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Page 1
A type I interferon transcriptional signature precedes autoimmunity in children genetically at risk for type 1 diabetes.
Ferreira RC, Guo H, Coulson RM, Smyth DJ, Pekalski ML, Burren OS, Cutler AJ, Doecke JD, Flint S, McKinney EF, Lyons PA, Smith KG, Achenbach P, Beyerlein A, Dunger DB, Clayton DG, Wicker LS, Todd JA, Bonifacio E, Wallace C, Ziegler AG. Ferreira RC, et al. Among authors: dunger db. Diabetes. 2014 Jul;63(7):2538-50. doi: 10.2337/db13-1777. Epub 2014 Feb 21. Diabetes. 2014. PMID: 24561305 Free PMC article.
Replication of an association between the lymphoid tyrosine phosphatase locus (LYP/PTPN22) with type 1 diabetes, and evidence for its role as a general autoimmunity locus.
Smyth D, Cooper JD, Collins JE, Heward JM, Franklyn JA, Howson JM, Vella A, Nutland S, Rance HE, Maier L, Barratt BJ, Guja C, Ionescu-Tîrgoviste C, Savage DA, Dunger DB, Widmer B, Strachan DP, Ring SM, Walker N, Clayton DG, Twells RC, Gough SC, Todd JA. Smyth D, et al. Among authors: dunger db. Diabetes. 2004 Nov;53(11):3020-3. doi: 10.2337/diabetes.53.11.3020. Diabetes. 2004. PMID: 15504986
Association of the vitamin D metabolism gene CYP27B1 with type 1 diabetes.
Bailey R, Cooper JD, Zeitels L, Smyth DJ, Yang JH, Walker NM, Hyppönen E, Dunger DB, Ramos-Lopez E, Badenhoop K, Nejentsev S, Todd JA. Bailey R, et al. Among authors: dunger db. Diabetes. 2007 Oct;56(10):2616-21. doi: 10.2337/db07-0652. Epub 2007 Jul 2. Diabetes. 2007. PMID: 17606874 Free PMC article.
IL-21 production by CD4+ effector T cells and frequency of circulating follicular helper T cells are increased in type 1 diabetes patients.
Ferreira RC, Simons HZ, Thompson WS, Cutler AJ, Dopico XC, Smyth DJ, Mashar M, Schuilenburg H, Walker NM, Dunger DB, Wallace C, Todd JA, Wicker LS, Pekalski ML. Ferreira RC, et al. Among authors: dunger db. Diabetologia. 2015 Apr;58(4):781-90. doi: 10.1007/s00125-015-3509-8. Epub 2015 Feb 6. Diabetologia. 2015. PMID: 25652388 Free PMC article.
Circulating C-Peptide Levels in Living Children and Young People and Pancreatic β-Cell Loss in Pancreas Donors Across Type 1 Diabetes Disease Duration.
Carr ALJ, Inshaw JRJ, Flaxman CS, Leete P, Wyatt RC, Russell LA, Palmer M, Prasolov D, Worthington T, Hull B, Wicker LS, Dunger DB, Oram RA, Morgan NG, Todd JA, Richardson SJ, Besser REJ. Carr ALJ, et al. Among authors: dunger db. Diabetes. 2022 Jul 1;71(7):1591-1596. doi: 10.2337/db22-0097. Diabetes. 2022. PMID: 35499624 Free PMC article.
Robust associations of four new chromosome regions from genome-wide analyses of type 1 diabetes.
Todd JA, Walker NM, Cooper JD, Smyth DJ, Downes K, Plagnol V, Bailey R, Nejentsev S, Field SF, Payne F, Lowe CE, Szeszko JS, Hafler JP, Zeitels L, Yang JH, Vella A, Nutland S, Stevens HE, Schuilenburg H, Coleman G, Maisuria M, Meadows W, Smink LJ, Healy B, Burren OS, Lam AA, Ovington NR, Allen J, Adlem E, Leung HT, Wallace C, Howson JM, Guja C, Ionescu-Tîrgovişte C; Genetics of Type 1 Diabetes in Finland; Simmonds MJ, Heward JM, Gough SC; Wellcome Trust Case Control Consortium; Dunger DB, Wicker LS, Clayton DG. Todd JA, et al. Among authors: dunger db. Nat Genet. 2007 Jul;39(7):857-64. doi: 10.1038/ng2068. Epub 2007 Jun 6. Nat Genet. 2007. PMID: 17554260 Free PMC article.
Prevention of type 1 diabetes: what next?
Dunger DB, Todd JA. Dunger DB, et al. Lancet. 2008 Nov 15;372(9651):1710-1. doi: 10.1016/S0140-6736(08)61310-0. Epub 2008 Sep 22. Lancet. 2008. PMID: 18814907 No abstract available.
552 results