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FGFR1 mRNA and protein expression, not gene copy number, predict FGFR TKI sensitivity across all lung cancer histologies.
Wynes MW, Hinz TK, Gao D, Martini M, Marek LA, Ware KE, Edwards MG, Böhm D, Perner S, Helfrich BA, Dziadziuszko R, Jassem J, Wojtylak S, Sejda A, Gozgit JM, Bunn PA Jr, Camidge DR, Tan AC, Hirsch FR, Heasley LE. Wynes MW, et al. Among authors: heasley le. Clin Cancer Res. 2014 Jun 15;20(12):3299-309. doi: 10.1158/1078-0432.CCR-13-3060. Epub 2014 Apr 25. Clin Cancer Res. 2014. PMID: 24771645 Free PMC article.
Restoration of Wnt-7a expression reverses non-small cell lung cancer cellular transformation through frizzled-9-mediated growth inhibition and promotion of cell differentiation.
Winn RA, Marek L, Han SY, Rodriguez K, Rodriguez N, Hammond M, Van Scoyk M, Acosta H, Mirus J, Barry N, Bren-Mattison Y, Van Raay TJ, Nemenoff RA, Heasley LE. Winn RA, et al. Among authors: heasley le. J Biol Chem. 2005 May 20;280(20):19625-34. doi: 10.1074/jbc.M409392200. Epub 2005 Feb 10. J Biol Chem. 2005. PMID: 15705594 Free article.
Inhibited neurogenesis in JNK1-deficient embryonic stem cells.
Amura CR, Marek L, Winn RA, Heasley LE. Amura CR, et al. Among authors: heasley le. Mol Cell Biol. 2005 Dec;25(24):10791-802. doi: 10.1128/MCB.25.24.10791-10802.2005. Mol Cell Biol. 2005. PMID: 16314504 Free PMC article.
139 results