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Increased susceptibility to hyperoxic lung injury and alveolar simplification in newborn rats by prenatal administration of benzo[a]pyrene.
Thakur VS, Liang YW, Lingappan K, Jiang W, Wang L, Barrios R, Zhou G, Guntupalli B, Shivanna B, Maturu P, Welty SE, Moorthy B, Couroucli XI. Thakur VS, et al. Among authors: welty se. Toxicol Lett. 2014 Oct 15;230(2):322-32. doi: 10.1016/j.toxlet.2014.03.006. Epub 2014 Mar 19. Toxicol Lett. 2014. PMID: 24657529 Free PMC article.
Disruption of the Ah receptor gene alters the susceptibility of mice to oxygen-mediated regulation of pulmonary and hepatic cytochromes P4501A expression and exacerbates hyperoxic lung injury.
Jiang W, Welty SE, Couroucli XI, Barrios R, Kondraganti SR, Muthiah K, Yu L, Avery SE, Moorthy B. Jiang W, et al. Among authors: welty se. J Pharmacol Exp Ther. 2004 Aug;310(2):512-9. doi: 10.1124/jpet.103.059766. Epub 2004 May 3. J Pharmacol Exp Ther. 2004. PMID: 15123765
Mice deficient in the gene for cytochrome P450 (CYP)1A1 are more susceptible than wild-type to hyperoxic lung injury: evidence for protective role of CYP1A1 against oxidative stress.
Lingappan K, Jiang W, Wang L, Wang G, Couroucli XI, Shivanna B, Welty SE, Barrios R, Khan MF, Nebert DW, Roberts LJ, Moorthy B. Lingappan K, et al. Among authors: welty se. Toxicol Sci. 2014 Sep;141(1):68-77. doi: 10.1093/toxsci/kfu106. Epub 2014 Jun 3. Toxicol Sci. 2014. PMID: 24893714 Free PMC article.
Aryl hydrocarbon receptor is necessary to protect fetal human pulmonary microvascular endothelial cells against hyperoxic injury: Mechanistic roles of antioxidant enzymes and RelB.
Zhang S, Patel A, Chu C, Jiang W, Wang L, Welty SE, Moorthy B, Shivanna B. Zhang S, et al. Among authors: welty se. Toxicol Appl Pharmacol. 2015 Jul 15;286(2):92-101. doi: 10.1016/j.taap.2015.03.023. Epub 2015 Mar 29. Toxicol Appl Pharmacol. 2015. PMID: 25831079 Free PMC article.
Gene Expression Profiling Identifies Cell Proliferation and Inflammation as the Predominant Pathways Regulated by Aryl Hydrocarbon Receptor in Primary Human Fetal Lung Cells Exposed to Hyperoxia.
Shivanna B, Maity S, Zhang S, Patel A, Jiang W, Wang L, Welty SE, Belmont J, Coarfa C, Moorthy B. Shivanna B, et al. Among authors: welty se. Toxicol Sci. 2016 Jul;152(1):155-68. doi: 10.1093/toxsci/kfw071. Epub 2016 Apr 21. Toxicol Sci. 2016. PMID: 27103661 Free PMC article.
143 results