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DNA methylation profile associated with rapid decline in kidney function: findings from the CRIC study.
Wing MR, Devaney JM, Joffe MM, Xie D, Feldman HI, Dominic EA, Guzman NJ, Ramezani A, Susztak K, Herman JG, Cope L, Harmon B, Kwabi-Addo B, Gordish-Dressman H, Go AS, He J, Lash JP, Kusek JW, Raj DS; Chronic Renal Insufficiency Cohort (CRIC) Study. Wing MR, et al. Among authors: devaney jm. Nephrol Dial Transplant. 2014 Apr;29(4):864-72. doi: 10.1093/ndt/gft537. Epub 2014 Feb 9. Nephrol Dial Transplant. 2014. PMID: 24516231 Free PMC article.
Genetic associations at 53 loci highlight cell types and biological pathways relevant for kidney function.
Pattaro C, Teumer A, Gorski M, Chu AY, Li M, Mijatovic V, Garnaas M, Tin A, Sorice R, Li Y, Taliun D, Olden M, Foster M, Yang Q, Chen MH, Pers TH, Johnson AD, Ko YA, Fuchsberger C, Tayo B, Nalls M, Feitosa MF, Isaacs A, Dehghan A, d'Adamo P, Adeyemo A, Dieffenbach AK, Zonderman AB, Nolte IM, van der Most PJ, Wright AF, Shuldiner AR, Morrison AC, Hofman A, Smith AV, Dreisbach AW, Franke A, Uitterlinden AG, Metspalu A, Tonjes A, Lupo A, Robino A, Johansson Å, Demirkan A, Kollerits B, Freedman BI, Ponte B, Oostra BA, Paulweber B, Krämer BK, Mitchell BD, Buckley BM, Peralta CA, Hayward C, Helmer C, Rotimi CN, Shaffer CM, Müller C, Sala C, van Duijn CM, Saint-Pierre A, Ackermann D, Shriner D, Ruggiero D, Toniolo D, Lu Y, Cusi D, Czamara D, Ellinghaus D, Siscovick DS, Ruderfer D, Gieger C, Grallert H, Rochtchina E, Atkinson EJ, Holliday EG, Boerwinkle E, Salvi E, Bottinger EP, Murgia F, Rivadeneira F, Ernst F, Kronenberg F, Hu FB, Navis GJ, Curhan GC, Ehret GB, Homuth G, Coassin S, Thun GA, Pistis G, Gambaro G, Malerba G, Montgomery GW, Eiriksdottir G, Jacobs G, Li G, Wichmann HE, Campbell H, Schmidt H, Wallaschofski H, Völzke H, Brenner H, Kroemer HK, Kramer H, Lin H, Leach IM, Ford I,… See abstract for full author list ➔ Pattaro C, et al. Nat Commun. 2016 Jan 21;7:10023. doi: 10.1038/ncomms10023. Nat Commun. 2016. PMID: 26831199 Free PMC article.
CCL2 and CCR2 variants are associated with skeletal muscle strength and change in strength with resistance training.
Harmon BT, Orkunoglu-Suer EF, Adham K, Larkin JS, Gordish-Dressman H, Clarkson PM, Thompson PD, Angelopoulos TJ, Gordon PM, Moyna NM, Pescatello LS, Visich PS, Zoeller RF, Hubal MJ, Tosi LL, Hoffman EP, Devaney JM. Harmon BT, et al. Among authors: devaney jm. J Appl Physiol (1985). 2010 Dec;109(6):1779-85. doi: 10.1152/japplphysiol.00633.2010. Epub 2010 Oct 14. J Appl Physiol (1985). 2010. PMID: 20947712 Free PMC article.
INSIG2 gene polymorphism is associated with increased subcutaneous fat in women and poor response to resistance training in men.
Orkunoglu-Suer FE, Gordish-Dressman H, Clarkson PM, Thompson PD, Angelopoulos TJ, Gordon PM, Moyna NM, Pescatello LS, Visich PS, Zoeller RF, Harmon B, Seip RL, Hoffman EP, Devaney JM. Orkunoglu-Suer FE, et al. Among authors: devaney jm. BMC Med Genet. 2008 Dec 23;9:117. doi: 10.1186/1471-2350-9-117. BMC Med Genet. 2008. PMID: 19105843 Free PMC article.
MC4R variant is associated with BMI but not response to resistance training in young females.
Orkunoglu-Suer FE, Harmon BT, Gordish-Dressman H, Clarkson PM, Thompson PD, Angelopoulos TJ, Gordon PM, Hubal MJ, Moyna NM, Pescatello LS, Visich PS, Zoeller RF, Hoffman EP, Devaney JM. Orkunoglu-Suer FE, et al. Among authors: devaney jm. Obesity (Silver Spring). 2011 Mar;19(3):662-6. doi: 10.1038/oby.2010.180. Epub 2010 Aug 19. Obesity (Silver Spring). 2011. PMID: 20725061 Free PMC article.
The 1p13.3 LDL (C)-associated locus shows large effect sizes in young populations.
Devaney JM, Thompson PD, Visich PS, Saltarelli WA, Gordon PM, Orkunoglu-Suer EF, Gordish-Dressman H, Harmon BT, Bradbury MK, Panchapakesan K, Khianey R, Hubal MJ, Clarkson PM, Pescatello LS, Zoeller RF, Moyna NM, Angelopoulos TJ, Kraus WE, Hoffman EP. Devaney JM, et al. Pediatr Res. 2011 Jun;69(6):538-43. doi: 10.1203/PDR.0b013e3182139227. Pediatr Res. 2011. PMID: 21297524 Free PMC article.
134 results