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Leveraging cross-species transcription factor binding site patterns: from diabetes risk loci to disease mechanisms.
Claussnitzer M, Dankel SN, Klocke B, Grallert H, Glunk V, Berulava T, Lee H, Oskolkov N, Fadista J, Ehlers K, Wahl S, Hoffmann C, Qian K, Rönn T, Riess H, Müller-Nurasyid M, Bretschneider N, Schroeder T, Skurk T, Horsthemke B; DIAGRAM+Consortium; Spieler D, Klingenspor M, Seifert M, Kern MJ, Mejhert N, Dahlman I, Hansson O, Hauck SM, Blüher M, Arner P, Groop L, Illig T, Suhre K, Hsu YH, Mellgren G, Hauner H, Laumen H. Claussnitzer M, et al. Among authors: illig t. Cell. 2014 Jan 16;156(1-2):343-58. doi: 10.1016/j.cell.2013.10.058. Cell. 2014. PMID: 24439387 Free PMC article.
Meta-analysis and a large association study confirm a role for calpain-10 variation in type 2 diabetes susceptibility.
Weedon MN, Schwarz PE, Horikawa Y, Iwasaki N, Illig T, Holle R, Rathmann W, Selisko T, Schulze J, Owen KR, Evans J, Del Bosque-Plata L, Hitman G, Walker M, Levy JC, Sampson M, Bell GI, McCarthy MI, Hattersley AT, Frayling TM. Weedon MN, et al. Among authors: illig t. Am J Hum Genet. 2003 Nov;73(5):1208-12. doi: 10.1086/379285. Am J Hum Genet. 2003. PMID: 14574648 Free PMC article. No abstract available.
Melanocortin-4 receptor gene variant I103 is negatively associated with obesity.
Geller F, Reichwald K, Dempfle A, Illig T, Vollmert C, Herpertz S, Siffert W, Platzer M, Hess C, Gudermann T, Biebermann H, Wichmann HE, Schäfer H, Hinney A, Hebebrand J. Geller F, et al. Among authors: illig t. Am J Hum Genet. 2004 Mar;74(3):572-81. doi: 10.1086/382490. Epub 2004 Feb 17. Am J Hum Genet. 2004. PMID: 14973783 Free PMC article.
Significant association of the interleukin-6 gene polymorphisms C-174G and A-598G with type 2 diabetes.
Illig T, Bongardt F, Schöpfer A, Müller-Scholze S, Rathmann W, Koenig W, Thorand B, Vollmert C, Holle R, Kolb H, Herder C; Kooperative Gesundheitsforschung im Raum Augsburg/Cooperative Research in the Region of Augsburg. Illig T, et al. J Clin Endocrinol Metab. 2004 Oct;89(10):5053-8. doi: 10.1210/jc.2004-0355. J Clin Endocrinol Metab. 2004. PMID: 15472205
Linkage disequilibrium patterns and tagSNP transferability among European populations.
Mueller JC, Lõhmussaar E, Mägi R, Remm M, Bettecken T, Lichtner P, Biskup S, Illig T, Pfeufer A, Luedemann J, Schreiber S, Pramstaller P, Pichler I, Romeo G, Gaddi A, Testa A, Wichmann HE, Metspalu A, Meitinger T. Mueller JC, et al. Among authors: illig t. Am J Hum Genet. 2005 Mar;76(3):387-98. doi: 10.1086/427925. Epub 2005 Jan 6. Am J Hum Genet. 2005. PMID: 15637659 Free PMC article.
Common variants in myocardial ion channel genes modify the QT interval in the general population: results from the KORA study.
Pfeufer A, Jalilzadeh S, Perz S, Mueller JC, Hinterseer M, Illig T, Akyol M, Huth C, Schöpfer-Wendels A, Kuch B, Steinbeck G, Holle R, Näbauer M, Wichmann HE, Meitinger T, Kääb S. Pfeufer A, et al. Among authors: illig t. Circ Res. 2005 Apr 1;96(6):693-701. doi: 10.1161/01.RES.0000161077.53751.e6. Epub 2005 Mar 3. Circ Res. 2005. PMID: 15746444
697 results