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Leveraging cross-species transcription factor binding site patterns: from diabetes risk loci to disease mechanisms.
Claussnitzer M, Dankel SN, Klocke B, Grallert H, Glunk V, Berulava T, Lee H, Oskolkov N, Fadista J, Ehlers K, Wahl S, Hoffmann C, Qian K, Rönn T, Riess H, Müller-Nurasyid M, Bretschneider N, Schroeder T, Skurk T, Horsthemke B; DIAGRAM+Consortium; Spieler D, Klingenspor M, Seifert M, Kern MJ, Mejhert N, Dahlman I, Hansson O, Hauck SM, Blüher M, Arner P, Groop L, Illig T, Suhre K, Hsu YH, Mellgren G, Hauner H, Laumen H. Claussnitzer M, et al. Among authors: horsthemke b. Cell. 2014 Jan 16;156(1-2):343-58. doi: 10.1016/j.cell.2013.10.058. Cell. 2014. PMID: 24439387 Free PMC article.
FTO levels affect RNA modification and the transcriptome.
Berulava T, Ziehe M, Klein-Hitpass L, Mladenov E, Thomale J, Rüther U, Horsthemke B. Berulava T, et al. Among authors: horsthemke b. Eur J Hum Genet. 2013 Mar;21(3):317-23. doi: 10.1038/ejhg.2012.168. Epub 2012 Aug 8. Eur J Hum Genet. 2013. PMID: 22872099 Free PMC article.
N6-adenosine methylation in MiRNAs.
Berulava T, Rahmann S, Rademacher K, Klein-Hitpass L, Horsthemke B. Berulava T, et al. Among authors: horsthemke b. PLoS One. 2015 Feb 27;10(2):e0118438. doi: 10.1371/journal.pone.0118438. eCollection 2015. PLoS One. 2015. PMID: 25723394 Free PMC article.
The human retinoblastoma gene is imprinted.
Kanber D, Berulava T, Ammerpohl O, Mitter D, Richter J, Siebert R, Horsthemke B, Lohmann D, Buiting K. Kanber D, et al. Among authors: horsthemke b. PLoS Genet. 2009 Dec;5(12):e1000790. doi: 10.1371/journal.pgen.1000790. Epub 2009 Dec 24. PLoS Genet. 2009. PMID: 20041224 Free PMC article.
The mechanisms of genomic imprinting.
Horsthemke B, Surani A, James T, Ohlsson R. Horsthemke B, et al. Results Probl Cell Differ. 1999;25:91-118. doi: 10.1007/978-3-540-69111-2_5. Results Probl Cell Differ. 1999. PMID: 10339743 Review. No abstract available.
A germ cell-specific ageing pattern in otherwise healthy men.
Laurentino S, Cremers JF, Horsthemke B, Tüttelmann F, Czeloth K, Zitzmann M, Pohl E, Rahmann S, Schröder C, Berres S, Redmann K, Krallmann C, Schlatt S, Kliesch S, Gromoll J. Laurentino S, et al. Among authors: horsthemke b. Aging Cell. 2020 Oct;19(10):e13242. doi: 10.1111/acel.13242. Epub 2020 Sep 20. Aging Cell. 2020. PMID: 32951333 Free PMC article.
Mechanisms of imprint dysregulation.
Horsthemke B. Horsthemke B. Am J Med Genet C Semin Med Genet. 2010 Aug 15;154C(3):321-8. doi: 10.1002/ajmg.c.30269. Am J Med Genet C Semin Med Genet. 2010. PMID: 20803654 Review.
292 results