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A selective USP1-UAF1 inhibitor links deubiquitination to DNA damage responses.
Liang Q, Dexheimer TS, Zhang P, Rosenthal AS, Villamil MA, You C, Zhang Q, Chen J, Ott CA, Sun H, Luci DK, Yuan B, Simeonov A, Jadhav A, Xiao H, Wang Y, Maloney DJ, Zhuang Z. Liang Q, et al. Among authors: ott ca. Nat Chem Biol. 2014 Apr;10(4):298-304. doi: 10.1038/nchembio.1455. Epub 2014 Feb 16. Nat Chem Biol. 2014. PMID: 24531842 Free PMC article.
SOX10 Loss Sensitizes Melanoma Cells to Cytokine-Mediated Inflammatory Cell Death.
Rosenbaum SR, Caksa S, Stefanski CD, Trachtenberg IV, Wilson HP, Wilski NA, Ott CA, Purwin TJ, Haj JI, Pomante D, Kotas D, Chervoneva I, Capparelli C, Aplin AE. Rosenbaum SR, et al. Among authors: ott ca. Mol Cancer Res. 2024 Feb 1;22(2):209-220. doi: 10.1158/1541-7786.MCR-23-0290. Mol Cancer Res. 2024. PMID: 37847239
Targeting TEAD-ious resistance.
Ott CA, Aplin AE. Ott CA, et al. Trends Cancer. 2023 Oct;9(10):780-781. doi: 10.1016/j.trecan.2023.07.016. Epub 2023 Aug 3. Trends Cancer. 2023. PMID: 37543514
37 results