Dobson CM - Search Results

1

Oligomer-targeting with a conformational antibody fragment promotes toxicity in Aβ-expressing flies.

Wacker J, Rönicke R, Westermann M, Wulff M, Reymann KG, Dobson CM, Horn U, Crowther DC, Luheshi LM, Fändrich M. Wacker J, et al. Among authors: dobson cm. Acta Neuropathol Commun. 2014 Apr 11;2:43. doi: 10.1186/2051-5960-2-43. Acta Neuropathol Commun. 2014. PMID: 24725347 Free PMC article.

2

Sequestration of the Abeta peptide prevents toxicity and promotes degradation in vivo.

Luheshi LM, Hoyer W, de Barros TP, van Dijk Härd I, Brorsson AC, Macao B, Persson C, Crowther DC, Lomas DA, Ståhl S, Dobson CM, Härd T. Luheshi LM, et al. Among authors: dobson cm. PLoS Biol. 2010 Mar 16;8(3):e1000334. doi: 10.1371/journal.pbio.1000334. PLoS Biol. 2010. PMID: 20305716 Free PMC article.

3

Systematic in vivo analysis of the intrinsic determinants of amyloid Beta pathogenicity.

Luheshi LM, Tartaglia GG, Brorsson AC, Pawar AP, Watson IE, Chiti F, Vendruscolo M, Lomas DA, Dobson CM, Crowther DC. Luheshi LM, et al. Among authors: dobson cm. PLoS Biol. 2007 Oct 30;5(11):e290. doi: 10.1371/journal.pbio.0050290. PLoS Biol. 2007. PMID: 17973577 Free PMC article.

4

Protein misfolding and disease: from the test tube to the organism.

Luheshi LM, Crowther DC, Dobson CM. Luheshi LM, et al. Among authors: dobson cm. Curr Opin Chem Biol. 2008 Feb;12(1):25-31. doi: 10.1016/j.cbpa.2008.02.011. Epub 2008 Mar 18. Curr Opin Chem Biol. 2008. PMID: 18295611 Review.

5

Bridging the gap: from protein misfolding to protein misfolding diseases.

Luheshi LM, Dobson CM. Luheshi LM, et al. Among authors: dobson cm. FEBS Lett. 2009 Aug 20;583(16):2581-6. doi: 10.1016/j.febslet.2009.06.030. Epub 2009 Jun 21. FEBS Lett. 2009. PMID: 19545568 Free article. Review.

6

ANS binding reveals common features of cytotoxic amyloid species.

Bolognesi B, Kumita JR, Barros TP, Esbjorner EK, Luheshi LM, Crowther DC, Wilson MR, Dobson CM, Favrin G, Yerbury JJ. Bolognesi B, et al. Among authors: dobson cm. ACS Chem Biol. 2010 Aug 20;5(8):735-40. doi: 10.1021/cb1001203. ACS Chem Biol. 2010. PMID: 20550130

7

Expression in drosophila of tandem amyloid β peptides provides insights into links between aggregation and neurotoxicity.

Speretta E, Jahn TR, Tartaglia GG, Favrin G, Barros TP, Imarisio S, Lomas DA, Luheshi LM, Crowther DC, Dobson CM. Speretta E, et al. Among authors: dobson cm. J Biol Chem. 2012 Jun 8;287(24):20748-54. doi: 10.1074/jbc.M112.350124. Epub 2012 Mar 29. J Biol Chem. 2012. PMID: 22461632 Free PMC article.

8

Clusterin protects neurons against intracellular proteotoxicity.

Gregory JM, Whiten DR, Brown RA, Barros TP, Kumita JR, Yerbury JJ, Satapathy S, McDade K, Smith C, Luheshi LM, Dobson CM, Wilson MR. Gregory JM, et al. Among authors: dobson cm. Acta Neuropathol Commun. 2017 Nov 7;5(1):81. doi: 10.1186/s40478-017-0481-1. Acta Neuropathol Commun. 2017. PMID: 29115989 Free PMC article.

9

Methods and models in neurodegenerative and systemic protein aggregation diseases.

Brorsson AC, Kumita JR, MacLeod I, Bolognesi B, Speretta E, Luheshi LM, Knowles TP, Dobson CM, Crowther DC. Brorsson AC, et al. Among authors: dobson cm. Front Biosci (Landmark Ed). 2010 Jan 1;15(1):373-96. doi: 10.2741/3626. Front Biosci (Landmark Ed). 2010. PMID: 20036826 Free article. Review.

10

Intrinsic determinants of neurotoxic aggregate formation by the amyloid beta peptide.

Brorsson AC, Bolognesi B, Tartaglia GG, Shammas SL, Favrin G, Watson I, Lomas DA, Chiti F, Vendruscolo M, Dobson CM, Crowther DC, Luheshi LM. Brorsson AC, et al. Among authors: dobson cm. Biophys J. 2010 Apr 21;98(8):1677-84. doi: 10.1016/j.bpj.2009.12.4320. Biophys J. 2010. PMID: 20409489 Free PMC article.

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