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Page 1
Discovery of MK-1439, an orally bioavailable non-nucleoside reverse transcriptase inhibitor potent against a wide range of resistant mutant HIV viruses.
Côté B, Burch JD, Asante-Appiah E, Bayly C, Bédard L, Blouin M, Campeau LC, Cauchon E, Chan M, Chefson A, Coulombe N, Cromlish W, Debnath S, Deschênes D, Dupont-Gaudet K, Falgueyret JP, Forget R, Gagné S, Gauvreau D, Girardin M, Guiral S, Langlois E, Li CS, Nguyen N, Papp R, Plamondon S, Roy A, Roy S, Seliniotakis R, St-Onge M, Ouellet S, Tawa P, Truchon JF, Vacca J, Wrona M, Yan Y, Ducharme Y. Côté B, et al. Among authors: coulombe n. Bioorg Med Chem Lett. 2014 Feb 1;24(3):917-22. doi: 10.1016/j.bmcl.2013.12.070. Epub 2013 Dec 24. Bioorg Med Chem Lett. 2014. PMID: 24412110
Identification of a GABAB receptor subunit, gb2, required for functional GABAB receptor activity.
Ng GY, Clark J, Coulombe N, Ethier N, Hebert TE, Sullivan R, Kargman S, Chateauneuf A, Tsukamoto N, McDonald T, Whiting P, Mezey E, Johnson MP, Liu Q, Kolakowski LF Jr, Evans JF, Bonner TI, O'Neill GP. Ng GY, et al. Among authors: coulombe n. J Biol Chem. 1999 Mar 19;274(12):7607-10. doi: 10.1074/jbc.274.12.7607. J Biol Chem. 1999. PMID: 10075644 Free article.
Discovery of a receptor related to the galanin receptors.
Lee DK, Nguyen T, O'Neill GP, Cheng R, Liu Y, Howard AD, Coulombe N, Tan CP, Tang-Nguyen AT, George SR, O'Dowd BF. Lee DK, et al. Among authors: coulombe n. FEBS Lett. 1999 Mar 5;446(1):103-7. doi: 10.1016/s0014-5793(99)00009-5. FEBS Lett. 1999. PMID: 10100623 Free article.
Differential efficacy of caspase inhibitors on apoptosis markers during sepsis in rats and implication for fractional inhibition requirements for therapeutics.
Méthot N, Huang J, Coulombe N, Vaillancourt JP, Rasper D, Tam J, Han Y, Colucci J, Zamboni R, Xanthoudakis S, Toulmond S, Nicholson DW, Roy S. Méthot N, et al. Among authors: coulombe n. J Exp Med. 2004 Jan 19;199(2):199-207. doi: 10.1084/jem.20031791. Epub 2004 Jan 12. J Exp Med. 2004. PMID: 14718517 Free PMC article.
Cloning of a novel G-protein-coupled receptor GPR 51 resembling GABAB receptors expressed predominantly in nervous tissues and mapped proximal to the hereditary sensory neuropathy type 1 locus on chromosome 9.
Ng GY, McDonald T, Bonnert T, Rigby M, Heavens R, Whiting P, Chateauneuf A, Coulombe N, Kargman S, Caskey T, Evans J, O'neill GP, Liu Q. Ng GY, et al. Among authors: coulombe n. Genomics. 1999 Mar 15;56(3):288-95. doi: 10.1006/geno.1998.5706. Genomics. 1999. PMID: 10087195
Coexpression of full-length gamma-aminobutyric acid(B) (GABA(B)) receptors with truncated receptors and metabotropic glutamate receptor 4 supports the GABA(B) heterodimer as the functional receptor.
Sullivan R, Chateauneuf A, Coulombe N, Kolakowski LF Jr, Johnson MP, Hebert TE, Ethier N, Belley M, Metters K, Abramovitz M, O'Neill GP, Ng GY. Sullivan R, et al. Among authors: coulombe n. J Pharmacol Exp Ther. 2000 May;293(2):460-7. J Pharmacol Exp Ther. 2000. PMID: 10773016
Characterization of the human cysteinyl leukotriene 2 receptor.
Heise CE, O'Dowd BF, Figueroa DJ, Sawyer N, Nguyen T, Im DS, Stocco R, Bellefeuille JN, Abramovitz M, Cheng R, Williams DL Jr, Zeng Z, Liu Q, Ma L, Clements MK, Coulombe N, Liu Y, Austin CP, George SR, O'Neill GP, Metters KM, Lynch KR, Evans JF. Heise CE, et al. Among authors: coulombe n. J Biol Chem. 2000 Sep 29;275(39):30531-6. doi: 10.1074/jbc.M003490200. J Biol Chem. 2000. PMID: 10851239 Free article.
Molecular characterization and expression of cloned human galanin receptors GALR2 and GALR3.
Kolakowski LF Jr, O'Neill GP, Howard AD, Broussard SR, Sullivan KA, Feighner SD, Sawzdargo M, Nguyen T, Kargman S, Shiao LL, Hreniuk DL, Tan CP, Evans J, Abramovitz M, Chateauneuf A, Coulombe N, Ng G, Johnson MP, Tharian A, Khoshbouei H, George SR, Smith RG, O'Dowd BF. Kolakowski LF Jr, et al. Among authors: coulombe n. J Neurochem. 1998 Dec;71(6):2239-51. doi: 10.1046/j.1471-4159.1998.71062239.x. J Neurochem. 1998. PMID: 9832121 Free article.
Characterization of the human cysteinyl leukotriene CysLT1 receptor.
Lynch KR, O'Neill GP, Liu Q, Im DS, Sawyer N, Metters KM, Coulombe N, Abramovitz M, Figueroa DJ, Zeng Z, Connolly BM, Bai C, Austin CP, Chateauneuf A, Stocco R, Greig GM, Kargman S, Hooks SB, Hosfield E, Williams DL Jr, Ford-Hutchinson AW, Caskey CT, Evans JF. Lynch KR, et al. Among authors: coulombe n. Nature. 1999 Jun 24;399(6738):789-93. doi: 10.1038/21658. Nature. 1999. PMID: 10391245
30 results