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Discovery of MK-1439, an orally bioavailable non-nucleoside reverse transcriptase inhibitor potent against a wide range of resistant mutant HIV viruses.
Bioorg Med Chem Lett. 2014 Feb 1;24(3):917-22. doi: 10.1016/j.bmcl.2013.12.070. Epub 2013 Dec 24.
Bioorg Med Chem Lett. 2014.
PMID: 24412110
Cu-catalyzed N-arylation of oxazolidinones: an efficient synthesis of the kappa-opioid receptor Agonist CJ-15161.
Ghosh A, Sieser JE, Caron S, Couturier M, Dupont-Gaudet K, Girardin M.
Ghosh A, et al. Among authors: dupont gaudet k.
J Org Chem. 2006 Feb 3;71(3):1258-61. doi: 10.1021/jo052060z.
J Org Chem. 2006.
PMID: 16438550
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Phosphine-mediated [4 + 2] annulation of bis(enones): a Lewis base catalyzed "mock Diels-Alder" reaction.
Couturier M, Ménard F, Ragan JA, Riou M, Dauphin E, Andresen BM, Ghosh A, Dupont-Gaudet K, Girardin M.
Couturier M, et al. Among authors: dupont gaudet k.
Org Lett. 2004 May 27;6(11):1857-60. doi: 10.1021/ol049392v.
Org Lett. 2004.
PMID: 15151432
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Inter- and intramolecular [4 + 1]-cycloadditions between electron-poor dienes and electron-rich carbenes.
Spino C, Rezaei H, Dupont-Gaudet K, Bélanger F.
Spino C, et al. Among authors: dupont gaudet k.
J Am Chem Soc. 2004 Aug 18;126(32):9926-7. doi: 10.1021/ja046344x.
J Am Chem Soc. 2004.
PMID: 15303859
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