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Activation induced deaminase C-terminal domain links DNA breaks to end protection and repair during class switch recombination.
Zahn A, Eranki AK, Patenaude AM, Methot SP, Fifield H, Cortizas EM, Foster P, Imai K, Durandy A, Larijani M, Verdun RE, Di Noia JM. Zahn A, et al. Among authors: patenaude am. Proc Natl Acad Sci U S A. 2014 Mar 18;111(11):E988-97. doi: 10.1073/pnas.1320486111. Epub 2014 Mar 3. Proc Natl Acad Sci U S A. 2014. PMID: 24591601 Free PMC article.
Roles for APRIN (PDS5B) in homologous recombination and in ovarian cancer prediction.
Couturier AM, Fleury H, Patenaude AM, Bentley VL, Rodrigue A, Coulombe Y, Niraj J, Pauty J, Berman JN, Dellaire G, Di Noia JM, Mes-Masson AM, Masson JY. Couturier AM, et al. Among authors: patenaude am. Nucleic Acids Res. 2016 Dec 15;44(22):10879-10897. doi: 10.1093/nar/gkw921. Epub 2016 Oct 24. Nucleic Acids Res. 2016. PMID: 27924011 Free PMC article.
A licensing step links AID to transcription elongation for mutagenesis in B cells.
Methot SP, Litzler LC, Subramani PG, Eranki AK, Fifield H, Patenaude AM, Gilmore JC, Santiago GE, Bagci H, Côté JF, Larijani M, Verdun RE, Di Noia JM. Methot SP, et al. Among authors: patenaude am. Nat Commun. 2018 Mar 28;9(1):1248. doi: 10.1038/s41467-018-03387-6. Nat Commun. 2018. PMID: 29593215 Free PMC article.
PRMT5 is essential for B cell development and germinal center dynamics.
Litzler LC, Zahn A, Meli AP, Hébert S, Patenaude AM, Methot SP, Sprumont A, Bois T, Kitamura D, Costantino S, King IL, Kleinman CL, Richard S, Di Noia JM. Litzler LC, et al. Among authors: patenaude am. Nat Commun. 2019 Jan 3;10(1):22. doi: 10.1038/s41467-018-07884-6. Nat Commun. 2019. PMID: 30604754 Free PMC article.
The uracil-DNA glycosylase UNG protects the fitness of normal and cancer B cells expressing AID.
Safavi S, Larouche A, Zahn A, Patenaude AM, Domanska D, Dionne K, Rognes T, Dingler F, Kang SK, Liu Y, Johnson N, Hébert J, Verdun RE, Rada CA, Vega F, Nilsen H, Di Noia JM. Safavi S, et al. Among authors: patenaude am. NAR Cancer. 2020 Aug 27;2(3):zcaa019. doi: 10.1093/narcan/zcaa019. eCollection 2020 Sep. NAR Cancer. 2020. PMID: 33554121 Free PMC article.
17 results