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Engineering of a novel anti-CD40L domain antibody for treatment of autoimmune diseases.
J Immunol. 2014 May 1;192(9):4083-92. doi: 10.4049/jimmunol.1303239. Epub 2014 Mar 26.
J Immunol. 2014.
PMID: 24670803
A monovalent anti-human CD28 domain antibody antagonist: preclinical efficacy and safety.
Suchard SJ, Davis PM, Kansal S, Stetsko DK, Brosius R, Tamura J, Schneeweis L, Bryson J, Salcedo T, Wang H, Yang Z, Fleener CA, Ignatovich O, Plummer C, Grant S, Nadler SG.
Suchard SJ, et al. Among authors: brosius r.
J Immunol. 2013 Nov 1;191(9):4599-610. doi: 10.4049/jimmunol.1300470. Epub 2013 Sep 30.
J Immunol. 2013.
PMID: 24081989
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Effect of a single amino acid mutation on the activating and immunosuppressive properties of a "humanized" OKT3 monoclonal antibody.
Alegre ML, Collins AM, Pulito VL, Brosius RA, Olson WC, Zivin RA, Knowles R, Thistlethwaite JR, Jolliffe LK, Bluestone JA.
Alegre ML, et al. Among authors: brosius ra.
J Immunol. 1992 Jun 1;148(11):3461-8.
J Immunol. 1992.
PMID: 1534096
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Efficacy and tolerability of lasmiditan, an oral 5-HT(1F) receptor agonist, for the acute treatment of migraine: a phase 2 randomised, placebo-controlled, parallel-group, dose-ranging study.
Färkkilä M, Diener HC, Géraud G, Láinez M, Schoenen J, Harner N, Pilgrim A, Reuter U; COL MIG-202 study group.
Färkkilä M, et al.
Lancet Neurol. 2012 May;11(5):405-13. doi: 10.1016/S1474-4422(12)70047-9. Epub 2012 Mar 28.
Lancet Neurol. 2012.
PMID: 22459549
Clinical Trial.
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Drug-eluting stents: sirolimus and paclitaxel differentially affect cultured cells and injured arteries.
Parry TJ, Brosius R, Thyagarajan R, Carter D, Argentieri D, Falotico R, Siekierka J.
Parry TJ, et al. Among authors: brosius r.
Eur J Pharmacol. 2005 Nov 7;524(1-3):19-29. doi: 10.1016/j.ejphar.2005.09.042. Epub 2005 Nov 3.
Eur J Pharmacol. 2005.
PMID: 16271360
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Nitroarylhydroxymethylphosphonic acids as inhibitors of CD45.
Beers SA, Malloy EA, Wu W, Wachter MP, Gunnia U, Cavender D, Harris C, Davis J, Brosius R, Pellegrino-Gensey JL, Siekierka J.
Beers SA, et al. Among authors: brosius r.
Bioorg Med Chem. 1997 Dec;5(12):2203-11. doi: 10.1016/s0968-0896(97)00174-0.
Bioorg Med Chem. 1997.
PMID: 9459018
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