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High-resolution antibody dynamics of vaccine-induced immune responses.
Laserson U, Vigneault F, Gadala-Maria D, Yaari G, Uduman M, Vander Heiden JA, Kelton W, Taek Jung S, Liu Y, Laserson J, Chari R, Lee JH, Bachelet I, Hickey B, Lieberman-Aiden E, Hanczaruk B, Simen BB, Egholm M, Koller D, Georgiou G, Kleinstein SH, Church GM. Laserson U, et al. Among authors: kleinstein sh. Proc Natl Acad Sci U S A. 2014 Apr 1;111(13):4928-33. doi: 10.1073/pnas.1323862111. Epub 2014 Mar 17. Proc Natl Acad Sci U S A. 2014. PMID: 24639495 Free PMC article.
Detecting selection in immunoglobulin sequences.
Uduman M, Yaari G, Hershberg U, Stern JA, Shlomchik MJ, Kleinstein SH. Uduman M, et al. Among authors: kleinstein sh. Nucleic Acids Res. 2011 Jul;39(Web Server issue):W499-504. doi: 10.1093/nar/gkr413. Epub 2011 Jun 10. Nucleic Acids Res. 2011. PMID: 21665923 Free PMC article.
Cell subset prediction for blood genomic studies.
Bolen CR, Uduman M, Kleinstein SH. Bolen CR, et al. Among authors: kleinstein sh. BMC Bioinformatics. 2011 Jun 24;12:258. doi: 10.1186/1471-2105-12-258. BMC Bioinformatics. 2011. PMID: 21702940 Free PMC article.
The effects of somatic hypermutation on neutralization and binding in the PGT121 family of broadly neutralizing HIV antibodies.
Sok D, Laserson U, Laserson J, Liu Y, Vigneault F, Julien JP, Briney B, Ramos A, Saye KF, Le K, Mahan A, Wang S, Kardar M, Yaari G, Walker LM, Simen BB, St John EP, Chan-Hui PY, Swiderek K, Kleinstein SH, Alter G, Seaman MS, Chakraborty AK, Koller D, Wilson IA, Church GM, Burton DR, Poignard P. Sok D, et al. Among authors: kleinstein sh. PLoS Pathog. 2013;9(11):e1003754. doi: 10.1371/journal.ppat.1003754. Epub 2013 Nov 21. PLoS Pathog. 2013. PMID: 24278016 Free PMC article. Clinical Trial.
Models of somatic hypermutation targeting and substitution based on synonymous mutations from high-throughput immunoglobulin sequencing data.
Yaari G, Vander Heiden JA, Uduman M, Gadala-Maria D, Gupta N, Stern JN, O'Connor KC, Hafler DA, Laserson U, Vigneault F, Kleinstein SH. Yaari G, et al. Among authors: kleinstein sh. Front Immunol. 2013 Nov 15;4:358. doi: 10.3389/fimmu.2013.00358. eCollection 2013. Front Immunol. 2013. PMID: 24298272 Free PMC article.
184 results