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Polarization of the effects of autoimmune and neurodegenerative risk alleles in leukocytes.
Raj T, Rothamel K, Mostafavi S, Ye C, Lee MN, Replogle JM, Feng T, Lee M, Asinovski N, Frohlich I, Imboywa S, Von Korff A, Okada Y, Patsopoulos NA, Davis S, McCabe C, Paik HI, Srivastava GP, Raychaudhuri S, Hafler DA, Koller D, Regev A, Hacohen N, Mathis D, Benoist C, Stranger BE, De Jager PL. Raj T, et al. Among authors: srivastava gp. Science. 2014 May 2;344(6183):519-23. doi: 10.1126/science.1249547. Science. 2014. PMID: 24786080 Free PMC article.
Rheumatoid arthritis-associated RBPJ polymorphism alters memory CD4+ T cells.
Orent W, Mchenry AR, Rao DA, White C, Klein HU, Bassil R, Srivastava G, Replogle JM, Raj T, Frangieh M, Cimpean M, Cuerdon N, Chibnik L, Khoury SJ, Karlson EW, Brenner MB, De Jager P, Bradshaw EM, Elyaman W. Orent W, et al. Hum Mol Genet. 2016 Jan 15;25(2):404-17. doi: 10.1093/hmg/ddv474. Epub 2015 Nov 24. Hum Mol Genet. 2016. PMID: 26604133 Free PMC article.
Epigenomics of Alzheimer's disease.
Bennett DA, Yu L, Yang J, Srivastava GP, Aubin C, De Jager PL. Bennett DA, et al. Among authors: srivastava gp. Transl Res. 2015 Jan;165(1):200-20. doi: 10.1016/j.trsl.2014.05.006. Epub 2014 May 16. Transl Res. 2015. PMID: 24905038 Free PMC article. Review.
Alzheimer's disease: early alterations in brain DNA methylation at ANK1, BIN1, RHBDF2 and other loci.
De Jager PL, Srivastava G, Lunnon K, Burgess J, Schalkwyk LC, Yu L, Eaton ML, Keenan BT, Ernst J, McCabe C, Tang A, Raj T, Replogle J, Brodeur W, Gabriel S, Chai HS, Younkin C, Younkin SG, Zou F, Szyf M, Epstein CB, Schneider JA, Bernstein BE, Meissner A, Ertekin-Taner N, Chibnik LB, Kellis M, Mill J, Bennett DA. De Jager PL, et al. Nat Neurosci. 2014 Sep;17(9):1156-63. doi: 10.1038/nn.3786. Epub 2014 Aug 17. Nat Neurosci. 2014. PMID: 25129075 Free PMC article.
The Role of MAPT Haplotype H2 and Isoform 1N/4R in Parkinsonism of Older Adults.
Valenca GT, Srivastava GP, Oliveira-Filho J, White CC, Yu L, Schneider JA, Buchman AS, Shulman JM, Bennett DA, De Jager PL. Valenca GT, et al. Among authors: srivastava gp. PLoS One. 2016 Jul 26;11(7):e0157452. doi: 10.1371/journal.pone.0157452. eCollection 2016. PLoS One. 2016. PMID: 27458716 Free PMC article.
A 17q12 allele is associated with altered NK cell subsets and function.
Xia Z, Liu Q, Berger CT, Keenan BT, Kaliszewska A, Cheney PC, Srivastava GP, Castillo IW, De Jager PL, Alter G. Xia Z, et al. Among authors: srivastava gp. J Immunol. 2012 Apr 1;188(7):3315-22. doi: 10.4049/jimmunol.1102775. Epub 2012 Feb 15. J Immunol. 2012. PMID: 22345646 Free PMC article.
Methylomic profiling implicates cortical deregulation of ANK1 in Alzheimer's disease.
Lunnon K, Smith R, Hannon E, De Jager PL, Srivastava G, Volta M, Troakes C, Al-Sarraj S, Burrage J, Macdonald R, Condliffe D, Harries LW, Katsel P, Haroutunian V, Kaminsky Z, Joachim C, Powell J, Lovestone S, Bennett DA, Schalkwyk LC, Mill J. Lunnon K, et al. Nat Neurosci. 2014 Sep;17(9):1164-70. doi: 10.1038/nn.3782. Epub 2014 Aug 17. Nat Neurosci. 2014. PMID: 25129077 Free PMC article.
89 results