Kuchroo VK - Search Results

1

Reversal of NK-cell exhaustion in advanced melanoma by Tim-3 blockade.

da Silva IP, Gallois A, Jimenez-Baranda S, Khan S, Anderson AC, Kuchroo VK, Osman I, Bhardwaj N. da Silva IP, et al. Among authors: kuchroo vk. Cancer Immunol Res. 2014 May;2(5):410-22. doi: 10.1158/2326-6066.CIR-13-0171. Epub 2014 Feb 11. Cancer Immunol Res. 2014. PMID: 24795354 Free PMC article.

2

Tuning T cell activation threshold and effector function with cross-reactive peptide ligands.

Nicholson LB, Anderson AC, Kuchroo VK. Nicholson LB, et al. Among authors: kuchroo vk. Int Immunol. 2000 Feb;12(2):205-13. doi: 10.1093/intimm/12.2.205. Int Immunol. 2000. PMID: 10653856

3

The origin and regulation of autopathogenic T cells.

Anderson AC, Nicholson LB, Kuchroo VK. Anderson AC, et al. Among authors: kuchroo vk. J Clin Immunol. 2001 Mar;21(2):74-80. doi: 10.1023/a:1011027020890. J Clin Immunol. 2001. PMID: 11332656 Review.

4

T cell response in experimental autoimmune encephalomyelitis (EAE): role of self and cross-reactive antigens in shaping, tuning, and regulating the autopathogenic T cell repertoire.

Kuchroo VK, Anderson AC, Waldner H, Munder M, Bettelli E, Nicholson LB. Kuchroo VK, et al. Annu Rev Immunol. 2002;20:101-23. doi: 10.1146/annurev.immunol.20.081701.141316. Epub 2001 Oct 4. Annu Rev Immunol. 2002. PMID: 11861599 Review.

5

Expression of self-antigen in the thymus: a little goes a long way.

Anderson AC, Kuchroo VK. Anderson AC, et al. Among authors: kuchroo vk. J Exp Med. 2003 Dec 1;198(11):1627-9. doi: 10.1084/jem.20031803. J Exp Med. 2003. PMID: 14657216 Free PMC article. No abstract available.

6

IL-10 plays an important role in the homeostatic regulation of the autoreactive repertoire in naive mice.

Anderson AC, Reddy J, Nazareno R, Sobel RA, Nicholson LB, Kuchroo VK. Anderson AC, et al. Among authors: kuchroo vk. J Immunol. 2004 Jul 15;173(2):828-34. doi: 10.4049/jimmunol.173.2.828. J Immunol. 2004. PMID: 15240669

7

The Tim-3 ligand galectin-9 negatively regulates T helper type 1 immunity.

Zhu C, Anderson AC, Schubart A, Xiong H, Imitola J, Khoury SJ, Zheng XX, Strom TB, Kuchroo VK. Zhu C, et al. Among authors: kuchroo vk. Nat Immunol. 2005 Dec;6(12):1245-52. doi: 10.1038/ni1271. Epub 2005 Nov 13. Nat Immunol. 2005. PMID: 16286920

8

Tim protein structures reveal a unique face for ligand binding.

Anderson AC, Xiao S, Kuchroo VK. Anderson AC, et al. Among authors: kuchroo vk. Immunity. 2007 Mar;26(3):273-5. doi: 10.1016/j.immuni.2007.03.004. Immunity. 2007. PMID: 17376389 Free PMC article.

9

Differential engagement of Tim-1 during activation can positively or negatively costimulate T cell expansion and effector function.

Xiao S, Najafian N, Reddy J, Albin M, Zhu C, Jensen E, Imitola J, Korn T, Anderson AC, Zhang Z, Gutierrez C, Moll T, Sobel RA, Umetsu DT, Yagita H, Akiba H, Strom T, Sayegh MH, DeKruyff RH, Khoury SJ, Kuchroo VK. Xiao S, et al. Among authors: kuchroo vk. J Exp Med. 2007 Jul 9;204(7):1691-702. doi: 10.1084/jem.20062498. Epub 2007 Jul 2. J Exp Med. 2007. PMID: 17606630 Free PMC article.

10

Modulation of CD4 co-receptor limits spontaneous autoimmunity when high-affinity transgenic TCR specific for self-antigen is expressed on a genetically resistant background.

Illés Z, Waldner H, Reddy J, Anderson AC, Sobel RA, Kuchroo VK. Illés Z, et al. Among authors: kuchroo vk. Int Immunol. 2007 Oct;19(10):1235-48. doi: 10.1093/intimm/dxm094. Epub 2007 Sep 5. Int Immunol. 2007. PMID: 17804690

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