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Sirtuins as regulators of metabolism and healthspan.
Houtkooper RH, Pirinen E, Auwerx J. Houtkooper RH, et al. Among authors: auwerx j. Nat Rev Mol Cell Biol. 2012 Mar 7;13(4):225-238. doi: 10.1038/nrm3293. Nat Rev Mol Cell Biol. 2012. PMID: 22395773 Free PMC article. Review.
The NAD(+) precursor nicotinamide riboside enhances oxidative metabolism and protects against high-fat diet-induced obesity.
Cantó C, Houtkooper RH, Pirinen E, Youn DY, Oosterveer MH, Cen Y, Fernandez-Marcos PJ, Yamamoto H, Andreux PA, Cettour-Rose P, Gademann K, Rinsch C, Schoonjans K, Sauve AA, Auwerx J. Cantó C, et al. Among authors: auwerx j. Cell Metab. 2012 Jun 6;15(6):838-47. doi: 10.1016/j.cmet.2012.04.022. Cell Metab. 2012. PMID: 22682224 Free PMC article.
Mitochondrial sirtuins and metabolic homeostasis.
Pirinen E, Lo Sasso G, Auwerx J. Pirinen E, et al. Among authors: auwerx j. Best Pract Res Clin Endocrinol Metab. 2012 Dec;26(6):759-70. doi: 10.1016/j.beem.2012.05.001. Epub 2012 May 31. Best Pract Res Clin Endocrinol Metab. 2012. PMID: 23168278 Free PMC article. Review.
Pharmacological approaches to restore mitochondrial function.
Andreux PA, Houtkooper RH, Auwerx J. Andreux PA, et al. Among authors: auwerx j. Nat Rev Drug Discov. 2013 Jun;12(6):465-83. doi: 10.1038/nrd4023. Epub 2013 May 13. Nat Rev Drug Discov. 2013. PMID: 23666487 Free PMC article. Review.
Pharmacological Inhibition of poly(ADP-ribose) polymerases improves fitness and mitochondrial function in skeletal muscle.
Pirinen E, Cantó C, Jo YS, Morato L, Zhang H, Menzies KJ, Williams EG, Mouchiroud L, Moullan N, Hagberg C, Li W, Timmers S, Imhof R, Verbeek J, Pujol A, van Loon B, Viscomi C, Zeviani M, Schrauwen P, Sauve AA, Schoonjans K, Auwerx J. Pirinen E, et al. Among authors: auwerx j. Cell Metab. 2014 Jun 3;19(6):1034-41. doi: 10.1016/j.cmet.2014.04.002. Epub 2014 May 8. Cell Metab. 2014. PMID: 24814482 Free PMC article.
629 results