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Randomized trial of the anti-FGF23 antibody KRN23 in X-linked hypophosphatemia.
Carpenter TO, Imel EA, Ruppe MD, Weber TJ, Klausner MA, Wooddell MM, Kawakami T, Ito T, Zhang X, Humphrey J, Insogna KL, Peacock M. Carpenter TO, et al. Among authors: ito t. J Clin Invest. 2014 Apr;124(4):1587-97. doi: 10.1172/JCI72829. Epub 2014 Feb 24. J Clin Invest. 2014. PMID: 24569459 Free PMC article. Clinical Trial.
Prolonged Correction of Serum Phosphorus in Adults With X-Linked Hypophosphatemia Using Monthly Doses of KRN23.
Imel EA, Zhang X, Ruppe MD, Weber TJ, Klausner MA, Ito T, Vergeire M, Humphrey JS, Glorieux FH, Portale AA, Insogna K, Peacock M, Carpenter TO. Imel EA, et al. Among authors: ito t. J Clin Endocrinol Metab. 2015 Jul;100(7):2565-73. doi: 10.1210/jc.2015-1551. Epub 2015 Apr 28. J Clin Endocrinol Metab. 2015. PMID: 25919461 Free PMC article. Clinical Trial.
Pharmacokinetics and pharmacodynamics of a human monoclonal anti-FGF23 antibody (KRN23) in the first multiple ascending-dose trial treating adults with X-linked hypophosphatemia.
Zhang X, Imel EA, Ruppe MD, Weber TJ, Klausner MA, Ito T, Vergeire M, Humphrey J, Glorieux FH, Portale AA, Insogna K, Carpenter TO, Peacock M. Zhang X, et al. Among authors: ito t. J Clin Pharmacol. 2016 Feb;56(2):176-85. doi: 10.1002/jcph.570. Epub 2015 Aug 11. J Clin Pharmacol. 2016. PMID: 26073451 Free PMC article. Clinical Trial.
Mice with deficiency in Pcdh15, a gene associated with bipolar disorders, exhibit significantly elevated diurnal amplitudes of locomotion and body temperature.
Mori D, Inami C, Ikeda R, Sawahata M, Urata S, Yamaguchi ST, Kobayashi Y, Fujita K, Arioka Y, Okumura H, Kushima I, Kodama A, Suzuki T, Hirao T, Yoshimi A, Sobue A, Ito T, Noda Y, Mizoguchi H, Nagai T, Kaibuchi K, Okabe S, Nishiguchi K, Kume K, Yamada K, Ozaki N. Mori D, et al. Among authors: ito t. Transl Psychiatry. 2024 May 28;14(1):216. doi: 10.1038/s41398-024-02952-6. Transl Psychiatry. 2024. PMID: 38806495
Transient cerebral vasospasm and global amnesia following post-CT contrast.
Kiyoshige N, Watanabe K, Nishimura T, Ito T, Ishihara K, Yamada K. Kiyoshige N, et al. Among authors: ito t. Radiol Case Rep. 2024 May 17;19(8):3250-3253. doi: 10.1016/j.radcr.2024.04.079. eCollection 2024 Aug. Radiol Case Rep. 2024. PMID: 38800083 Free PMC article.
Sulfur metabolism as a new therapeutic target of heart failure.
Nishimura A, Tang X, Zhou L, Ito T, Kato Y, Nishida M. Nishimura A, et al. Among authors: ito t. J Pharmacol Sci. 2024 Jul;155(3):75-83. doi: 10.1016/j.jphs.2024.04.005. Epub 2024 Apr 23. J Pharmacol Sci. 2024. PMID: 38797536 Free article. Review.
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