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Cross-talk between EphA2 and BRaf/CRaf is a key determinant of response to Dasatinib.
Huang J, Hu W, Bottsford-Miller J, Liu T, Han HD, Zand B, Pradeep S, Roh JW, Thanapprapasr D, Dalton HJ, Pecot CV, Rupaimoole R, Lu C, Fellman B, Urbauer D, Kang Y, Jennings NB, Huang L, Deavers MT, Broaddus R, Coleman RL, Sood AK. Huang J, et al. Among authors: huang l. Clin Cancer Res. 2014 Apr 1;20(7):1846-55. doi: 10.1158/1078-0432.CCR-13-2141. Epub 2014 Jan 31. Clin Cancer Res. 2014. PMID: 24486585 Free PMC article.
Biological roles of the Delta family Notch ligand Dll4 in tumor and endothelial cells in ovarian cancer.
Hu W, Lu C, Dong HH, Huang J, Shen DY, Stone RL, Nick AM, Shahzad MM, Mora E, Jennings NB, Lee SJ, Roh JW, Matsuo K, Nishimura M, Goodman BW, Jaffe RB, Langley RR, Deavers MT, Lopez-Berestein G, Coleman RL, Sood AK. Hu W, et al. Among authors: huang j. Cancer Res. 2011 Sep 15;71(18):6030-9. doi: 10.1158/0008-5472.CAN-10-2719. Epub 2011 Jul 27. Cancer Res. 2011. PMID: 21795478 Free PMC article.
Metronomic activity of CD44-targeted hyaluronic acid-paclitaxel in ovarian carcinoma.
Lee SJ, Ghosh SC, Han HD, Stone RL, Bottsford-Miller J, Shen DY, Auzenne EJ, Lopez-Araujo A, Lu C, Nishimura M, Pecot CV, Zand B, Thanapprapasr D, Jennings NB, Kang Y, Huang J, Hu W, Klostergaard J, Sood AK. Lee SJ, et al. Among authors: huang j. Clin Cancer Res. 2012 Aug 1;18(15):4114-21. doi: 10.1158/1078-0432.CCR-11-3250. Epub 2012 Jun 12. Clin Cancer Res. 2012. PMID: 22693353 Free PMC article.
Role of focal adhesion kinase in regulating YB-1-mediated paclitaxel resistance in ovarian cancer.
Kang Y, Hu W, Ivan C, Dalton HJ, Miyake T, Pecot CV, Zand B, Liu T, Huang J, Jennings NB, Rupaimoole R, Taylor M, Pradeep S, Wu SY, Lu C, Wen Y, Huang J, Liu J, Sood AK. Kang Y, et al. Among authors: huang j. J Natl Cancer Inst. 2013 Oct 2;105(19):1485-95. doi: 10.1093/jnci/djt210. Epub 2013 Sep 23. J Natl Cancer Inst. 2013. PMID: 24062525 Free PMC article.
Targeting SRC and tubulin in mucinous ovarian carcinoma.
Liu T, Hu W, Dalton HJ, Choi HJ, Huang J, Kang Y, Pradeep S, Miyake T, Song JH, Wen Y, Lu C, Pecot CV, Bottsford-Miller J, Zand B, Jennings NB, Ivan C, Gallick GE, Baggerly KA, Hangauer DG, Coleman RL, Frumovitz M, Sood AK. Liu T, et al. Among authors: huang j. Clin Cancer Res. 2013 Dec 1;19(23):6532-43. doi: 10.1158/1078-0432.CCR-13-1305. Epub 2013 Oct 7. Clin Cancer Res. 2013. PMID: 24100628 Free PMC article.
Biologic effects of platelet-derived growth factor receptor α blockade in uterine cancer.
Roh JW, Huang J, Hu W, Yang X, Jennings NB, Sehgal V, Sohn BH, Han HD, Lee SJ, Thanapprapasr D, Bottsford-Miller J, Zand B, Dalton HJ, Previs RA, Davis AN, Matsuo K, Lee JS, Ram P, Coleman RL, Sood AK. Roh JW, et al. Among authors: huang j. Clin Cancer Res. 2014 May 15;20(10):2740-50. doi: 10.1158/1078-0432.CCR-13-2507. Epub 2014 Mar 14. Clin Cancer Res. 2014. PMID: 24634380 Free PMC article.
Notch3 pathway alterations in ovarian cancer.
Hu W, Liu T, Ivan C, Sun Y, Huang J, Mangala LS, Miyake T, Dalton HJ, Pradeep S, Rupaimoole R, Previs RA, Han HD, Bottsford-Miller J, Zand B, Kang Y, Pecot CV, Nick AM, Wu SY, Lee JS, Sehgal V, Ram P, Liu J, Tucker SL, Lopez-Berestein G, Baggerly KA, Coleman RL, Sood AK. Hu W, et al. Among authors: huang j. Cancer Res. 2014 Jun 15;74(12):3282-93. doi: 10.1158/0008-5472.CAN-13-2066. Epub 2014 Apr 17. Cancer Res. 2014. PMID: 24743243 Free PMC article.
Dll4 Inhibition plus Aflibercept Markedly Reduces Ovarian Tumor Growth.
Huang J, Hu W, Hu L, Previs RA, Dalton HJ, Yang XY, Sun Y, McGuire M, Rupaimoole R, Nagaraja AS, Kang Y, Liu T, Nick AM, Jennings NB, Coleman RL, Jaffe RB, Sood AK. Huang J, et al. Mol Cancer Ther. 2016 Jun;15(6):1344-52. doi: 10.1158/1535-7163.MCT-15-0144. Epub 2016 Mar 23. Mol Cancer Ther. 2016. PMID: 27009216 Free PMC article.
Inhibiting Nuclear Phospho-Progesterone Receptor Enhances Antitumor Activity of Onapristone in Uterine Cancer.
Huang Y, Hu W, Huang J, Shen F, Sun Y, Ivan C, Pradeep S, Dood R, Haemmerle M, Jiang D, Mangala LS, Noh K, Hansen JM, Dalton HJ, Previs RA, Nagaraja AS, McGuire M, Jennings NB, Broaddus R, Coleman RL, Sood AK. Huang Y, et al. Among authors: huang j. Mol Cancer Ther. 2018 Feb;17(2):464-473. doi: 10.1158/1535-7163.MCT-17-0006. Epub 2017 Dec 13. Mol Cancer Ther. 2018. PMID: 29237804 Free PMC article.
MEK inhibition overcomes resistance to EphA2-targeted therapy in uterine cancer.
Wu Y, Huang J, Ivan C, Sun Y, Ma S, Mangala LS, Fellman BM, Urbauer DL, Jennings NB, Ram P, Coleman RL, Hu W, Sood AK. Wu Y, et al. Among authors: huang j. Gynecol Oncol. 2021 Oct;163(1):181-190. doi: 10.1016/j.ygyno.2021.08.003. Epub 2021 Aug 11. Gynecol Oncol. 2021. PMID: 34391578 Free PMC article.
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