Simonsen A - Search Results

1

Structural determinants in GABARAP required for the selective binding and recruitment of ALFY to LC3B-positive structures.

Lystad AH, Ichimura Y, Takagi K, Yang Y, Pankiv S, Kanegae Y, Kageyama S, Suzuki M, Saito I, Mizushima T, Komatsu M, Simonsen A. Lystad AH, et al. Among authors: simonsen a. EMBO Rep. 2014 May;15(5):557-65. doi: 10.1002/embr.201338003. Epub 2014 Mar 25. EMBO Rep. 2014. PMID: 24668264 Free PMC article.

2

Alfy, a novel FYVE-domain-containing protein associated with protein granules and autophagic membranes.

Simonsen A, Birkeland HC, Gillooly DJ, Mizushima N, Kuma A, Yoshimori T, Slagsvold T, Brech A, Stenmark H. Simonsen A, et al. J Cell Sci. 2004 Aug 15;117(Pt 18):4239-51. doi: 10.1242/jcs.01287. Epub 2004 Aug 3. J Cell Sci. 2004. PMID: 15292400

3

p62/SQSTM1 and ALFY interact to facilitate the formation of p62 bodies/ALIS and their degradation by autophagy.

Clausen TH, Lamark T, Isakson P, Finley K, Larsen KB, Brech A, Øvervatn A, Stenmark H, Bjørkøy G, Simonsen A, Johansen T. Clausen TH, et al. Among authors: simonsen a. Autophagy. 2010 Apr;6(3):330-44. doi: 10.4161/auto.6.3.11226. Epub 2010 Apr 11. Autophagy. 2010. PMID: 20168092

4

The selective macroautophagic degradation of aggregated proteins requires the PI3P-binding protein Alfy.

Filimonenko M, Isakson P, Finley KD, Anderson M, Jeong H, Melia TJ, Bartlett BJ, Myers KM, Birkeland HC, Lamark T, Krainc D, Brech A, Stenmark H, Simonsen A, Yamamoto A. Filimonenko M, et al. Among authors: simonsen a. Mol Cell. 2010 Apr 23;38(2):265-79. doi: 10.1016/j.molcel.2010.04.007. Mol Cell. 2010. PMID: 20417604 Free PMC article.

5

The role of ALFY in selective autophagy.

Isakson P, Holland P, Simonsen A. Isakson P, et al. Among authors: simonsen a. Cell Death Differ. 2013 Jan;20(1):12-20. doi: 10.1038/cdd.2012.66. Epub 2012 Jun 1. Cell Death Differ. 2013. PMID: 22653340 Free PMC article. Review.

6

The arsenic-based cure of acute promyelocytic leukemia promotes cytoplasmic sequestration of PML and PML/RARA through inhibition of PML body recycling.

Lång E, Grudic A, Pankiv S, Bruserud O, Simonsen A, Bjerkvig R, Bjørås M, Bøe SO. Lång E, et al. Among authors: simonsen a. Blood. 2012 Jul 26;120(4):847-57. doi: 10.1182/blood-2011-10-388496. Epub 2012 Jun 12. Blood. 2012. PMID: 22692509 Free article.

7

Receptor protein complexes are in control of autophagy.

Mijaljica D, Nazarko TY, Brumell JH, Huang WP, Komatsu M, Prescott M, Simonsen A, Yamamoto A, Zhang H, Klionsky DJ, Devenish RJ. Mijaljica D, et al. Among authors: simonsen a. Autophagy. 2012 Nov;8(11):1701-5. doi: 10.4161/auto.21332. Epub 2012 Aug 9. Autophagy. 2012. PMID: 22874568 Free PMC article.

8

Selective types of autophagy.

Reggiori F, Komatsu M, Finley K, Simonsen A. Reggiori F, et al. Among authors: simonsen a. Int J Cell Biol. 2012;2012:156272. doi: 10.1155/2012/156272. Epub 2012 Aug 21. Int J Cell Biol. 2012. PMID: 22956958 Free PMC article. No abstract available.

9

TRAF6 mediates ubiquitination of KIF23/MKLP1 and is required for midbody ring degradation by selective autophagy.

Isakson P, Lystad AH, Breen K, Koster G, Stenmark H, Simonsen A. Isakson P, et al. Among authors: simonsen a. Autophagy. 2013 Dec;9(12):1955-64. doi: 10.4161/auto.26085. Autophagy. 2013. PMID: 24128730

10

Assays to monitor aggrephagy.

Lystad AH, Simonsen A. Lystad AH, et al. Among authors: simonsen a. Methods. 2015 Mar;75:112-9. doi: 10.1016/j.ymeth.2014.12.019. Epub 2014 Dec 31. Methods. 2015. PMID: 25555675

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