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Constitutional and somatic rearrangement of chromosome 21 in acute lymphoblastic leukaemia.
Li Y, Schwab C, Ryan S, Papaemmanuil E, Robinson HM, Jacobs P, Moorman AV, Dyer S, Borrow J, Griffiths M, Heerema NA, Carroll AJ, Talley P, Bown N, Telford N, Ross FM, Gaunt L, McNally RJQ, Young BD, Sinclair P, Rand V, Teixeira MR, Joseph O, Robinson B, Maddison M, Dastugue N, Vandenberghe P, Stephens PJ, Cheng J, Van Loo P, Stratton MR, Campbell PJ, Harrison CJ. Li Y, et al. Among authors: sinclair p. Nature. 2014 Apr 3;508(7494):98-102. doi: 10.1038/nature13115. Epub 2014 Mar 23. Nature. 2014. PMID: 24670643 Free PMC article.
Genomic characterization implicates iAMP21 as a likely primary genetic event in childhood B-cell precursor acute lymphoblastic leukemia.
Rand V, Parker H, Russell LJ, Schwab C, Ensor H, Irving J, Jones L, Masic D, Minto L, Morrison H, Ryan S, Robinson H, Sinclair P, Moorman AV, Strefford JC, Harrison CJ. Rand V, et al. Among authors: sinclair p. Blood. 2011 Jun 23;117(25):6848-55. doi: 10.1182/blood-2011-01-329961. Epub 2011 Apr 28. Blood. 2011. PMID: 21527530 Free article.
Dynamic clonal progression in xenografts of acute lymphoblastic leukemia with intrachromosomal amplification of chromosome 21.
Sinclair PB, Blair HH, Ryan SL, Buechler L, Cheng J, Clayton J, Hanna R, Hollern S, Hawking Z, Bashton M, Schwab CJ, Jones L, Russell LJ, Marr H, Carey P, Halsey C, Heidenreich O, Moorman AV, Harrison CJ. Sinclair PB, et al. Haematologica. 2018 Apr;103(4):634-644. doi: 10.3324/haematol.2017.172304. Epub 2018 Feb 15. Haematologica. 2018. PMID: 29449437 Free PMC article.
The role of the RAS pathway in iAMP21-ALL.
Ryan SL, Matheson E, Grossmann V, Sinclair P, Bashton M, Schwab C, Towers W, Partington M, Elliott A, Minto L, Richardson S, Rahman T, Keavney B, Skinner R, Bown N, Haferlach T, Vandenberghe P, Haferlach C, Santibanez-Koref M, Moorman AV, Kohlmann A, Irving JA, Harrison CJ. Ryan SL, et al. Among authors: sinclair p. Leukemia. 2016 Sep;30(9):1824-31. doi: 10.1038/leu.2016.80. Epub 2016 Apr 22. Leukemia. 2016. PMID: 27168466 Free PMC article.
The pre-B-cell receptor checkpoint in acute lymphoblastic leukaemia.
Eswaran J, Sinclair P, Heidenreich O, Irving J, Russell LJ, Hall A, Calado DP, Harrison CJ, Vormoor J. Eswaran J, et al. Among authors: sinclair p. Leukemia. 2015 Aug;29(8):1623-31. doi: 10.1038/leu.2015.113. Epub 2015 May 6. Leukemia. 2015. PMID: 25943180 Review.
511 results