Shaw R - Search Results

1

Leptin-mediated increases in catecholamine signaling reduce adipose tissue inflammation via activation of macrophage HDAC4.

Luan B, Goodarzi MO, Phillips NG, Guo X, Chen YD, Yao J, Allison M, Rotter JI, Shaw R, Montminy M. Luan B, et al. Among authors: shaw r. Cell Metab. 2014 Jun 3;19(6):1058-65. doi: 10.1016/j.cmet.2014.03.024. Epub 2014 Apr 24. Cell Metab. 2014. PMID: 24768298 Free PMC article.

2

The kinase LKB1 mediates glucose homeostasis in liver and therapeutic effects of metformin.

Shaw RJ, Lamia KA, Vasquez D, Koo SH, Bardeesy N, Depinho RA, Montminy M, Cantley LC. Shaw RJ, et al. Science. 2005 Dec 9;310(5754):1642-6. doi: 10.1126/science.1120781. Epub 2005 Nov 24. Science. 2005. PMID: 16308421 Free PMC article.

3

Raptor swoops in on metabolism.

Shaw RJ. Shaw RJ. Cell Metab. 2008 Nov;8(5):343-4. doi: 10.1016/j.cmet.2008.10.007. Cell Metab. 2008. PMID: 19046565 Free article.

4

Lifespan extension induced by AMPK and calcineurin is mediated by CRTC-1 and CREB.

Mair W, Morantte I, Rodrigues AP, Manning G, Montminy M, Shaw RJ, Dillin A. Mair W, et al. Nature. 2011 Feb 17;470(7334):404-8. doi: 10.1038/nature09706. Nature. 2011. PMID: 21331044 Free PMC article.

5

AMPK phosphorylates and inhibits SREBP activity to attenuate hepatic steatosis and atherosclerosis in diet-induced insulin-resistant mice.

Li Y, Xu S, Mihaylova MM, Zheng B, Hou X, Jiang B, Park O, Luo Z, Lefai E, Shyy JY, Gao B, Wierzbicki M, Verbeuren TJ, Shaw RJ, Cohen RA, Zang M. Li Y, et al. Cell Metab. 2011 Apr 6;13(4):376-388. doi: 10.1016/j.cmet.2011.03.009. Cell Metab. 2011. PMID: 21459323 Free PMC article.

6

A hormone-dependent module regulating energy balance.

Wang B, Moya N, Niessen S, Hoover H, Mihaylova MM, Shaw RJ, Yates JR 3rd, Fischer WH, Thomas JB, Montminy M. Wang B, et al. Among authors: shaw rj. Cell. 2011 May 13;145(4):596-606. doi: 10.1016/j.cell.2011.04.013. Cell. 2011. PMID: 21565616 Free PMC article.

7

Class IIa histone deacetylases are hormone-activated regulators of FOXO and mammalian glucose homeostasis.

Mihaylova MM, Vasquez DS, Ravnskjaer K, Denechaud PD, Yu RT, Alvarez JG, Downes M, Evans RM, Montminy M, Shaw RJ. Mihaylova MM, et al. Cell. 2011 May 13;145(4):607-21. doi: 10.1016/j.cell.2011.03.043. Cell. 2011. PMID: 21565617 Free PMC article.

8

mTOR complex 2 controls glycolytic metabolism in glioblastoma through FoxO acetylation and upregulation of c-Myc.

Masui K, Tanaka K, Akhavan D, Babic I, Gini B, Matsutani T, Iwanami A, Liu F, Villa GR, Gu Y, Campos C, Zhu S, Yang H, Yong WH, Cloughesy TF, Mellinghoff IK, Cavenee WK, Shaw RJ, Mischel PS. Masui K, et al. Among authors: shaw rj. Cell Metab. 2013 Nov 5;18(5):726-39. doi: 10.1016/j.cmet.2013.09.013. Epub 2013 Oct 17. Cell Metab. 2013. PMID: 24140020 Free PMC article.

9

Transcriptional coregulators: fine-tuning metabolism.

Mouchiroud L, Eichner LJ, Shaw RJ, Auwerx J. Mouchiroud L, et al. Cell Metab. 2014 Jul 1;20(1):26-40. doi: 10.1016/j.cmet.2014.03.027. Epub 2014 May 1. Cell Metab. 2014. PMID: 24794975 Free PMC article. Review.

10

Identification of AMPK Phosphorylation Sites Reveals a Network of Proteins Involved in Cell Invasion and Facilitates Large-Scale Substrate Prediction.

Schaffer BE, Levin RS, Hertz NT, Maures TJ, Schoof ML, Hollstein PE, Benayoun BA, Banko MR, Shaw RJ, Shokat KM, Brunet A. Schaffer BE, et al. Among authors: shaw rj. Cell Metab. 2015 Nov 3;22(5):907-21. doi: 10.1016/j.cmet.2015.09.009. Epub 2015 Oct 8. Cell Metab. 2015. PMID: 26456332 Free PMC article.

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