Zhang L - Search Results

1

High-throughput high-content imaging assays for identification and characterization of selective AXL pathway inhibitors.

Tang H, Yang J, Shen DR, Calambur D, Witmer M, Wu S, Carpenter B, Zhang Y, Gao M, Constantine K, Zhang L, Cvijic ME. Tang H, et al. Among authors: zhang l, zhang y. Assay Drug Dev Technol. 2014 Jan-Feb;12(1):80-6. doi: 10.1089/adt.2013.540. Assay Drug Dev Technol. 2014. PMID: 24547742

2

Development of novel, 384-well high-throughput assay panels for human drug transporters: drug interaction and safety assessment in support of discovery research.

Tang H, Shen DR, Han YH, Kong Y, Balimane P, Marino A, Gao M, Wu S, Xie D, Soars MG, O'Connell JC, Rodrigues AD, Zhang L, Cvijic ME. Tang H, et al. Among authors: zhang l. J Biomol Screen. 2013 Oct;18(9):1072-83. doi: 10.1177/1087057113494807. J Biomol Screen. 2013. PMID: 24062352

3

GPCR assay automation for leveraging lead optimization.

Cvijic ME, Chen J, Kubala S, Nolfo J, Kolodin G, Zhang L. Cvijic ME, et al. Among authors: zhang l. J Lab Autom. 2012 Aug;17(4):266-74. doi: 10.1177/2211068212442502. Epub 2012 Apr 13. J Lab Autom. 2012. PMID: 22505604

4

Integrating High-Content Analysis into a Multiplexed Screening Approach to Identify and Characterize GPCR Agonists.

Zhu Y, Watson J, Chen M, Shen DR, Yarde M, Agler M, Burford N, Alt A, Jayachandra S, Cvijic ME, Zhang L, Dyckman A, Xie J, O'Connell J, Banks M, Weston A. Zhu Y, et al. Among authors: zhang l. J Biomol Screen. 2014 Aug;19(7):1079-89. doi: 10.1177/1087057114533146. Epub 2014 Apr 30. J Biomol Screen. 2014. PMID: 24789006

5

GPCR profiling: from hits to leads and from genotype to phenotype.

Cvijic ME, Sum CS, Alt A, Zhang L. Cvijic ME, et al. Among authors: zhang l. Drug Discov Today Technol. 2015 Nov;18:30-7. doi: 10.1016/j.ddtec.2015.10.005. Epub 2015 Nov 6. Drug Discov Today Technol. 2015. PMID: 26723890 Review.

6

384-Well Multiplexed Luminex Cytokine Assays for Lead Optimization.

Tang H, Panemangalore R, Yarde M, Zhang L, Cvijic ME. Tang H, et al. Among authors: zhang l. J Biomol Screen. 2016 Jul;21(6):548-55. doi: 10.1177/1087057116644164. Epub 2016 Apr 19. J Biomol Screen. 2016. PMID: 27095819

7

Leveraging the IncuCyte Technology for Higher-Throughput and Automated Chemotaxis Assays for Target Validation and Compound Characterization.

Chen J, Ribeiro B, Li H, Myer L, Chase P, Surti N, Lippy J, Zhang L, Cvijic ME. Chen J, et al. Among authors: zhang l. SLAS Discov. 2018 Feb;23(2):122-131. doi: 10.1177/2472555217733437. Epub 2017 Sep 28. SLAS Discov. 2018. PMID: 28957636 Free article.

8

Case study: technology initiative led to advanced lead optimization screening processes at Bristol-Myers Squibb, 2004-2009.

Zhang L, Cvijic ME, Lippy J, Myslik J, Brenner SL, Binnie A, Houston JG. Zhang L, et al. Drug Discov Today. 2012 Jul;17(13-14):733-40. doi: 10.1016/j.drudis.2012.02.012. Epub 2012 Mar 7. Drug Discov Today. 2012. PMID: 22425710 Review.

9

Development of a RapidFire mass spectrometry assay and a fluorescence assay for the discovery of kynurenine aminotransferase II inhibitors to treat central nervous system disorders.

Lu H, Kopcho L, Ghosh K, Witmer M, Parker M, Gupta S, Paul M, Krishnamurthy P, Laksmaiah B, Xie D, Tredup J, Zhang L, Abell LM. Lu H, et al. Among authors: zhang l. Anal Biochem. 2016 May 15;501:56-65. doi: 10.1016/j.ab.2016.02.003. Epub 2016 Feb 11. Anal Biochem. 2016. PMID: 26874021

10

Evidence for Classical Cholinergic Toxicity Associated with Selective Activation of M1 Muscarinic Receptors.

Alt A, Pendri A, Bertekap RL Jr, Li G, Benitex Y, Nophsker M, Rockwell KL, Burford NT, Sum CS, Chen J, Herbst JJ, Ferrante M, Hendricson A, Cvijic ME, Westphal RS, O'Connell J, Banks M, Zhang L, Gentles RG, Jenkins S, Loy J, Macor JE. Alt A, et al. Among authors: zhang l. J Pharmacol Exp Ther. 2016 Feb;356(2):293-304. doi: 10.1124/jpet.115.226910. Epub 2015 Nov 18. J Pharmacol Exp Ther. 2016. PMID: 26582730

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