Kovalevsky AY - Search Results

1

Novel complex MAD phasing and RNase H structural insights using selenium oligonucleotides.

Abdur R, Gerlits OO, Gan J, Jiang J, Salon J, Kovalevsky AY, Chumanevich AA, Weber IT, Huang Z. Abdur R, et al. Among authors: kovalevsky ay. Acta Crystallogr D Biol Crystallogr. 2014 Feb;70(Pt 2):354-61. doi: 10.1107/S1399004713027922. Epub 2014 Jan 29. Acta Crystallogr D Biol Crystallogr. 2014. PMID: 24531469 Free PMC article.

2

A very large Rh-Rh bond shortening on excitation of the [Rh2(1,8-diisocyano-p-menthane)4]2+ ion by time-resolved synchrotron X-ray diffraction.

Coppens P, Gerlits O, Vorontsov II, Kovalevsky AY, Chen YS, Graber T, Gembicky M, Novozhilova IV. Coppens P, et al. Among authors: kovalevsky ay. Chem Commun (Camb). 2004 Oct 7;(19):2144-5. doi: 10.1039/b409463h. Epub 2004 Aug 19. Chem Commun (Camb). 2004. PMID: 15467843

3

Solid-state spectroscopic properties and the geometry of binuclear rhodium(I) diisocyanoalkane complexes.

Gerlits O, Kovalevsky AY, Coppens P. Gerlits O, et al. Among authors: kovalevsky ay. Dalton Trans. 2004 Dec 7;(23):3955-62. doi: 10.1039/b412942c. Epub 2004 Oct 27. Dalton Trans. 2004. PMID: 15558120

4

Effectiveness of nonpeptide clinical inhibitor TMC-114 on HIV-1 protease with highly drug resistant mutations D30N, I50V, and L90M.

Kovalevsky AY, Tie Y, Liu F, Boross PI, Wang YF, Leshchenko S, Ghosh AK, Harrison RW, Weber IT. Kovalevsky AY, et al. J Med Chem. 2006 Feb 23;49(4):1379-87. doi: 10.1021/jm050943c. J Med Chem. 2006. PMID: 16480273 Free PMC article.

5

Mechanism of drug resistance revealed by the crystal structure of the unliganded HIV-1 protease with F53L mutation.

Liu F, Kovalevsky AY, Louis JM, Boross PI, Wang YF, Harrison RW, Weber IT. Liu F, et al. Among authors: kovalevsky ay. J Mol Biol. 2006 May 19;358(5):1191-9. doi: 10.1016/j.jmb.2006.02.076. Epub 2006 Mar 20. J Mol Biol. 2006. PMID: 16569415

6

Structure-based design of novel HIV-1 protease inhibitors to combat drug resistance.

Ghosh AK, Sridhar PR, Leshchenko S, Hussain AK, Li J, Kovalevsky AY, Walters DE, Wedekind JE, Grum-Tokars V, Das D, Koh Y, Maeda K, Gatanaga H, Weber IT, Mitsuya H. Ghosh AK, et al. Among authors: kovalevsky ay. J Med Chem. 2006 Aug 24;49(17):5252-61. doi: 10.1021/jm060561m. J Med Chem. 2006. PMID: 16913714

7

Ultra-high resolution crystal structure of HIV-1 protease mutant reveals two binding sites for clinical inhibitor TMC114.

Kovalevsky AY, Liu F, Leshchenko S, Ghosh AK, Louis JM, Harrison RW, Weber IT. Kovalevsky AY, et al. J Mol Biol. 2006 Oct 13;363(1):161-73. doi: 10.1016/j.jmb.2006.08.007. Epub 2006 Aug 4. J Mol Biol. 2006. PMID: 16962136 Free PMC article.

8

Atomic resolution crystal structures of HIV-1 protease and mutants V82A and I84V with saquinavir.

Tie Y, Kovalevsky AY, Boross P, Wang YF, Ghosh AK, Tozser J, Harrison RW, Weber IT. Tie Y, et al. Among authors: kovalevsky ay. Proteins. 2007 Apr 1;67(1):232-42. doi: 10.1002/prot.21304. Proteins. 2007. PMID: 17243183

9

Caught in the Act: the 1.5 A resolution crystal structures of the HIV-1 protease and the I54V mutant reveal a tetrahedral reaction intermediate.

Kovalevsky AY, Chumanevich AA, Liu F, Louis JM, Weber IT. Kovalevsky AY, et al. Biochemistry. 2007 Dec 25;46(51):14854-64. doi: 10.1021/bi700822g. Epub 2007 Dec 4. Biochemistry. 2007. PMID: 18052235 Free PMC article.

10

Effect of flap mutations on structure of HIV-1 protease and inhibition by saquinavir and darunavir.

Liu F, Kovalevsky AY, Tie Y, Ghosh AK, Harrison RW, Weber IT. Liu F, et al. Among authors: kovalevsky ay. J Mol Biol. 2008 Aug 1;381(1):102-15. doi: 10.1016/j.jmb.2008.05.062. Epub 2008 Jul 1. J Mol Biol. 2008. PMID: 18597780 Free PMC article.

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