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Genome-wide interaction studies reveal sex-specific asthma risk alleles.
Myers RA, Scott NM, Gauderman WJ, Qiu W, Mathias RA, Romieu I, Levin AM, Pino-Yanes M, Graves PE, Villarreal AB, Beaty TH, Carey VJ, Croteau-Chonka DC, del Rio Navarro B, Edlund C, Hernandez-Cadena L, Navarro-Olivos E, Padhukasahasram B, Salam MT, Torgerson DG, Van den Berg DJ, Vora H, Bleecker ER, Meyers DA, Williams LK, Martinez FD, Burchard EG, Barnes KC, Gilliland FD, Weiss ST, London SJ, Raby BA, Ober C, Nicolae DL; GRAAD. Myers RA, et al. Among authors: qiu w. Hum Mol Genet. 2014 Oct 1;23(19):5251-9. doi: 10.1093/hmg/ddu222. Epub 2014 May 13. Hum Mol Genet. 2014. PMID: 24824216 Free PMC article.
Genetic control of gene expression at novel and established chronic obstructive pulmonary disease loci.
Castaldi PJ, Cho MH, Zhou X, Qiu W, Mcgeachie M, Celli B, Bakke P, Gulsvik A, Lomas DA, Crapo JD, Beaty TH, Rennard S, Harshfield B, Lange C, Singh D, Tal-Singer R, Riley JH, Quackenbush J, Raby BA, Carey VJ, Silverman EK, Hersh CP. Castaldi PJ, et al. Among authors: qiu w. Hum Mol Genet. 2015 Feb 15;24(4):1200-10. doi: 10.1093/hmg/ddu525. Epub 2014 Oct 14. Hum Mol Genet. 2015. PMID: 25315895 Free PMC article.
Gene Expression Profiling in Blood Provides Reproducible Molecular Insights into Asthma Control.
Croteau-Chonka DC, Qiu W, Martinez FD, Strunk RC, Lemanske RF Jr, Liu AH, Gilliland FD, Millstein J, Gauderman WJ, Ober C, Krishnan JA, White SR, Naureckas ET, Nicolae DL, Barnes KC, London SJ, Barraza-Villarreal A, Carey VJ, Weiss ST, Raby BA; Asthma BioRepository for Integrative Genomic Exploration (Asthma BRIDGE) Consortium. Croteau-Chonka DC, et al. Among authors: qiu w. Am J Respir Crit Care Med. 2017 Jan 15;195(2):179-188. doi: 10.1164/rccm.201601-0107OC. Am J Respir Crit Care Med. 2017. PMID: 27494826 Free PMC article.
Role of local CpG DNA methylation in mediating the 17q21 asthma susceptibility gasdermin B (GSDMB)/ORMDL sphingolipid biosynthesis regulator 3 (ORMDL3) expression quantitative trait locus.
Kothari PH, Qiu W, Croteau-Chonka DC, Martinez FD, Liu AH, Lemanske RF Jr, Ober C, Krishnan JA, Nicolae DL, Barnes KC, London SJ, Barraza-Villarreal A, White SR, Naureckas ET, Millstein J, Gauderman WJ, Gilliland FD, Carey VJ, Weiss ST, Raby BA; Asthma BioRepository for Integrative Genomic Exploration (Asthma BRIDGE) Consortium. Kothari PH, et al. Among authors: qiu w. J Allergy Clin Immunol. 2018 Jun;141(6):2282-2286.e6. doi: 10.1016/j.jaci.2017.11.057. Epub 2018 Jan 31. J Allergy Clin Immunol. 2018. PMID: 29374573 Free PMC article. No abstract available.
ITGB5 and AGFG1 variants are associated with severity of airway responsiveness.
Himes BE, Qiu W, Klanderman B, Ziniti J, Senter-Sylvia J, Szefler SJ, Lemanske RF Jr, Zeiger RS, Strunk RC, Martinez FD, Boushey H, Chinchilli VM, Israel E, Mauger D, Koppelman GH, Nieuwenhuis MA, Postma DS, Vonk JM, Rafaels N, Hansel NN, Barnes K, Raby B, Tantisira KG, Weiss ST. Himes BE, et al. Among authors: qiu w. BMC Med Genet. 2013 Aug 28;14:86. doi: 10.1186/1471-2350-14-86. BMC Med Genet. 2013. PMID: 23984888 Free PMC article.
Integrated genome-wide association, coexpression network, and expression single nucleotide polymorphism analysis identifies novel pathway in allergic rhinitis.
Bunyavanich S, Schadt EE, Himes BE, Lasky-Su J, Qiu W, Lazarus R, Ziniti JP, Cohain A, Linderman M, Torgerson DG, Eng CS, Pino-Yanes M, Padhukasahasram B, Yang JJ, Mathias RA, Beaty TH, Li X, Graves P, Romieu I, Navarro Bdel R, Salam MT, Vora H, Nicolae DL, Ober C, Martinez FD, Bleecker ER, Meyers DA, Gauderman WJ, Gilliland F, Burchard EG, Barnes KC, Williams LK, London SJ, Zhang B, Raby BA, Weiss ST. Bunyavanich S, et al. Among authors: qiu w. BMC Med Genomics. 2014 Aug 2;7:48. doi: 10.1186/1755-8794-7-48. BMC Med Genomics. 2014. PMID: 25085501 Free PMC article.
A disease module in the interactome explains disease heterogeneity, drug response and captures novel pathways and genes in asthma.
Sharma A, Menche J, Huang CC, Ort T, Zhou X, Kitsak M, Sahni N, Thibault D, Voung L, Guo F, Ghiassian SD, Gulbahce N, Baribaud F, Tocker J, Dobrin R, Barnathan E, Liu H, Panettieri RA Jr, Tantisira KG, Qiu W, Raby BA, Silverman EK, Vidal M, Weiss ST, Barabási AL. Sharma A, et al. Among authors: qiu w. Hum Mol Genet. 2015 Jun 1;24(11):3005-20. doi: 10.1093/hmg/ddv001. Epub 2015 Jan 12. Hum Mol Genet. 2015. PMID: 25586491 Free PMC article.
4,168 results