Young JD - Search Results

1

Synthesis of purine and 7-deazapurine nucleoside analogues of 6-N-(4-Nitrobenzyl)adenosine; inhibition of nucleoside transport and proliferation of cancer cells.

Rayala R, Theard P, Ortiz H, Yao S, Young JD, Balzarini J, Robins MJ, Wnuk SF. Rayala R, et al. Among authors: young jd. ChemMedChem. 2014 Sep;9(9):2186-92. doi: 10.1002/cmdc.201402047. Epub 2014 Apr 30. ChemMedChem. 2014. PMID: 24788480 Free PMC article.

2

Improved syntheses of 5'-S-(2-aminoethyl)-6-N-(4-nitrobenzyl)-5'-thioadenosine (SAENTA), analogues, and fluorescent probe conjugates: analysis of cell-surface human equilibrative nucleoside transporter 1 (hENT1) levels for prediction of the antitumor efficacy of gemcitabine.

Robins MJ, Peng Y, Damaraju VL, Mowles D, Barron G, Tackaberry T, Young JD, Cass CE. Robins MJ, et al. Among authors: young jd. J Med Chem. 2010 Aug 26;53(16):6040-53. doi: 10.1021/jm100432w. J Med Chem. 2010. PMID: 20718495

3

Inward- and outward-facing homology modeling of human concentrative nucleoside transporter 3 (hCNT3) predicts an elevator-type transport mechanism.

Yao SYM, Young JD. Yao SYM, et al. Among authors: young jd. Channels (Austin). 2018;12(1):291-298. doi: 10.1080/19336950.2018.1506665. Channels (Austin). 2018. PMID: 30096006 Free PMC article.

4

The equilibrative nucleoside transporter family, SLC29.

Baldwin SA, Beal PR, Yao SY, King AE, Cass CE, Young JD. Baldwin SA, et al. Among authors: young jd. Pflugers Arch. 2004 Feb;447(5):735-43. doi: 10.1007/s00424-003-1103-2. Epub 2003 Jun 28. Pflugers Arch. 2004. PMID: 12838422 Review.

5

Studies of nucleoside transporters using novel autofluorescent nucleoside probes.

Zhang J, Sun X, Smith KM, Visser F, Carpenter P, Barron G, Peng Y, Robins MJ, Baldwin SA, Young JD, Cass CE. Zhang J, et al. Among authors: young jd. Biochemistry. 2006 Jan 31;45(4):1087-98. doi: 10.1021/bi0520535. Biochemistry. 2006. PMID: 16430205

6

Interaction of fused-pyrimidine nucleoside analogs with human concentrative nucleoside transporters: High-affinity inhibitors of human concentrative nucleoside transporter 1.

Damaraju VL, Smith KM, Mowles D, Nowak I, Karpinski E, Young JD, Robins MJ, Cass CE. Damaraju VL, et al. Among authors: young jd. Biochem Pharmacol. 2011 Jan 1;81(1):82-90. doi: 10.1016/j.bcp.2010.09.009. Epub 2010 Sep 18. Biochem Pharmacol. 2011. PMID: 20854794

7

Nucleobase transport by human equilibrative nucleoside transporter 1 (hENT1).

Yao SY, Ng AM, Cass CE, Baldwin SA, Young JD. Yao SY, et al. Among authors: young jd. J Biol Chem. 2011 Sep 16;286(37):32552-62. doi: 10.1074/jbc.M111.236117. Epub 2011 Jul 27. J Biol Chem. 2011. PMID: 21795683 Free PMC article.

8

Role of cysteine 416 in N-ethylmaleimide sensitivity of human equilibrative nucleoside transporter 1 (hENT1).

Yao SYM, Ng AML, Cass CE, Young JD. Yao SYM, et al. Among authors: young jd. Biochem J. 2018 Oct 31;475(20):3293-3309. doi: 10.1042/BCJ20180543. Biochem J. 2018. PMID: 30254099

9

Cloning of a human nucleoside transporter implicated in the cellular uptake of adenosine and chemotherapeutic drugs.

Griffiths M, Beaumont N, Yao SY, Sundaram M, Boumah CE, Davies A, Kwong FY, Coe I, Cass CE, Young JD, Baldwin SA. Griffiths M, et al. Among authors: young jd. Nat Med. 1997 Jan;3(1):89-93. doi: 10.1038/nm0197-89. Nat Med. 1997. PMID: 8986748

10

Uridine recognition motifs of human equilibrative nucleoside transporters 1 and 2 produced in Saccharomyces cerevisiae.

Vickers MF, Zhang J, Visser F, Tackaberry T, Robins MJ, Nielsen LP, Nowak I, Baldwin SA, Young JD, Cass CE. Vickers MF, et al. Among authors: young jd. Nucleosides Nucleotides Nucleic Acids. 2004;23(1-2):361-73. doi: 10.1081/ncn-120028333. Nucleosides Nucleotides Nucleic Acids. 2004. PMID: 15043160

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