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OGFOD1 catalyzes prolyl hydroxylation of RPS23 and is involved in translation control and stress granule formation.
Singleton RS, Liu-Yi P, Formenti F, Ge W, Sekirnik R, Fischer R, Adam J, Pollard PJ, Wolf A, Thalhammer A, Loenarz C, Flashman E, Yamamoto A, Coleman ML, Kessler BM, Wappner P, Schofield CJ, Ratcliffe PJ, Cockman ME. Singleton RS, et al. Among authors: flashman e. Proc Natl Acad Sci U S A. 2014 Mar 18;111(11):4031-6. doi: 10.1073/pnas.1314482111. Epub 2014 Feb 18. Proc Natl Acad Sci U S A. 2014. PMID: 24550447 Free PMC article.
OS-9: another piece in the HIF complex story.
Flashman E, McDonough MA, Schofield CJ. Flashman E, et al. Mol Cell. 2005 Feb 18;17(4):472-3. doi: 10.1016/j.molcel.2005.02.001. Mol Cell. 2005. PMID: 15721249 Free article. Review.
Cellular oxygen sensing: Crystal structure of hypoxia-inducible factor prolyl hydroxylase (PHD2).
McDonough MA, Li V, Flashman E, Chowdhury R, Mohr C, Liénard BM, Zondlo J, Oldham NJ, Clifton IJ, Lewis J, McNeill LA, Kurzeja RJ, Hewitson KS, Yang E, Jordan S, Syed RS, Schofield CJ. McDonough MA, et al. Among authors: flashman e. Proc Natl Acad Sci U S A. 2006 Jun 27;103(26):9814-9. doi: 10.1073/pnas.0601283103. Epub 2006 Jun 16. Proc Natl Acad Sci U S A. 2006. PMID: 16782814 Free PMC article.
The most versatile of all reactive intermediates?
Flashman E, Schofield CJ. Flashman E, et al. Nat Chem Biol. 2007 Feb;3(2):86-7. doi: 10.1038/nchembio0207-86. Nat Chem Biol. 2007. PMID: 17235343 No abstract available.
Dynamic states of the DNA repair enzyme AlkB regulate product release.
Bleijlevens B, Shivarattan T, Flashman E, Yang Y, Simpson PJ, Koivisto P, Sedgwick B, Schofield CJ, Matthews SJ. Bleijlevens B, et al. Among authors: flashman e. EMBO Rep. 2008 Sep;9(9):872-7. doi: 10.1038/embor.2008.120. Epub 2008 Jul 11. EMBO Rep. 2008. PMID: 18617893 Free PMC article.
Evidence for a stereoelectronic effect in human oxygen sensing.
Loenarz C, Mecinović J, Chowdhury R, McNeill LA, Flashman E, Schofield CJ. Loenarz C, et al. Among authors: flashman e. Angew Chem Int Ed Engl. 2009;48(10):1784-7. doi: 10.1002/anie.200805427. Angew Chem Int Ed Engl. 2009. PMID: 19180614
58 results