Thomas E - Search Results

1

Physiological and genetic analysis of multiple sodium channel variants in a model of genetic absence epilepsy.

Oliva MK, McGarr TC, Beyer BJ, Gazina E, Kaplan DI, Cordeiro L, Thomas E, Dib-Hajj SD, Waxman SG, Frankel WN, Petrou S. Oliva MK, et al. Among authors: thomas e. Neurobiol Dis. 2014 Jul;67:180-90. doi: 10.1016/j.nbd.2014.03.007. Epub 2014 Mar 19. Neurobiol Dis. 2014. PMID: 24657915 Free PMC article.

2

Differential expression of exon 5 splice variants of sodium channel alpha subunit mRNAs in the developing mouse brain.

Gazina EV, Richards KL, Mokhtar MB, Thomas EA, Reid CA, Petrou S. Gazina EV, et al. Among authors: thomas ea. Neuroscience. 2010 Mar 10;166(1):195-200. doi: 10.1016/j.neuroscience.2009.12.011. Epub 2009 Dec 17. Neuroscience. 2010. PMID: 20006674

3

A childhood epilepsy mutation reveals a role for developmentally regulated splicing of a sodium channel.

Xu R, Thomas EA, Jenkins M, Gazina EV, Chiu C, Heron SE, Mulley JC, Scheffer IE, Berkovic SF, Petrou S. Xu R, et al. Among authors: thomas ea. Mol Cell Neurosci. 2007 Jun;35(2):292-301. doi: 10.1016/j.mcn.2007.03.003. Epub 2007 Mar 13. Mol Cell Neurosci. 2007. PMID: 17467289

4

Mossy fiber sprouting interacts with sodium channel mutations to increase dentate gyrus excitability.

Thomas EA, Reid CA, Petrou S. Thomas EA, et al. Epilepsia. 2010 Jan;51(1):136-45. doi: 10.1111/j.1528-1167.2009.02202.x. Epub 2009 Aug 13. Epilepsia. 2010. PMID: 19682031 Free article.

5

Heat opens axon initial segment sodium channels: a febrile seizure mechanism?

Thomas EA, Hawkins RJ, Richards KL, Xu R, Gazina EV, Petrou S. Thomas EA, et al. Ann Neurol. 2009 Aug;66(2):219-26. doi: 10.1002/ana.21712. Ann Neurol. 2009. PMID: 19743470

6

Computational analysis of the R85C and R85H epilepsy mutations in Na+ channel beta1 subunits.

Thomas EA, Xu R, Petrou S. Thomas EA, et al. Neuroscience. 2007 Jul 29;147(4):1034-46. doi: 10.1016/j.neuroscience.2007.05.010. Epub 2007 Jul 2. Neuroscience. 2007. PMID: 17604911

7

Generalized epilepsy with febrile seizures plus-associated sodium channel beta1 subunit mutations severely reduce beta subunit-mediated modulation of sodium channel function.

Xu R, Thomas EA, Gazina EV, Richards KL, Quick M, Wallace RH, Harkin LA, Heron SE, Berkovic SF, Scheffer IE, Mulley JC, Petrou S. Xu R, et al. Among authors: thomas ea. Neuroscience. 2007 Aug 10;148(1):164-74. doi: 10.1016/j.neuroscience.2007.05.038. Epub 2007 Jul 12. Neuroscience. 2007. PMID: 17629415

8

Prediction by modeling that epilepsy may be caused by very small functional changes in ion channels.

Thomas EA, Reid CA, Berkovic SF, Petrou S. Thomas EA, et al. Arch Neurol. 2009 Oct;66(10):1225-32. doi: 10.1001/archneurol.2009.219. Arch Neurol. 2009. PMID: 19822777

9

Network-specific mechanisms may explain the paradoxical effects of carbamazepine and phenytoin.

Thomas EA, Petrou S. Thomas EA, et al. Epilepsia. 2013 Jul;54(7):1195-202. doi: 10.1111/epi.12172. Epub 2013 Apr 8. Epilepsia. 2013. PMID: 23566163 Free article.

10

Axon initial segment structural plasticity in animal models of genetic and acquired epilepsy.

Harty RC, Kim TH, Thomas EA, Cardamone L, Jones NC, Petrou S, Wimmer VC. Harty RC, et al. Epilepsy Res. 2013 Aug;105(3):272-9. doi: 10.1016/j.eplepsyres.2013.03.004. Epub 2013 Apr 17. Epilepsy Res. 2013. PMID: 23602553

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