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A hybrid qPCR/SNP array approach allows cost efficient assessment of KIR gene copy numbers in large samples.
Pontikos N, Smyth DJ, Schuilenburg H, Howson JM, Walker NM, Burren OS, Guo H, Onengut-Gumuscu S, Chen WM, Concannon P, Rich SS, Jayaraman J, Jiang W, Traherne JA, Trowsdale J, Todd JA, Wallace C. Pontikos N, et al. Among authors: walker nm. BMC Genomics. 2014 Apr 11;15:274. doi: 10.1186/1471-2164-15-274. BMC Genomics. 2014. PMID: 24720548 Free PMC article.
A method for gene-based pathway analysis using genomewide association study summary statistics reveals nine new type 1 diabetes associations.
Evangelou M, Smyth DJ, Fortune MD, Burren OS, Walker NM, Guo H, Onengut-Gumuscu S, Chen WM, Concannon P, Rich SS, Todd JA, Wallace C. Evangelou M, et al. Among authors: walker nm. Genet Epidemiol. 2014 Dec;38(8):661-70. doi: 10.1002/gepi.21853. Epub 2014 Nov 4. Genet Epidemiol. 2014. PMID: 25371288 Free PMC article.
Detection and correction of artefacts in estimation of rare copy number variants and analysis of rare deletions in type 1 diabetes.
Cooper NJ, Shtir CJ, Smyth DJ, Guo H, Swafford AD, Zanda M, Hurles ME, Walker NM, Plagnol V, Cooper JD, Howson JM, Burren OS, Onengut-Gumuscu S, Rich SS, Todd JA. Cooper NJ, et al. Among authors: walker nm. Hum Mol Genet. 2015 Mar 15;24(6):1774-90. doi: 10.1093/hmg/ddu581. Epub 2014 Nov 25. Hum Mol Genet. 2015. PMID: 25424174 Free PMC article.
Dissection of a Complex Disease Susceptibility Region Using a Bayesian Stochastic Search Approach to Fine Mapping.
Wallace C, Cutler AJ, Pontikos N, Pekalski ML, Burren OS, Cooper JD, García AR, Ferreira RC, Guo H, Walker NM, Smyth DJ, Rich SS, Onengut-Gumuscu S, Sawcer SJ, Ban M, Richardson S, Todd JA, Wicker LS. Wallace C, et al. Among authors: walker nm. PLoS Genet. 2015 Jun 24;11(6):e1005272. doi: 10.1371/journal.pgen.1005272. eCollection 2015 Jun. PLoS Genet. 2015. PMID: 26106896 Free PMC article.
Analysis of the vitamin D receptor gene sequence variants in type 1 diabetes.
Nejentsev S, Cooper JD, Godfrey L, Howson JM, Rance H, Nutland S, Walker NM, Guja C, Ionescu-Tirgovişte C, Savage DA, Undlien DE, Rønningen KS, Tuomilehto-Wolf E, Tuomilehto J, Gillespie KM, Ring SM, Strachan DP, Widmer B, Dunger D, Todd JA. Nejentsev S, et al. Among authors: walker nm. Diabetes. 2004 Oct;53(10):2709-12. doi: 10.2337/diabetes.53.10.2709. Diabetes. 2004. PMID: 15448105
Development of an integrated genome informatics, data management and workflow infrastructure: a toolbox for the study of complex disease genetics.
Burren OS, Healy BC, Lam AC, Schuilenburg H, Dolman GE, Everett VH, Laneri D, Nutland S, Rance HE, Payne F, Smyth D, Lowe C, Barratt BJ, Twells RC, Rainbow DB, Wicker LS, Todd JA, Walker NM, Smink LJ. Burren OS, et al. Among authors: walker nm. Hum Genomics. 2004 Jan;1(2):98-109. doi: 10.1186/1479-7364-1-2-98. Hum Genomics. 2004. PMID: 15601538 Free PMC article.
T1DBase, a community web-based resource for type 1 diabetes research.
Smink LJ, Helton EM, Healy BC, Cavnor CC, Lam AC, Flamez D, Burren OS, Wang Y, Dolman GE, Burdick DB, Everett VH, Glusman G, Laneri D, Rowen L, Schuilenburg H, Walker NM, Mychaleckyj J, Wicker LS, Eizirik DL, Todd JA, Goodman N. Smink LJ, et al. Among authors: walker nm. Nucleic Acids Res. 2005 Jan 1;33(Database issue):D544-9. doi: 10.1093/nar/gki095. Nucleic Acids Res. 2005. PMID: 15608258 Free PMC article.
165 results