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Genome-wide association study for circulating tissue plasminogen activator levels and functional follow-up implicates endothelial STXBP5 and STX2.
Huang J, Huffman JE, Yamakuchi M, Trompet S, Asselbergs FW, Sabater-Lleal M, Trégouët DA, Chen WM, Smith NL, Kleber ME, Shin SY, Becker DM, Tang W, Dehghan A, Johnson AD, Truong V, Folkersen L, Yang Q, Oudot-Mellkah T, Buckley BM, Moore JH, Williams FM, Campbell H, Silbernagel G, Vitart V, Rudan I, Tofler GH, Navis GJ, Destefano A, Wright AF, Chen MH, de Craen AJ, Worrall BB, Rudnicka AR, Rumley A, Bookman EB, Psaty BM, Chen F, Keene KL, Franco OH, Böhm BO, Uitterlinden AG, Carter AM, Jukema JW, Sattar N, Bis JC, Ikram MA; Cohorts for Heart and Aging Research in Genome Epidemiology (CHARGE) Consortium Neurology Working Group; Sale MM, McKnight B, Fornage M, Ford I, Taylor K, Slagboom PE, McArdle WL, Hsu FC, Franco-Cereceda A, Goodall AH, Yanek LR, Furie KL, Cushman M, Hofman A, Witteman JC, Folsom AR, Basu S, Matijevic N, van Gilst WH, Wilson JF, Westendorp RG, Kathiresan S, Reilly MP; CARDIoGRAM Consortium; Tracy RP, Polasek O, Winkelmann BR, Grant PJ, Hillege HL, Cambien F, Stott DJ, Lowe GD, Spector TD, Meigs JB, Marz W, Eriksson P, Becker LC, Morange PE, Soranzo N, Williams SM, Hayward C, van der Harst P, Hamsten A, Lowenstein CJ, Strachan DP, O'Donnell CJ; CHARGE Conso… See abstract for full author list ➔ Huang J, et al. Among authors: lowenstein cj. Arterioscler Thromb Vasc Biol. 2014 May;34(5):1093-101. doi: 10.1161/ATVBAHA.113.302088. Epub 2014 Feb 27. Arterioscler Thromb Vasc Biol. 2014. PMID: 24578379 Free PMC article.
Ceramide triggers Weibel-Palade body exocytosis.
Bhatia R, Matsushita K, Yamakuchi M, Morrell CN, Cao W, Lowenstein CJ. Bhatia R, et al. Among authors: lowenstein cj. Circ Res. 2004 Aug 6;95(3):319-24. doi: 10.1161/01.RES.0000136519.84279.7a. Epub 2004 Jun 24. Circ Res. 2004. PMID: 15217913
Regulation of Weibel-Palade body exocytosis.
Lowenstein CJ, Morrell CN, Yamakuchi M. Lowenstein CJ, et al. Trends Cardiovasc Med. 2005 Nov;15(8):302-8. doi: 10.1016/j.tcm.2005.09.005. Trends Cardiovasc Med. 2005. PMID: 16297768 Review.
Epigallocatechin gallate inhibits endothelial exocytosis.
Yamakuchi M, Bao C, Ferlito M, Lowenstein CJ. Yamakuchi M, et al. Among authors: lowenstein cj. Biol Chem. 2008 Jul;389(7):935-41. doi: 10.1515/BC.2008.095. Biol Chem. 2008. PMID: 18627310 Free PMC article.
miR-34a repression of SIRT1 regulates apoptosis.
Yamakuchi M, Ferlito M, Lowenstein CJ. Yamakuchi M, et al. Among authors: lowenstein cj. Proc Natl Acad Sci U S A. 2008 Sep 9;105(36):13421-6. doi: 10.1073/pnas.0801613105. Epub 2008 Aug 28. Proc Natl Acad Sci U S A. 2008. PMID: 18755897 Free PMC article.
MiR-34, SIRT1 and p53: the feedback loop.
Yamakuchi M, Lowenstein CJ. Yamakuchi M, et al. Among authors: lowenstein cj. Cell Cycle. 2009 Mar 1;8(5):712-5. doi: 10.4161/cc.8.5.7753. Epub 2009 Mar 2. Cell Cycle. 2009. PMID: 19221490
Aldosterone activates endothelial exocytosis.
Jeong Y, Chaupin DF, Matsushita K, Yamakuchi M, Cameron SJ, Morrell CN, Lowenstein CJ. Jeong Y, et al. Among authors: lowenstein cj. Proc Natl Acad Sci U S A. 2009 Mar 10;106(10):3782-7. doi: 10.1073/pnas.0804037106. Epub 2009 Feb 17. Proc Natl Acad Sci U S A. 2009. PMID: 19223584 Free PMC article.
168 results