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A new model for an etiology of rheumatoid arthritis: smoking may trigger HLA-DR (shared epitope)-restricted immune reactions to autoantigens modified by citrullination.
Klareskog L, Stolt P, Lundberg K, Källberg H, Bengtsson C, Grunewald J, Rönnelid J, Harris HE, Ulfgren AK, Rantapää-Dahlqvist S, Eklund A, Padyukov L, Alfredsson L. Klareskog L, et al. Among authors: padyukov l. Arthritis Rheum. 2006 Jan;54(1):38-46. doi: 10.1002/art.21575. Arthritis Rheum. 2006. PMID: 16385494 Free article.
Gene-gene and gene-environment interactions involving HLA-DRB1, PTPN22, and smoking in two subsets of rheumatoid arthritis.
Kallberg H, Padyukov L, Plenge RM, Ronnelid J, Gregersen PK, van der Helm-van Mil AH, Toes RE, Huizinga TW, Klareskog L, Alfredsson L; Epidemiological Investigation of Rheumatoid Arthritis study group. Kallberg H, et al. Among authors: padyukov l. Am J Hum Genet. 2007 May;80(5):867-75. doi: 10.1086/516736. Epub 2007 Apr 2. Am J Hum Genet. 2007. PMID: 17436241 Free PMC article.
Different patterns of associations with anti-citrullinated protein antibody-positive and anti-citrullinated protein antibody-negative rheumatoid arthritis in the extended major histocompatibility complex region.
Ding B, Padyukov L, Lundström E, Seielstad M, Plenge RM, Oksenberg JR, Gregersen PK, Alfredsson L, Klareskog L. Ding B, et al. Among authors: padyukov l. Arthritis Rheum. 2009 Jan;60(1):30-8. doi: 10.1002/art.24135. Arthritis Rheum. 2009. PMID: 19116921 Free PMC article.
288 results