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Engineering of a novel anti-CD40L domain antibody for treatment of autoimmune diseases.
Xie JH, Yamniuk AP, Borowski V, Kuhn R, Susulic V, Rex-Rabe S, Yang X, Zhou X, Zhang Y, Gillooly K, Brosius R, Ravishankar R, Waggie K, Mink K, Price L, Rehfuss R, Tamura J, An Y, Cheng L, Abramczyk B, Ignatovich O, Drew P, Grant S, Bryson JW, Suchard S, Salter-Cid L, Nadler S, Suri A. Xie JH, et al. Among authors: abramczyk b. J Immunol. 2014 May 1;192(9):4083-92. doi: 10.4049/jimmunol.1303239. Epub 2014 Mar 26. J Immunol. 2014. PMID: 24670803
Exploration of macrocyclic peptide binders to the extracellular CRD domain of human receptor tyrosine kinase-like orphan receptor 1 (ROR1).
Qiao JX, Witmer MR, Lee V, Wang TC, Reid PC, Arioka Y, Farr G, Hill-Drzewi M, Schweizer L, Yamniuk A, Cheng L, Abramczyk B, Corbett M, Calambur D, Szapiel N, Ryseck R, Ponath P, Poss MA, Carter P. Qiao JX, et al. Among authors: abramczyk b. Bioorg Med Chem Lett. 2024 Jan 15;98:129589. doi: 10.1016/j.bmcl.2023.129589. Epub 2023 Dec 13. Bioorg Med Chem Lett. 2024. PMID: 38097140
Structures of adnectin/protein complexes reveal an expanded binding footprint.
Ramamurthy V, Krystek SR Jr, Bush A, Wei A, Emanuel SL, Das Gupta R, Janjua A, Cheng L, Murdock M, Abramczyk B, Cohen D, Lin Z, Morin P, Davis JH, Dabritz M, McLaughlin DC, Russo KA, Chao G, Wright MC, Jenny VA, Engle LJ, Furfine E, Sheriff S. Ramamurthy V, et al. Among authors: abramczyk b. Structure. 2012 Feb 8;20(2):259-69. doi: 10.1016/j.str.2011.11.016. Structure. 2012. PMID: 22325775 Free article.
17 results