López-Otín C - Search Results

1

POT1 loss-of-function variants predispose to familial melanoma.

Robles-Espinoza CD, Harland M, Ramsay AJ, Aoude LG, Quesada V, Ding Z, Pooley KA, Pritchard AL, Tiffen JC, Petljak M, Palmer JM, Symmons J, Johansson P, Stark MS, Gartside MG, Snowden H, Montgomery GW, Martin NG, Liu JZ, Choi J, Makowski M, Brown KM, Dunning AM, Keane TM, López-Otín C, Gruis NA, Hayward NK, Bishop DT, Newton-Bishop JA, Adams DJ. Robles-Espinoza CD, et al. Nat Genet. 2014 May;46(5):478-481. doi: 10.1038/ng.2947. Epub 2014 Mar 30. Nat Genet. 2014. PMID: 24686849 Free PMC article.

2

Identification and enzymatic characterization of two diverging murine counterparts of human interstitial collagenase (MMP-1) expressed at sites of embryo implantation.

Balbín M, Fueyo A, Knäuper V, López JM, Alvarez J, Sánchez LM, Quesada V, Bordallo J, Murphy G, López-Otín C. Balbín M, et al. J Biol Chem. 2001 Mar 30;276(13):10253-62. doi: 10.1074/jbc.M009586200. Epub 2000 Dec 11. J Biol Chem. 2001. PMID: 11113146 Free article.

3

Cloning, expression analysis, and structural characterization of seven novel human ADAMTSs, a family of metalloproteinases with disintegrin and thrombospondin-1 domains.

Cal S, Obaya AJ, Llamazares M, Garabaya C, Quesada V, López-Otín C. Cal S, et al. Gene. 2002 Jan 23;283(1-2):49-62. doi: 10.1016/s0378-1119(01)00861-7. Gene. 2002. PMID: 11867212

4

Structural and enzymatic characterization of Drosophila Dm2-MMP, a membrane-bound matrix metalloproteinase with tissue-specific expression.

Llano E, Adam G, Pendás AM, Quesada V, Sánchez LM, Santamariá I, Noselli S, López-Otín C. Llano E, et al. J Biol Chem. 2002 Jun 28;277(26):23321-9. doi: 10.1074/jbc.M200121200. Epub 2002 Apr 19. J Biol Chem. 2002. PMID: 11967260 Free article.

5

Matriptase-2, a membrane-bound mosaic serine proteinase predominantly expressed in human liver and showing degrading activity against extracellular matrix proteins.

Velasco G, Cal S, Quesada V, Sánchez LM, López-Otín C. Velasco G, et al. J Biol Chem. 2002 Oct 4;277(40):37637-46. doi: 10.1074/jbc.M203007200. Epub 2002 Jul 30. J Biol Chem. 2002. PMID: 12149247 Free article. Retracted.

6

Human autophagins, a family of cysteine proteinases potentially implicated in cell degradation by autophagy.

Mariño G, Uría JA, Puente XS, Quesada V, Bordallo J, López-Otín C. Mariño G, et al. J Biol Chem. 2003 Feb 7;278(6):3671-8. doi: 10.1074/jbc.M208247200. Epub 2002 Nov 21. J Biol Chem. 2003. PMID: 12446702 Free article. Retracted.

7

Identification and characterization of ADAMTS-20 defines a novel subfamily of metalloproteinases-disintegrins with multiple thrombospondin-1 repeats and a unique GON domain.

Llamazares M, Cal S, Quesada V, López-Otín C. Llamazares M, et al. J Biol Chem. 2003 Apr 11;278(15):13382-9. doi: 10.1074/jbc.M211900200. Epub 2003 Jan 31. J Biol Chem. 2003. PMID: 12562771 Free article.

8

Human and mouse proteases: a comparative genomic approach.

Puente XS, Sánchez LM, Overall CM, López-Otín C. Puente XS, et al. Nat Rev Genet. 2003 Jul;4(7):544-58. doi: 10.1038/nrg1111. Nat Rev Genet. 2003. PMID: 12838346 Review.

9

Polyserase-I, a human polyprotease with the ability to generate independent serine protease domains from a single translation product.

Cal S, Quesada V, Garabaya C, Lopez-Otin C. Cal S, et al. Proc Natl Acad Sci U S A. 2003 Aug 5;100(16):9185-90. doi: 10.1073/pnas.1633392100. Epub 2003 Jul 28. Proc Natl Acad Sci U S A. 2003. PMID: 12886014 Free PMC article.

10

Loss of collagenase-2 confers increased skin tumor susceptibility to male mice.

Balbín M, Fueyo A, Tester AM, Pendás AM, Pitiot AS, Astudillo A, Overall CM, Shapiro SD, López-Otín C. Balbín M, et al. Nat Genet. 2003 Nov;35(3):252-7. doi: 10.1038/ng1249. Epub 2003 Sep 28. Nat Genet. 2003. PMID: 14517555

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