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Complete response to induction therapy in patients with Myc-positive and double-hit non-Hodgkin lymphoma is associated with prolonged progression-free survival.
Cohen JB, Geyer SM, Lozanski G, Zhao W, Heerema NA, Hall NC, Nagar VA, Hemminger JA, Jones JA, Porcu P, Christian BA, Baiocchi RA, Maddocks KJ, Flynn JM, Devine SM, Blum KA. Cohen JB, et al. Among authors: christian ba. Cancer. 2014 Jun 1;120(11):1677-85. doi: 10.1002/cncr.28642. Epub 2014 Feb 27. Cancer. 2014. PMID: 24578014 Free PMC article.
Antibody therapy for chronic lymphocytic leukemia.
Christian BA, Lin TS. Christian BA, et al. Semin Hematol. 2008 Apr;45(2):95-103. doi: 10.1053/j.seminhematol.2008.02.001. Semin Hematol. 2008. PMID: 18381104 Free PMC article. Review.
Combination anti-CD74 (milatuzumab) and anti-CD20 (rituximab) monoclonal antibody therapy has in vitro and in vivo activity in mantle cell lymphoma.
Alinari L, Yu B, Christian BA, Yan F, Shin J, Lapalombella R, Hertlein E, Lustberg ME, Quinion C, Zhang X, Lozanski G, Muthusamy N, Prætorius-Ibba M, O'Connor OA, Goldenberg DM, Byrd JC, Blum KA, Baiocchi RA. Alinari L, et al. Among authors: christian ba. Blood. 2011 Apr 28;117(17):4530-41. doi: 10.1182/blood-2010-08-303354. Epub 2011 Jan 12. Blood. 2011. PMID: 21228331 Free PMC article.
Novel targeted therapies for mantle cell lymphoma.
Alinari L, Christian B, Baiocchi RA. Alinari L, et al. Oncotarget. 2012 Feb;3(2):203-11. doi: 10.18632/oncotarget.426. Oncotarget. 2012. PMID: 22361516 Free PMC article.
Flavopiridol can be safely administered using a pharmacologically derived schedule and demonstrates activity in relapsed and refractory non-Hodgkin's lymphoma.
Jones JA, Rupert AS, Poi M, Phelps MA, Andritsos L, Baiocchi R, Benson DM, Blum KA, Christian B, Flynn J, Penza S, Porcu P, Grever MR, Byrd JC. Jones JA, et al. Am J Hematol. 2014 Jan;89(1):19-24. doi: 10.1002/ajh.23568. Epub 2013 Sep 30. Am J Hematol. 2014. PMID: 23959599 Free PMC article. Clinical Trial.
Complex karyotype is associated with aggressive disease and shortened progression-free survival in patients with newly diagnosed mantle cell lymphoma.
Cohen JB, Ruppert AS, Heerema NA, Andritsos LA, Jones JA, Porcu P, Baiocchi R, Christian BA, Byrd JC, Flynn J, Penza S, Devine SM, Blum KA. Cohen JB, et al. Among authors: christian ba. Clin Lymphoma Myeloma Leuk. 2015 May;15(5):278-285.e1. doi: 10.1016/j.clml.2014.12.012. Epub 2014 Dec 31. Clin Lymphoma Myeloma Leuk. 2015. PMID: 25660723
The combination of milatuzumab, a humanized anti-CD74 antibody, and veltuzumab, a humanized anti-CD20 antibody, demonstrates activity in patients with relapsed and refractory B-cell non-Hodgkin lymphoma.
Christian BA, Poi M, Jones JA, Porcu P, Maddocks K, Flynn JM, Benson DM Jr, Phelps MA, Wei L, Byrd JC, Wegener WA, Goldenberg DM, Baiocchi RA, Blum KA. Christian BA, et al. Br J Haematol. 2015 Jun;169(5):701-10. doi: 10.1111/bjh.13354. Epub 2015 Apr 7. Br J Haematol. 2015. PMID: 25847298 Free PMC article. Clinical Trial.
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