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An Intrinsically Disordered APLF Links Ku, DNA-PKcs, and XRCC4-DNA Ligase IV in an Extended Flexible Non-homologous End Joining Complex.
Hammel M, Yu Y, Radhakrishnan SK, Chokshi C, Tsai MS, Matsumoto Y, Kuzdovich M, Remesh SG, Fang S, Tomkinson AE, Lees-Miller SP, Tainer JA. Hammel M, et al. Among authors: radhakrishnan sk. J Biol Chem. 2016 Dec 30;291(53):26987-27006. doi: 10.1074/jbc.M116.751867. Epub 2016 Nov 14. J Biol Chem. 2016. PMID: 27875301 Free PMC article.
Induction of microRNA-1 by myocardin in smooth muscle cells inhibits cell proliferation.
Chen J, Yin H, Jiang Y, Radhakrishnan SK, Huang ZP, Li J, Shi Z, Kilsdonk EP, Gui Y, Wang DZ, Zheng XL. Chen J, et al. Among authors: radhakrishnan sk. Arterioscler Thromb Vasc Biol. 2011 Feb;31(2):368-75. doi: 10.1161/ATVBAHA.110.218149. Epub 2010 Nov 4. Arterioscler Thromb Vasc Biol. 2011. PMID: 21051663 Free PMC article.
Targeting of SUMOylation leads to cBAF complex stabilization and disruption of the SS18::SSX transcriptome in Synovial Sarcoma.
Floros KV, Fairchild CK, Li J, Zhang K, Roberts JL, Kurupi R, Hu B, Kraskauskiene V, Hosseini N, Shen S, Inge MM, Smith-Fry K, Li L, Sotiriou A, Dalton KM, Jose A, Abdelfadiel EI, Xing Y, Hill RD, Slaughter JM, Shende M, Lorenz MR, Hinojosa MR, Belvin BR, Lai Z, Boikos SA, Stamatouli AM, Lewis JP, Manjili MH, Valerie K, Li R, Banito A, Poklepovic A, Koblinski JE, Siggers T, Dozmorov MG, Jones KB, Radhakrishnan SK, Faber AC. Floros KV, et al. Among authors: radhakrishnan sk. bioRxiv [Preprint]. 2024 Apr 27:2024.04.25.591023. doi: 10.1101/2024.04.25.591023. bioRxiv. 2024. PMID: 38712286 Free PMC article. Preprint.
Transcription factor Nrf1 regulates proteotoxic stress-induced autophagy.
Ward MA, Vangala JR, Kamber Kaya HE, Byers HA, Hosseini N, Diaz A, Cuervo AM, Kaushik S, Radhakrishnan SK. Ward MA, et al. Among authors: radhakrishnan sk. J Cell Biol. 2024 Jun 3;223(6):e202306150. doi: 10.1083/jcb.202306150. Epub 2024 Apr 24. J Cell Biol. 2024. PMID: 38656405 Free PMC article.
Cullin-RING ligases employ geometrically optimized catalytic partners for substrate targeting.
Li J, Purser N, Liwocha J, Scott DC, Byers HA, Steigenberger B, Hill S, Tripathi-Giesgen I, Hinkle T, Hansen FM, Prabu JR, Radhakrishnan SK, Kirkpatrick DS, Reichermeier KM, Schulman BA, Kleiger G. Li J, et al. Among authors: radhakrishnan sk. Mol Cell. 2024 Apr 4;84(7):1304-1320.e16. doi: 10.1016/j.molcel.2024.01.022. Epub 2024 Feb 20. Mol Cell. 2024. PMID: 38382526 Free PMC article.
242 results