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An integrated epigenetic and transcriptomic analysis reveals distinct tissue-specific patterns of DNA methylation associated with atopic dermatitis.
Rodríguez E, Baurecht H, Wahn AF, Kretschmer A, Hotze M, Zeilinger S, Klopp N, Illig T, Schramm K, Prokisch H, Kühnel B, Gieger C, Harder J, Cifuentes L, Novak N, Weidinger S. Rodríguez E, et al. Among authors: schramm k. J Invest Dermatol. 2014 Jul;134(7):1873-1883. doi: 10.1038/jid.2014.87. Epub 2014 Feb 13. J Invest Dermatol. 2014. PMID: 24739813 Free article.
Association between DNA Methylation in Whole Blood and Measures of Glucose Metabolism: KORA F4 Study.
Kriebel J, Herder C, Rathmann W, Wahl S, Kunze S, Molnos S, Volkova N, Schramm K, Carstensen-Kirberg M, Waldenberger M, Gieger C, Peters A, Illig T, Prokisch H, Roden M, Grallert H. Kriebel J, et al. Among authors: schramm k. PLoS One. 2016 Mar 28;11(3):e0152314. doi: 10.1371/journal.pone.0152314. eCollection 2016. PLoS One. 2016. PMID: 27019061 Free PMC article.
A common atopy-associated variant in the Th2 cytokine locus control region impacts transcriptional regulation and alters SMAD3 and SP1 binding.
Kretschmer A, Möller G, Lee H, Laumen H, von Toerne C, Schramm K, Prokisch H, Eyerich S, Wahl S, Baurecht H, Franke A, Claussnitzer M, Eyerich K, Teumer A, Milani L, Klopp N, Hauck SM, Illig T, Peters A, Waldenberger M, Adamski J, Reischl E, Weidinger S. Kretschmer A, et al. Among authors: schramm k. Allergy. 2014 May;69(5):632-42. doi: 10.1111/all.12394. Epub 2014 Mar 25. Allergy. 2014. PMID: 24661001
Characterization of whole-genome autosomal differences of DNA methylation between men and women.
Singmann P, Shem-Tov D, Wahl S, Grallert H, Fiorito G, Shin SY, Schramm K, Wolf P, Kunze S, Baran Y, Guarrera S, Vineis P, Krogh V, Panico S, Tumino R, Kretschmer A, Gieger C, Peters A, Prokisch H, Relton CL, Matullo G, Illig T, Waldenberger M, Halperin E. Singmann P, et al. Among authors: schramm k. Epigenetics Chromatin. 2015 Oct 19;8:43. doi: 10.1186/s13072-015-0035-3. eCollection 2015. Epigenetics Chromatin. 2015. PMID: 26500701 Free PMC article.
Epigenome-wide association study of whole blood gene expression in Framingham Heart Study participants provides molecular insight into the potential role of CHRNA5 in cigarette smoking-related lung diseases.
Yao C, Joehanes R, Wilson R, Tanaka T, Ferrucci L, Kretschmer A, Prokisch H, Schramm K, Gieger C, Peters A, Waldenberger M, Marzi C, Herder C, Levy D. Yao C, et al. Among authors: schramm k. Clin Epigenetics. 2021 Mar 22;13(1):60. doi: 10.1186/s13148-021-01041-5. Clin Epigenetics. 2021. PMID: 33752734 Free PMC article.
DNA methylation of lipid-related genes affects blood lipid levels.
Pfeiffer L, Wahl S, Pilling LC, Reischl E, Sandling JK, Kunze S, Holdt LM, Kretschmer A, Schramm K, Adamski J, Klopp N, Illig T, Hedman ÅK, Roden M, Hernandez DG, Singleton AB, Thasler WE, Grallert H, Gieger C, Herder C, Teupser D, Meisinger C, Spector TD, Kronenberg F, Prokisch H, Melzer D, Peters A, Deloukas P, Ferrucci L, Waldenberger M. Pfeiffer L, et al. Among authors: schramm k. Circ Cardiovasc Genet. 2015 Apr;8(2):334-42. doi: 10.1161/CIRCGENETICS.114.000804. Epub 2015 Jan 12. Circ Cardiovasc Genet. 2015. PMID: 25583993 Free PMC article. Clinical Trial.
Extensive alterations of the whole-blood transcriptome are associated with body mass index: results of an mRNA profiling study involving two large population-based cohorts.
Homuth G, Wahl S, Müller C, Schurmann C, Mäder U, Blankenberg S, Carstensen M, Dörr M, Endlich K, Englbrecht C, Felix SB, Gieger C, Grallert H, Herder C, Illig T, Kruppa J, Marzi CS, Mayerle J, Meitinger T, Metspalu A, Nauck M, Peters A, Rathmann W, Reinmaa E, Rettig R, Roden M, Schillert A, Schramm K, Steil L, Strauch K, Teumer A, Völzke H, Wallaschofski H, Wild PS, Ziegler A, Völker U, Prokisch H, Zeller T. Homuth G, et al. Among authors: schramm k. BMC Med Genomics. 2015 Oct 15;8:65. doi: 10.1186/s12920-015-0141-x. BMC Med Genomics. 2015. PMID: 26470795 Free PMC article.
The transcriptional landscape of age in human peripheral blood.
Peters MJ, Joehanes R, Pilling LC, Schurmann C, Conneely KN, Powell J, Reinmaa E, Sutphin GL, Zhernakova A, Schramm K, Wilson YA, Kobes S, Tukiainen T; NABEC/UKBEC Consortium; Ramos YF, Göring HH, Fornage M, Liu Y, Gharib SA, Stranger BE, De Jager PL, Aviv A, Levy D, Murabito JM, Munson PJ, Huan T, Hofman A, Uitterlinden AG, Rivadeneira F, van Rooij J, Stolk L, Broer L, Verbiest MM, Jhamai M, Arp P, Metspalu A, Tserel L, Milani L, Samani NJ, Peterson P, Kasela S, Codd V, Peters A, Ward-Caviness CK, Herder C, Waldenberger M, Roden M, Singmann P, Zeilinger S, Illig T, Homuth G, Grabe HJ, Völzke H, Steil L, Kocher T, Murray A, Melzer D, Yaghootkar H, Bandinelli S, Moses EK, Kent JW, Curran JE, Johnson MP, Williams-Blangero S, Westra HJ, McRae AF, Smith JA, Kardia SL, Hovatta I, Perola M, Ripatti S, Salomaa V, Henders AK, Martin NG, Smith AK, Mehta D, Binder EB, Nylocks KM, Kennedy EM, Klengel T, Ding J, Suchy-Dicey AM, Enquobahrie DA, Brody J, Rotter JI, Chen YD, Houwing-Duistermaat J, Kloppenburg M, Slagboom PE, Helmer Q, den Hollander W, Bean S, Raj T, Bakhshi N, Wang QP, Oyston LJ, Psaty BM, Tracy RP, Montgomery GW, Turner ST, Blangero J, Meulenbelt I, Ressler KJ, Yang J, F… See abstract for full author list ➔ Peters MJ, et al. Among authors: schramm k. Nat Commun. 2015 Oct 22;6:8570. doi: 10.1038/ncomms9570. Nat Commun. 2015. PMID: 26490707 Free PMC article.
Epigenome-wide association study of body mass index, and the adverse outcomes of adiposity.
Wahl S, Drong A, Lehne B, Loh M, Scott WR, Kunze S, Tsai PC, Ried JS, Zhang W, Yang Y, Tan S, Fiorito G, Franke L, Guarrera S, Kasela S, Kriebel J, Richmond RC, Adamo M, Afzal U, Ala-Korpela M, Albetti B, Ammerpohl O, Apperley JF, Beekman M, Bertazzi PA, Black SL, Blancher C, Bonder MJ, Brosch M, Carstensen-Kirberg M, de Craen AJ, de Lusignan S, Dehghan A, Elkalaawy M, Fischer K, Franco OH, Gaunt TR, Hampe J, Hashemi M, Isaacs A, Jenkinson A, Jha S, Kato N, Krogh V, Laffan M, Meisinger C, Meitinger T, Mok ZY, Motta V, Ng HK, Nikolakopoulou Z, Nteliopoulos G, Panico S, Pervjakova N, Prokisch H, Rathmann W, Roden M, Rota F, Rozario MA, Sandling JK, Schafmayer C, Schramm K, Siebert R, Slagboom PE, Soininen P, Stolk L, Strauch K, Tai ES, Tarantini L, Thorand B, Tigchelaar EF, Tumino R, Uitterlinden AG, van Duijn C, van Meurs JB, Vineis P, Wickremasinghe AR, Wijmenga C, Yang TP, Yuan W, Zhernakova A, Batterham RL, Smith GD, Deloukas P, Heijmans BT, Herder C, Hofman A, Lindgren CM, Milani L, van der Harst P, Peters A, Illig T, Relton CL, Waldenberger M, Järvelin MR, Bollati V, Soong R, Spector TD, Scott J, McCarthy MI, Elliott P, Bell JT, Matullo G, Gieger C, Kooner JS, Grallert … See abstract for full author list ➔ Wahl S, et al. Among authors: schramm k. Nature. 2017 Jan 5;541(7635):81-86. doi: 10.1038/nature20784. Epub 2016 Dec 21. Nature. 2017. PMID: 28002404 Free PMC article.
Mapping the genetic architecture of gene regulation in whole blood.
Schramm K, Marzi C, Schurmann C, Carstensen M, Reinmaa E, Biffar R, Eckstein G, Gieger C, Grabe HJ, Homuth G, Kastenmüller G, Mägi R, Metspalu A, Mihailov E, Peters A, Petersmann A, Roden M, Strauch K, Suhre K, Teumer A, Völker U, Völzke H, Wang-Sattler R, Waldenberger M, Meitinger T, Illig T, Herder C, Grallert H, Prokisch H. Schramm K, et al. PLoS One. 2014 Apr 16;9(4):e93844. doi: 10.1371/journal.pone.0093844. eCollection 2014. PLoS One. 2014. PMID: 24740359 Free PMC article.
438 results