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Hypermethylation in the ZBTB20 gene is associated with major depressive disorder.
Davies MN, Krause L, Bell JT, Gao F, Ward KJ, Wu H, Lu H, Liu Y, Tsai PC, Collier DA, Murphy T, Dempster E, Mill J; UK Brain Expression Consortium; Battle A, Mostafavi S, Zhu X, Henders A, Byrne E, Wray NR, Martin NG, Spector TD, Wang J. Davies MN, et al. Among authors: spector td. Genome Biol. 2014 Apr 2;15(4):R56. doi: 10.1186/gb-2014-15-4-r56. Genome Biol. 2014. PMID: 24694013 Free PMC article.
A twin approach to unraveling epigenetics.
Bell JT, Spector TD. Bell JT, et al. Among authors: spector td. Trends Genet. 2011 Mar;27(3):116-25. doi: 10.1016/j.tig.2010.12.005. Epub 2011 Jan 21. Trends Genet. 2011. PMID: 21257220 Free PMC article. Review.
Epigenome-wide scans identify differentially methylated regions for age and age-related phenotypes in a healthy ageing population.
Bell JT, Tsai PC, Yang TP, Pidsley R, Nisbet J, Glass D, Mangino M, Zhai G, Zhang F, Valdes A, Shin SY, Dempster EL, Murray RM, Grundberg E, Hedman AK, Nica A, Small KS; MuTHER Consortium; Dermitzakis ET, McCarthy MI, Mill J, Spector TD, Deloukas P. Bell JT, et al. Among authors: spector td. PLoS Genet. 2012;8(4):e1002629. doi: 10.1371/journal.pgen.1002629. Epub 2012 Apr 19. PLoS Genet. 2012. PMID: 22532803 Free PMC article.
Meta-analysis of telomere length in 19,713 subjects reveals high heritability, stronger maternal inheritance and a paternal age effect.
Broer L, Codd V, Nyholt DR, Deelen J, Mangino M, Willemsen G, Albrecht E, Amin N, Beekman M, de Geus EJ, Henders A, Nelson CP, Steves CJ, Wright MJ, de Craen AJ, Isaacs A, Matthews M, Moayyeri A, Montgomery GW, Oostra BA, Vink JM, Spector TD, Slagboom PE, Martin NG, Samani NJ, van Duijn CM, Boomsma DI. Broer L, et al. Among authors: spector td. Eur J Hum Genet. 2013 Oct;21(10):1163-8. doi: 10.1038/ejhg.2012.303. Epub 2013 Jan 16. Eur J Hum Genet. 2013. PMID: 23321625 Free PMC article.
Metabolomic markers reveal novel pathways of ageing and early development in human populations.
Menni C, Kastenmüller G, Petersen AK, Bell JT, Psatha M, Tsai PC, Gieger C, Schulz H, Erte I, John S, Brosnan MJ, Wilson SG, Tsaprouni L, Lim EM, Stuckey B, Deloukas P, Mohney R, Suhre K, Spector TD, Valdes AM. Menni C, et al. Among authors: spector td. Int J Epidemiol. 2013 Aug;42(4):1111-9. doi: 10.1093/ije/dyt094. Epub 2013 Jul 8. Int J Epidemiol. 2013. PMID: 23838602 Free PMC article.
Biomarkers for type 2 diabetes and impaired fasting glucose using a nontargeted metabolomics approach.
Menni C, Fauman E, Erte I, Perry JR, Kastenmüller G, Shin SY, Petersen AK, Hyde C, Psatha M, Ward KJ, Yuan W, Milburn M, Palmer CN, Frayling TM, Trimmer J, Bell JT, Gieger C, Mohney RP, Brosnan MJ, Suhre K, Soranzo N, Spector TD. Menni C, et al. Among authors: spector td. Diabetes. 2013 Dec;62(12):4270-6. doi: 10.2337/db13-0570. Epub 2013 Jul 24. Diabetes. 2013. PMID: 23884885 Free PMC article.
Gene expression changes with age in skin, adipose tissue, blood and brain.
Glass D, Viñuela A, Davies MN, Ramasamy A, Parts L, Knowles D, Brown AA, Hedman AK, Small KS, Buil A, Grundberg E, Nica AC, Di Meglio P, Nestle FO, Ryten M; UK Brain Expression consortium; MuTHER consortium; Durbin R, McCarthy MI, Deloukas P, Dermitzakis ET, Weale ME, Bataille V, Spector TD. Glass D, et al. Among authors: spector td. Genome Biol. 2013 Jul 26;14(7):R75. doi: 10.1186/gb-2013-14-7-r75. Genome Biol. 2013. PMID: 23889843 Free PMC article.
1,196 results