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Page 1
Static and turnover kinetic measurement of protein biomarkers involved in triglyceride metabolism including apoB48 and apoA5 by LC/MS/MS.
Pan Y, Zhou H, Mahsut A, Rohm RJ, Berejnaia O, Price O, Chen Y, Castro-Perez J, Lassman ME, McLaren D, Conway J, Jensen KK, Thomas T, Reyes-Soffer G, Ginsberg HN, Gutstein DE, Cleary M, Previs SF, Roddy TP. Pan Y, et al. Among authors: gutstein de. J Lipid Res. 2014 Jun;55(6):1179-87. doi: 10.1194/jlr.D047829. Epub 2014 Apr 2. J Lipid Res. 2014. PMID: 24694356 Free PMC article.
Effects of CETP inhibition with anacetrapib on metabolism of VLDL-TG and plasma apolipoproteins C-II, C-III, and E.
Millar JS, Lassman ME, Thomas T, Ramakrishnan R, Jumes P, Dunbar RL, deGoma EM, Baer AL, Karmally W, Donovan DS, Rafeek H, Wagner JA, Holleran S, Obunike J, Liu Y, Aoujil S, Standiford T, Gutstein DE, Ginsberg HN, Rader DJ, Reyes-Soffer G. Millar JS, et al. Among authors: gutstein de. J Lipid Res. 2017 Jun;58(6):1214-1220. doi: 10.1194/jlr.M074880. Epub 2017 Mar 17. J Lipid Res. 2017. PMID: 28314859 Free PMC article.
Measurement of apo(a) kinetics in human subjects using a microfluidic device with tandem mass spectrometry.
Zhou H, Castro-Perez J, Lassman ME, Thomas T, Li W, McLaughlin T, Dan X, Jumes P, Wagner JA, Gutstein DE, Hubbard BK, Rader DJ, Millar JS, Ginsberg HN, Reyes-Soffer G, Cleary M, Previs SF, Roddy TP. Zhou H, et al. Among authors: gutstein de. Rapid Commun Mass Spectrom. 2013 Jun 30;27(12):1294-302. doi: 10.1002/rcm.6572. Rapid Commun Mass Spectrom. 2013. PMID: 23681806 Free PMC article.
CETP (Cholesteryl Ester Transfer Protein) Inhibition With Anacetrapib Decreases Production of Lipoprotein(a) in Mildly Hypercholesterolemic Subjects.
Thomas T, Zhou H, Karmally W, Ramakrishnan R, Holleran S, Liu Y, Jumes P, Wagner JA, Hubbard B, Previs SF, Roddy T, Johnson-Levonas AO, Gutstein DE, Marcovina SM, Rader DJ, Ginsberg HN, Millar JS, Reyes-Soffer G. Thomas T, et al. Among authors: gutstein de. Arterioscler Thromb Vasc Biol. 2017 Sep;37(9):1770-1775. doi: 10.1161/ATVBAHA.117.309549. Epub 2017 Jul 20. Arterioscler Thromb Vasc Biol. 2017. PMID: 28729361 Free PMC article. Clinical Trial.
Cholesteryl Ester Transfer Protein Inhibition With Anacetrapib Decreases Fractional Clearance Rates of High-Density Lipoprotein Apolipoprotein A-I and Plasma Cholesteryl Ester Transfer Protein.
Reyes-Soffer G, Millar JS, Ngai C, Jumes P, Coromilas E, Asztalos B, Johnson-Levonas AO, Wagner JA, Donovan DS, Karmally W, Ramakrishnan R, Holleran S, Thomas T, Dunbar RL, deGoma EM, Rafeek H, Baer AL, Liu Y, Lassman ME, Gutstein DE, Rader DJ, Ginsberg HN. Reyes-Soffer G, et al. Among authors: gutstein de. Arterioscler Thromb Vasc Biol. 2016 May;36(5):994-1002. doi: 10.1161/ATVBAHA.115.306680. Epub 2016 Mar 10. Arterioscler Thromb Vasc Biol. 2016. PMID: 26966279 Free PMC article. Clinical Trial.
Anacetrapib lowers LDL by increasing ApoB clearance in mildly hypercholesterolemic subjects.
Millar JS, Reyes-Soffer G, Jumes P, Dunbar RL, deGoma EM, Baer AL, Karmally W, Donovan DS, Rafeek H, Pollan L, Tohyama J, Johnson-Levonas AO, Wagner JA, Holleran S, Obunike J, Liu Y, Ramakrishnan R, Lassman ME, Gutstein DE, Ginsberg HN, Rader DJ. Millar JS, et al. Among authors: gutstein de. J Clin Invest. 2015 Jun;125(6):2510-22. doi: 10.1172/JCI80025. Epub 2015 May 11. J Clin Invest. 2015. PMID: 25961461 Free PMC article. Clinical Trial.
Anacetrapib lowers LDL by increasing ApoB clearance in mildly hypercholesterolemic subjects.
Millar JS, Reyes-Soffer G, Jumes P, Dunbar RL, deGoma EM, Baer AL, Karmally W, Donovan DS, Rafeek H, Pollan L, Tohyama J, Johnson-Levonas AO, Wagner JA, Holleran S, Obunike J, Liu Y, Ramakrishnan R, Lassman ME, Gutstein DE, Ginsberg HN, Rader DJ. Millar JS, et al. Among authors: gutstein de. J Clin Invest. 2016 Apr 1;126(4):1603-4. doi: 10.1172/JCI87364. Epub 2016 Apr 1. J Clin Invest. 2016. PMID: 27035815 Free PMC article. No abstract available.
Discovery and Clinical Evaluation of MK-8150, A Novel Nitric Oxide Donor With a Unique Mechanism of Nitric Oxide Release.
Knox CD, de Kam PJ, Azer K, Wong P, Ederveen AG, Shevell D, Morabito C, Meehan AG, Liu W, Reynders T, Denef JF, Mitselos A, Jonathan D, Gutstein DE, Mitra K, Sun SY, Lo MM, Cully D, Ali A. Knox CD, et al. Among authors: de kam pj, gutstein de. J Am Heart Assoc. 2016 Aug 25;5(9):e003493. doi: 10.1161/JAHA.116.003493. J Am Heart Assoc. 2016. PMID: 27561272 Free PMC article.
70 results