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Regulation of allergy by Fc receptors.
Bruhns P, Frémont S, Daëron M. Bruhns P, et al. Curr Opin Immunol. 2005 Dec;17(6):662-9. doi: 10.1016/j.coi.2005.09.012. Epub 2005 Oct 7. Curr Opin Immunol. 2005. PMID: 16214316 Free article. Review.
Autonomous phagosomal degradation and antigen presentation in dendritic cells.
Hoffmann E, Kotsias F, Visentin G, Bruhns P, Savina A, Amigorena S. Hoffmann E, et al. Among authors: bruhns p. Proc Natl Acad Sci U S A. 2012 Sep 4;109(36):14556-61. doi: 10.1073/pnas.1203912109. Epub 2012 Aug 20. Proc Natl Acad Sci U S A. 2012. PMID: 22908282 Free PMC article.
Mouse and human FcR effector functions.
Bruhns P, Jönsson F. Bruhns P, et al. Immunol Rev. 2015 Nov;268(1):25-51. doi: 10.1111/imr.12350. Immunol Rev. 2015. PMID: 26497511 Review.
IgG Fc domains that bind C1q but not effector Fcγ receptors delineate the importance of complement-mediated effector functions.
Lee CH, Romain G, Yan W, Watanabe M, Charab W, Todorova B, Lee J, Triplett K, Donkor M, Lungu OI, Lux A, Marshall N, Lindorfer MA, Goff OR, Balbino B, Kang TH, Tanno H, Delidakis G, Alford C, Taylor RP, Nimmerjahn F, Varadarajan N, Bruhns P, Zhang YJ, Georgiou G. Lee CH, et al. Among authors: bruhns p. Nat Immunol. 2017 Aug;18(8):889-898. doi: 10.1038/ni.3770. Epub 2017 Jun 12. Nat Immunol. 2017. PMID: 28604720 Free PMC article.
An Engineered Human Fc variant With Exquisite Selectivity for FcγRIIIaV158 Reveals That Ligation of FcγRIIIa Mediates Potent Antibody Dependent Cellular Phagocytosis With GM-CSF-Differentiated Macrophages.
Kang TH, Lee CH, Delidakis G, Jung J, Richard-Le Goff O, Lee J, Kim JE, Charab W, Bruhns P, Georgiou G. Kang TH, et al. Among authors: bruhns p. Front Immunol. 2019 Mar 27;10:562. doi: 10.3389/fimmu.2019.00562. eCollection 2019. Front Immunol. 2019. PMID: 30984171 Free PMC article.
The anti-IgE mAb omalizumab induces adverse reactions by engaging Fcγ receptors.
Balbino B, Herviou P, Godon O, Stackowicz J, Goff OR, Iannascoli B, Sterlin D, Brûlé S, Millot GA, Harris FM, Voronina VA, Nadeau KC, Macdonald LE, Murphy AJ, Bruhns P, Reber LL. Balbino B, et al. Among authors: bruhns p. J Clin Invest. 2020 Mar 2;130(3):1330-1335. doi: 10.1172/JCI129697. J Clin Invest. 2020. PMID: 31770111 Free PMC article.
Autoantibodies neutralizing type I IFNs are present in ~4% of uninfected individuals over 70 years old and account for ~20% of COVID-19 deaths.
Bastard P, Gervais A, Le Voyer T, Rosain J, Philippot Q, Manry J, Michailidis E, Hoffmann HH, Eto S, Garcia-Prat M, Bizien L, Parra-Martínez A, Yang R, Haljasmägi L, Migaud M, Särekannu K, Maslovskaja J, de Prost N, Tandjaoui-Lambiotte Y, Luyt CE, Amador-Borrero B, Gaudet A, Poissy J, Morel P, Richard P, Cognasse F, Troya J, Trouillet-Assant S, Belot A, Saker K, Garçon P, Rivière JG, Lagier JC, Gentile S, Rosen LB, Shaw E, Morio T, Tanaka J, Dalmau D, Tharaux PL, Sene D, Stepanian A, Megarbane B, Triantafyllia V, Fekkar A, Heath JR, Franco JL, Anaya JM, Solé-Violán J, Imberti L, Biondi A, Bonfanti P, Castagnoli R, Delmonte OM, Zhang Y, Snow AL, Holland SM, Biggs C, Moncada-Vélez M, Arias AA, Lorenzo L, Boucherit S, Coulibaly B, Anglicheau D, Planas AM, Haerynck F, Duvlis S, Nussbaum RL, Ozcelik T, Keles S, Bousfiha AA, El Bakkouri J, Ramirez-Santana C, Paul S, Pan-Hammarström Q, Hammarström L, Dupont A, Kurolap A, Metz CN, Aiuti A, Casari G, Lampasona V, Ciceri F, Barreiros LA, Dominguez-Garrido E, Vidigal M, Zatz M, van de Beek D, Sahanic S, Tancevski I, Stepanovskyy Y, Boyarchuk O, Nukui Y, Tsumura M, Vidaur L, Tangye SG, Burrel S, Duffy D, Quintana-Murci L, Klocperk A, Kann NY,… See abstract for full author list ➔ Bastard P, et al. Sci Immunol. 2021 Aug 19;6(62):eabl4340. doi: 10.1126/sciimmunol.abl4340. Sci Immunol. 2021. PMID: 34413139 Free PMC article.
126 results