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Variants of CEP68 gene are associated with acute urticaria/angioedema induced by multiple non-steroidal anti-inflammatory drugs.
Cornejo-García JA, Flores C, Plaza-Serón MC, Acosta-Herrera M, Blanca-López N, Doña I, Torres MJ, Mayorga C, Guéant-Rodríguez RM, Ayuso P, Fernández J, Laguna JJ, Agúndez JA, García-Martín E, Guéant JL, Canto G, Blanca M. Cornejo-García JA, et al. Among authors: plaza seron mc. PLoS One. 2014 Mar 11;9(3):e90966. doi: 10.1371/journal.pone.0090966. eCollection 2014. PLoS One. 2014. PMID: 24618698 Free PMC article.
Polymorphisms in CEP68 gene associated with risk of immediate selective reactions to non-steroidal anti-inflammatory drugs.
Perkins JR, Acosta-Herrera M, Plaza-Serón MC, Jurado-Escobar R, Doña I, García-Martín E, Isidoro-García M, Bartra J, Ribas-Perez D, Mayorga C, Torres MJ, Flores C, Cornejo-García JA. Perkins JR, et al. Among authors: plaza seron mc. Pharmacogenomics J. 2019 Apr;19(2):191-199. doi: 10.1038/s41397-018-0038-0. Epub 2018 Aug 10. Pharmacogenomics J. 2019. PMID: 30093714
Asthma and allergic rhinitis associate with the rs2229542 variant that induces a p.Lys90Glu mutation and compromises AKR1B1 protein levels.
García-Martín E, Sánchez-Gómez FJ, Amo G, García Menaya J, Cordobés C, Ayuso P, Plaza Serón MC, Blanca M, Campo P, Esguevillas G, Pajares MA, G Agúndez JA, Pérez-Sala D. García-Martín E, et al. Among authors: plaza seron mc. Hum Mutat. 2018 Aug;39(8):1081-1091. doi: 10.1002/humu.23548. Epub 2018 May 25. Hum Mutat. 2018. PMID: 29726087 Free article.