes MD, Radstake TR, Martin J; Spanish Scleroderma Group. López-Isac E, et al. Among authors: callejas jl. Arthritis Res Ther. 2014 Jan 9;16(1):R6. doi: 10.1186/ar4432. Arthritis Res Ther. 2014. PMID: 24401602 Free PMC article.
Fine-mapping and transethnic genotyping establish IL2/IL21 genetic association with lupus and localize this genetic effect to IL21.
Hughes T, Kim-Howard X, Kelly JA, Kaufman KM, Langefeld CD, Ziegler J, Sanchez E, Kimberly RP, Edberg JC, Ramsey-Goldman R, Petri M, Reveille JD, Martín J, Brown EE, Vilá LM, Alarcón GS, James JA, Gilkeson GS, Moser KL, Gaffney PM, Merrill JT, Vyse TJ, Alarcón-Riquelme ME; BIOLUPUS Network; Nath SK, Harley JB, Sawalha AH. Hughes T, et al. Arthritis Rheum. 2011 Jun;63(6):1689-97. doi: 10.1002/art.30320. Arthritis Rheum. 2011. PMID: 21425124 Free PMC article.
A GWAS follow-up study reveals the association of the IL12RB2 gene with systemic sclerosis in Caucasian populations.
Bossini-Castillo L, Martin JE, Broen J, Gorlova O, Simeón CP, Beretta L, Vonk MC, Callejas JL, Castellví I, Carreira P, García-Hernández FJ, Fernández Castro M; Spanish Scleroderma Group; Coenen MJ, Riemekasten G, Witte T, Hunzelmann N, Kreuter A, Distler JH, Koeleman BP, Voskuyl AE, Schuerwegh AJ, Palm Ø, Hesselstrand R, Nordin A, Airó P, Lunardi C, Scorza R, Shiels P, van Laar JM, Herrick A, Worthington J, Denton C, Tan FK, Arnett FC, Agarwal SK, Assassi S, Fonseca C, Mayes MD, Radstake TR, Martin J. Bossini-Castillo L, et al. Among authors: callejas jl. Hum Mol Genet. 2012 Feb 15;21(4):926-33. doi: 10.1093/hmg/ddr522. Epub 2011 Nov 10. Hum Mol Genet. 2012. PMID: 22076442 Free PMC article.
Analysis of autosomal genes reveals gene-sex interactions and higher total genetic risk in men with systemic lupus erythematosus.
Hughes T, Adler A, Merrill JT, Kelly JA, Kaufman KM, Williams A, Langefeld CD, Gilkeson GS, Sanchez E, Martin J, Boackle SA, Stevens AM, Alarcón GS, Niewold TB, Brown EE, Kimberly RP, Edberg JC, Ramsey-Goldman R, Petri M, Reveille JD, Criswell LA, Vilá LM, Jacob CO, Gaffney PM, Moser KL, Vyse TJ, Alarcón-Riquelme ME; BIOLUPUS Network; James JA, Tsao BP, Scofield RH, Harley JB, Richardson BC, Sawalha AH. Hughes T, et al. Ann Rheum Dis. 2012 May;71(5):694-9. doi: 10.1136/annrheumdis-2011-200385. Epub 2011 Nov 21. Ann Rheum Dis. 2012. PMID: 22110124 Free PMC article.
A multicenter study confirms CD226 gene association with systemic sclerosis-related pulmonary fibrosis.
Bossini-Castillo L, Simeon CP, Beretta L, Broen JC, Vonk MC, Ríos-Fernández R, Espinosa G, Carreira P, Camps MT, Castillo MJ, González-Gay MA, Beltrán E, Carmen Freire Md, Narváez J, Tolosa C, Witte T, Kreuter A, Schuerwegh AJ, Hoffmann-Vold AM, Hesselstrand R, Lunardi C, van Laar JM, Chee MM, Herrick A, Koeleman BP, Denton CP, Fonseca C, Radstake TR, Martin J; Spanish Scleroderma Group. Bossini-Castillo L, et al. Arthritis Res Ther. 2012 Apr 24;14(2):R85. doi: 10.1186/ar3809. Arthritis Res Ther. 2012. PMID: 22531499 Free PMC article.
Evaluation of a shared autoimmune disease-associated polymorphism of TRAF6 in systemic sclerosis and giant cell arteritis.
Carmona FD, Serrano A, Rodríguez-Rodríguez L, Callejas JL, Simeón CP, Carreira P, Castañeda S, Solans R, Blanco R; Spanish Scleroderma Group; Spanish Giant Cell Arteritis Group; González-Gay MA, Martín J. Carmona FD, et al. Among authors: callejas jl. J Rheumatol. 2012 Jun;39(6):1275-9. doi: 10.3899/jrheum.120038. Epub 2012 May 15. J Rheumatol. 2012. PMID: 22589256
Analysis of the association between CD40 and CD40 ligand polymorphisms and systemic sclerosis.
Teruel M, Simeon CP, Broen J, Vonk MC, Carreira P, Camps MT, García-Portales R, Delgado-Frías E, Gallego M, Espinosa G; Spanish Scleroderma Group; Beretta L, Airó P, Lunardi C, Riemekasten G, Witte T, Krieg T, Kreuter A, Distler JH, Hunzelmann N, Koeleman BP, Voskuyl AE, Schuerwegh AJ, González-Gay MA, Radstake TR, Martin J. Teruel M, et al. Arthritis Res Ther. 2012 Jun 25;14(3):R154. doi: 10.1186/ar3890. Arthritis Res Ther. 2012. PMID: 22731751 Free PMC article.
Implication of IL-2/IL-21 region in systemic sclerosis genetic susceptibility.
Diaz-Gallo LM, Simeon CP, Broen JC, Ortego-Centeno N, Beretta L, Vonk MC, Carreira PE, Vargas S, Román-Ivorra JA, González-Gay MA, Tolosa C, López-Longo FJ, Espinosa G, Vicente EF, Hesselstrand R, Riemekasten G, Witte T, Distler JH, Voskuyl AE, Schuerwegh AJ, Shiels PG, Nordin A, Padyukov L, Hoffmann-Vold AM, Scorza R, Lunardi C, Airo P, van Laar JM, Hunzelmann N, Gathof BS, Kreuter A, Herrick A, Worthington J, Denton CP, Zhou X, Arnett FC, Fonseca C, Koeleman BP, Assasi S, Radstake TR, Mayes MD, Martín J; Spanish Scleroderma Group. Diaz-Gallo LM, et al. Ann Rheum Dis. 2013 Jul;72(7):1233-8. doi: 10.1136/annrheumdis-2012-202357. Epub 2012 Nov 21. Ann Rheum Dis. 2013. PMID: 23172754 Free PMC article.
KCNA5 gene is not confirmed as a systemic sclerosis-related pulmonary arterial hypertension genetic susceptibility factor.
Bossini-Castillo L, Simeon CP, Beretta L, Broen J, Vonk MC, Callejas JL, Carreira P, Rodríguez-Rodríguez L, García-Portales R, González-Gay MA, Castellví I, Camps MT, Tolosa C, Vicente-Rabaneda E, Egurbide MV; Spanish Scleroderma Group; Schuerwegh AJ, Hesselstrand R, Lunardi C, van Laar JM, Shiels P, Herrick A, Worthington J, Denton C, Radstake TR, Fonseca C, Martin J. Bossini-Castillo L, et al. Among authors: callejas jl. Arthritis Res Ther. 2012 Dec 27;14(6):R273. doi: 10.1186/ar4124. Arthritis Res Ther. 2012. PMID: 23270786 Free PMC article.
The systemic lupus erythematosus IRF5 risk haplotype is associated with systemic sclerosis.
Carmona FD, Martin JE, Beretta L, Simeón CP, Carreira PE, Callejas JL, Fernández-Castro M, Sáez-Comet L, Beltrán E, Camps MT, Egurbide MV; Spanish Scleroderma Group; Airó P, Scorza R, Lunardi C, Hunzelmann N, Riemekasten G, Witte T, Kreuter A, Distler JH, Madhok R, Shiels P, van Laar JM, Fonseca C, Denton C, Herrick A, Worthington J, Schuerwegh AJ, Vonk MC, Voskuyl AE, Radstake TR, Martín J. Carmona FD, et al. Among authors: callejas jl. PLoS One. 2013;8(1):e54419. doi: 10.1371/journal.pone.0054419. Epub 2013 Jan 23. PLoS One. 2013. PMID: 23372721 Free PMC article.
88 results