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RAG-mediated recombination is the predominant driver of oncogenic rearrangement in ETV6-RUNX1 acute lymphoblastic leukemia.
Papaemmanuil E, Rapado I, Li Y, Potter NE, Wedge DC, Tubio J, Alexandrov LB, Van Loo P, Cooke SL, Marshall J, Martincorena I, Hinton J, Gundem G, van Delft FW, Nik-Zainal S, Jones DR, Ramakrishna M, Titley I, Stebbings L, Leroy C, Menzies A, Gamble J, Robinson B, Mudie L, Raine K, O'Meara S, Teague JW, Butler AP, Cazzaniga G, Biondi A, Zuna J, Kempski H, Muschen M, Ford AM, Stratton MR, Greaves M, Campbell PJ. Papaemmanuil E, et al. Among authors: van loo p, van delft fw. Nat Genet. 2014 Feb;46(2):116-25. doi: 10.1038/ng.2874. Epub 2014 Jan 12. Nat Genet. 2014. PMID: 24413735 Free PMC article.
Prospective gene expression analysis accurately subtypes acute leukaemia in children and establishes a commonality between hyperdiploidy and t(12;21) in acute lymphoblastic leukaemia.
van Delft FW, Bellotti T, Luo Z, Jones LK, Patel N, Yiannikouris O, Hill AS, Hubank M, Kempski H, Fletcher D, Chaplin T, Foot N, Young BD, Hann IM, Gammerman A, Saha V. van Delft FW, et al. Br J Haematol. 2005 Jul;130(1):26-35. doi: 10.1111/j.1365-2141.2005.05545.x. Br J Haematol. 2005. PMID: 15982341 Free article.
Immunologically silent cancer clone transmission from mother to offspring.
Isoda T, Ford AM, Tomizawa D, van Delft FW, De Castro DG, Mitsuiki N, Score J, Taki T, Morio T, Takagi M, Saji H, Greaves M, Mizutani S. Isoda T, et al. Among authors: van delft fw. Proc Natl Acad Sci U S A. 2009 Oct 20;106(42):17882-5. doi: 10.1073/pnas.0904658106. Epub 2009 Oct 12. Proc Natl Acad Sci U S A. 2009. PMID: 19822752 Free PMC article.
Genetic variegation of clonal architecture and propagating cells in leukaemia.
Anderson K, Lutz C, van Delft FW, Bateman CM, Guo Y, Colman SM, Kempski H, Moorman AV, Titley I, Swansbury J, Kearney L, Enver T, Greaves M. Anderson K, et al. Among authors: van delft fw. Nature. 2011 Jan 20;469(7330):356-61. doi: 10.1038/nature09650. Epub 2010 Dec 15. Nature. 2011. PMID: 21160474
Clonal origins of relapse in ETV6-RUNX1 acute lymphoblastic leukemia.
van Delft FW, Horsley S, Colman S, Anderson K, Bateman C, Kempski H, Zuna J, Eckert C, Saha V, Kearney L, Ford A, Greaves M. van Delft FW, et al. Blood. 2011 Jun 9;117(23):6247-54. doi: 10.1182/blood-2010-10-314674. Epub 2011 Apr 11. Blood. 2011. PMID: 21482711 Free article.
CD2-positive B-cell precursor acute lymphoblastic leukemia with an early switch to the monocytic lineage.
Slamova L, Starkova J, Fronkova E, Zaliova M, Reznickova L, van Delft FW, Vodickova E, Volejnikova J, Zemanova Z, Polgarova K, Cario G, Figueroa M, Kalina T, Fiser K, Bourquin JP, Bornhauser B, Dworzak M, Zuna J, Trka J, Stary J, Hrusak O, Mejstrikova E. Slamova L, et al. Among authors: van delft fw. Leukemia. 2014 Mar;28(3):609-20. doi: 10.1038/leu.2013.354. Epub 2013 Nov 25. Leukemia. 2014. PMID: 24270736
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