Liu H - Search Results

1

Syk inhibitors with high potency in presence of blood.

Thoma G, Blanz J, Bühlmayer P, Drückes P, Kittelmann M, Smith AB, van Eis M, Vangrevelinghe E, Zerwes HG, Che JJ, He X, Jin Y, Lee CC, Michellys PY, Uno T, Liu H. Thoma G, et al. Among authors: liu h. Bioorg Med Chem Lett. 2014 May 15;24(10):2278-82. doi: 10.1016/j.bmcl.2014.03.075. Epub 2014 Apr 3. Bioorg Med Chem Lett. 2014. PMID: 24726806

2

Design and synthesis of arylaminoethyl amides as noncovalent inhibitors of cathepsin S. Part 1.

Liu H, Tully DC, Epple R, Bursulaya B, Li J, Harris JL, Williams JA, Russo R, Tumanut C, Roberts MJ, Alper PB, He Y, Karanewsky DS. Liu H, et al. Bioorg Med Chem Lett. 2005 Nov 15;15(22):4979-84. doi: 10.1016/j.bmcl.2005.08.017. Epub 2005 Sep 23. Bioorg Med Chem Lett. 2005. PMID: 16183279

3

Arylaminoethyl amides as noncovalent inhibitors of cathepsin S. Part 2: Optimization of P1 and N-aryl.

Alper PB, Liu H, Chatterjee AK, Nguyen KT, Tully DC, Tumanut C, Li J, Harris JL, Tuntland T, Chang J, Gordon P, Hollenbeck T, Karanewsky DS. Alper PB, et al. Among authors: liu h. Bioorg Med Chem Lett. 2006 Mar 15;16(6):1486-90. doi: 10.1016/j.bmcl.2005.12.056. Epub 2006 Jan 18. Bioorg Med Chem Lett. 2006. PMID: 16412634

4

Synthesis and evaluation of arylaminoethyl amides as noncovalent inhibitors of cathepsin S. Part 3: heterocyclic P3.

Tully DC, Liu H, Alper PB, Chatterjee AK, Epple R, Roberts MJ, Williams JA, Nguyen KT, Woodmansee DH, Tumanut C, Li J, Spraggon G, Chang J, Tuntland T, Harris JL, Karanewsky DS. Tully DC, et al. Among authors: liu h. Bioorg Med Chem Lett. 2006 Apr 1;16(7):1975-80. doi: 10.1016/j.bmcl.2005.12.095. Epub 2006 Jan 30. Bioorg Med Chem Lett. 2006. PMID: 16446091

5

Synthesis and SAR of arylaminoethyl amides as noncovalent inhibitors of cathepsin S: P3 cyclic ethers.

Tully DC, Liu H, Chatterjee AK, Alper PB, Epple R, Williams JA, Roberts MJ, Woodmansee DH, Masick BT, Tumanut C, Li J, Spraggon G, Hornsby M, Chang J, Tuntland T, Hollenbeck T, Gordon P, Harris JL, Karanewsky DS. Tully DC, et al. Among authors: liu h. Bioorg Med Chem Lett. 2006 Oct 1;16(19):5112-7. doi: 10.1016/j.bmcl.2006.07.033. Epub 2006 Jul 28. Bioorg Med Chem Lett. 2006. PMID: 16876402

6

Arylaminoethyl carbamates as a novel series of potent and selective cathepsin S inhibitors.

Tully DC, Liu H, Chatterjee AK, Alper PB, Williams JA, Roberts MJ, Mutnick D, Woodmansee DH, Hollenbeck T, Gordon P, Chang J, Tuntland T, Tumanut C, Li J, Harris JL, Karanewsky DS. Tully DC, et al. Among authors: liu h. Bioorg Med Chem Lett. 2006 Oct 1;16(19):5107-11. doi: 10.1016/j.bmcl.2006.07.032. Epub 2006 Jul 28. Bioorg Med Chem Lett. 2006. PMID: 16876407

7

Novel 5-(benzyloxy)pyridin-2(1H)-one derivatives as potent c-Met inhibitors.

Zhang D, Ai J, Liang Z, Zhu W, Peng X, Chen X, Ji Y, Jiang H, Luo C, Geng M, Liu H. Zhang D, et al. Among authors: liu h. Bioorg Med Chem Lett. 2013 Apr 15;23(8):2408-13. doi: 10.1016/j.bmcl.2013.02.037. Epub 2013 Feb 14. Bioorg Med Chem Lett. 2013. PMID: 23474386

8

Identification and synthesis of N-(thiophen-2-yl) benzamide derivatives as BRAF(V600E) inhibitors.

Xie Y, Chen X, Qin J, Kong X, Ye F, Jiang Y, Liu H, Jiang H, Marmorstein R, Luo C. Xie Y, et al. Among authors: liu h. Bioorg Med Chem Lett. 2013 Apr 15;23(8):2306-12. doi: 10.1016/j.bmcl.2013.02.072. Epub 2013 Feb 26. Bioorg Med Chem Lett. 2013. PMID: 23489628 Free PMC article.

9

(R)-3-amino-1-((3aS,7aS)-octahydro-1H-indol-1-yl)-4-(2,4,5-trifluorophenyl)butan-1-one derivatives as potent inhibitors of dipeptidyl peptidase-4: design, synthesis, biological evaluation, and molecular modeling.

Wang S, Su M, Wang J, Li Z, Zhang L, Ji X, Li J, Li J, Liu H. Wang S, et al. Among authors: liu h. Bioorg Med Chem. 2014 Dec 1;22(23):6684-6693. doi: 10.1016/j.bmc.2014.09.051. Epub 2014 Oct 23. Bioorg Med Chem. 2014. PMID: 25457126

10

Design, synthesis and biological evaluation of isoquinoline-based derivatives as novel histone deacetylase inhibitors.

Yang W, Li L, Wang Y, Wu X, Li T, Yang N, Su M, Sheng L, Zheng M, Zang Y, Li J, Liu H. Yang W, et al. Among authors: liu h. Bioorg Med Chem. 2015 Sep 1;23(17):5881-90. doi: 10.1016/j.bmc.2015.06.071. Epub 2015 Jul 4. Bioorg Med Chem. 2015. PMID: 26211462

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