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Inhibition of metalloprotease hyperactivity in cystic cholangiocytes halts the development of polycystic liver diseases.
Urribarri AD, Munoz-Garrido P, Perugorria MJ, Erice O, Merino-Azpitarte M, Arbelaiz A, Lozano E, Hijona E, Jiménez-Agüero R, Fernandez-Barrena MG, Jimeno JP, Marzioni M, Marin JJ, Masyuk TV, LaRusso NF, Prieto J, Bujanda L, Banales JM. Urribarri AD, et al. Among authors: larusso nf. Gut. 2014 Oct;63(10):1658-67. doi: 10.1136/gutjnl-2013-305281. Epub 2014 Jan 16. Gut. 2014. PMID: 24436140 Free PMC article.
Polycystic liver diseases: advanced insights into the molecular mechanisms.
Perugorria MJ, Masyuk TV, Marin JJ, Marzioni M, Bujanda L, LaRusso NF, Banales JM. Perugorria MJ, et al. Among authors: larusso nf. Nat Rev Gastroenterol Hepatol. 2014 Dec;11(12):750-61. doi: 10.1038/nrgastro.2014.155. Epub 2014 Sep 30. Nat Rev Gastroenterol Hepatol. 2014. PMID: 25266109 Free PMC article. Review.
Therapeutic Targets in Polycystic Liver Disease.
Masyuk TV, Masyuk AI, LaRusso NF. Masyuk TV, et al. Among authors: larusso nf. Curr Drug Targets. 2017;18(8):950-957. doi: 10.2174/1389450116666150427161743. Curr Drug Targets. 2017. PMID: 25915482 Free PMC article. Review.
Ursodeoxycholic acid inhibits hepatic cystogenesis in experimental models of polycystic liver disease.
Munoz-Garrido P, Marin JJ, Perugorria MJ, Urribarri AD, Erice O, Sáez E, Úriz M, Sarvide S, Portu A, Concepcion AR, Romero MR, Monte MJ, Santos-Laso Á, Hijona E, Jimenez-Agüero R, Marzioni M, Beuers U, Masyuk TV, LaRusso NF, Prieto J, Bujanda L, Drenth JP, Banales JM. Munoz-Garrido P, et al. Among authors: larusso nf. J Hepatol. 2015 Oct;63(4):952-61. doi: 10.1016/j.jhep.2015.05.023. Epub 2015 Jun 1. J Hepatol. 2015. PMID: 26044126 Free PMC article.
MicroRNA-506 promotes primary biliary cholangitis-like features in cholangiocytes and immune activation.
Erice O, Munoz-Garrido P, Vaquero J, Perugorria MJ, Fernandez-Barrena MG, Saez E, Santos-Laso A, Arbelaiz A, Jimenez-Agüero R, Fernandez-Irigoyen J, Santamaria E, Torrano V, Carracedo A, Ananthanarayanan M, Marzioni M, Prieto J, Beuers U, Oude Elferink RP, LaRusso NF, Bujanda L, Marin JJG, Banales JM. Erice O, et al. Among authors: larusso nf. Hepatology. 2018 Apr;67(4):1420-1440. doi: 10.1002/hep.29533. Epub 2018 Feb 21. Hepatology. 2018. PMID: 28922472 Free PMC article.
Proteostasis disturbances and endoplasmic reticulum stress contribute to polycystic liver disease: New therapeutic targets.
Santos-Laso A, Izquierdo-Sanchez L, Rodrigues PM, Huang BQ, Azkargorta M, Lapitz A, Munoz-Garrido P, Arbelaiz A, Caballero-Camino FJ, Fernández-Barrena MG, Jimenez-Agüero R, Argemi J, Aragon T, Elortza F, Marzioni M, Drenth JPH, LaRusso NF, Bujanda L, Perugorria MJ, Banales JM. Santos-Laso A, et al. Among authors: larusso nf. Liver Int. 2020 Jul;40(7):1670-1685. doi: 10.1111/liv.14485. Epub 2020 May 6. Liver Int. 2020. PMID: 32378324 Free PMC article.
Targeting UBC9-mediated protein hyper-SUMOylation in cystic cholangiocytes halts polycystic liver disease in experimental models.
Lee-Law PY, Olaizola P, Caballero-Camino FJ, Izquierdo-Sanchez L, Rodrigues PM, Santos-Laso A, Azkargorta M, Elortza F, Martinez-Chantar ML, Perugorria MJ, Aspichueta P, Marzioni M, LaRusso NF, Bujanda L, Drenth JPH, Banales JM. Lee-Law PY, et al. Among authors: larusso nf. J Hepatol. 2021 Feb;74(2):394-406. doi: 10.1016/j.jhep.2020.09.010. Epub 2020 Sep 17. J Hepatol. 2021. PMID: 32950589 Free PMC article.
Polycystic Liver Disease: Advances in Understanding and Treatment.
Masyuk TV, Masyuk AI, LaRusso NF. Masyuk TV, et al. Among authors: larusso nf. Annu Rev Pathol. 2022 Jan 24;17:251-269. doi: 10.1146/annurev-pathol-042320-121247. Epub 2021 Nov 1. Annu Rev Pathol. 2022. PMID: 34724412 Free PMC article. Review.
435 results