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PI3KCA plays a major role in multiple myeloma and its inhibition with BYL719 decreases proliferation, synergizes with other therapies and overcomes stroma-induced resistance.
Azab F, Vali S, Abraham J, Potter N, Muz B, de la Puente P, Fiala M, Paasch J, Sultana Z, Tyagi A, Abbasi T, Vij R, Azab AK. Azab F, et al. Among authors: abbasi t. Br J Haematol. 2014 Apr;165(1):89-101. doi: 10.1111/bjh.12734. Epub 2014 Jan 9. Br J Haematol. 2014. PMID: 24405121 Free article.
Personalization of cancer treatment using predictive simulation.
Doudican NA, Kumar A, Singh NK, Nair PR, Lala DA, Basu K, Talawdekar AA, Sultana Z, Tiwari KK, Tyagi A, Abbasi T, Vali S, Vij R, Fiala M, King J, Perle M, Mazumder A. Doudican NA, et al. Among authors: abbasi t. J Transl Med. 2015 Feb 1;13:43. doi: 10.1186/s12967-015-0399-y. J Transl Med. 2015. PMID: 25638213 Free PMC article.
Celastrol inhibits proliferation and induces chemosensitization through down-regulation of NF-κB and STAT3 regulated gene products in multiple myeloma cells.
Kannaiyan R, Hay HS, Rajendran P, Li F, Shanmugam MK, Vali S, Abbasi T, Kapoor S, Sharma A, Kumar AP, Chng WJ, Sethi G. Kannaiyan R, et al. Among authors: abbasi t. Br J Pharmacol. 2011 Nov;164(5):1506-21. doi: 10.1111/j.1476-5381.2011.01449.x. Br J Pharmacol. 2011. PMID: 21506956 Free PMC article.
In vitro and in vivo anticancer effects of mevalonate pathway modulation on human cancer cells.
Jiang P, Mukthavaram R, Chao Y, Nomura N, Bharati IS, Fogal V, Pastorino S, Teng D, Cong X, Pingle SC, Kapoor S, Shetty K, Aggrawal A, Vali S, Abbasi T, Chien S, Kesari S. Jiang P, et al. Among authors: abbasi t. Br J Cancer. 2014 Oct 14;111(8):1562-71. doi: 10.1038/bjc.2014.431. Epub 2014 Aug 5. Br J Cancer. 2014. PMID: 25093497 Free PMC article.
In silico modeling predicts drug sensitivity of patient-derived cancer cells.
Pingle SC, Sultana Z, Pastorino S, Jiang P, Mukthavaram R, Chao Y, Bharati IS, Nomura N, Makale M, Abbasi T, Kapoor S, Kumar A, Usmani S, Agrawal A, Vali S, Kesari S. Pingle SC, et al. Among authors: abbasi t. J Transl Med. 2014 May 21;12:128. doi: 10.1186/1479-5876-12-128. J Transl Med. 2014. PMID: 24884660 Free PMC article.
132 results