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Genomic and protein expression analysis reveals flap endonuclease 1 (FEN1) as a key biomarker in breast and ovarian cancer.
Abdel-Fatah TM, Russell R, Albarakati N, Maloney DJ, Dorjsuren D, Rueda OM, Moseley P, Mohan V, Sun H, Abbotts R, Mukherjee A, Agarwal D, Illuzzi JL, Jadhav A, Simeonov A, Ball G, Chan S, Caldas C, Ellis IO, Wilson DM 3rd, Madhusudan S. Abdel-Fatah TM, et al. Among authors: albarakati n. Mol Oncol. 2014 Oct;8(7):1326-38. doi: 10.1016/j.molonc.2014.04.009. Epub 2014 May 13. Mol Oncol. 2014. PMID: 24880630 Free PMC article.
Targeting XRCC1 deficiency in breast cancer for personalized therapy.
Sultana R, Abdel-Fatah T, Abbotts R, Hawkes C, Albarakati N, Seedhouse C, Ball G, Chan S, Rakha EA, Ellis IO, Madhusudan S. Sultana R, et al. Among authors: albarakati n. Cancer Res. 2013 Mar 1;73(5):1621-34. doi: 10.1158/0008-5472.CAN-12-2929. Epub 2012 Dec 19. Cancer Res. 2013. PMID: 23253910
Single-strand selective monofunctional uracil-DNA glycosylase (SMUG1) deficiency is linked to aggressive breast cancer and predicts response to adjuvant therapy.
Abdel-Fatah TM, Albarakati N, Bowell L, Agarwal D, Moseley P, Hawkes C, Ball G, Chan S, Ellis IO, Madhusudan S. Abdel-Fatah TM, et al. Among authors: albarakati n. Breast Cancer Res Treat. 2013 Dec;142(3):515-27. doi: 10.1007/s10549-013-2769-6. Epub 2013 Nov 20. Breast Cancer Res Treat. 2013. PMID: 24253812
DNA polymerase β deficiency is linked to aggressive breast cancer: a comprehensive analysis of gene copy number, mRNA and protein expression in multiple cohorts.
Abdel-Fatah TM, Russell R, Agarwal D, Moseley P, Abayomi MA, Perry C, Albarakati N, Ball G, Chan S, Caldas C, Ellis IO, Madhusudan S. Abdel-Fatah TM, et al. Among authors: albarakati n. Mol Oncol. 2014 May;8(3):520-32. doi: 10.1016/j.molonc.2014.01.001. Epub 2014 Jan 10. Mol Oncol. 2014. PMID: 24462520 Free PMC article.
SUMOylation proteins in breast cancer.
Alshareeda AT, Negm OH, Green AR, Nolan C, Tighe P, Albarakati N, Sultana R, Madhusudan S, Ellis IO, Rakha EA. Alshareeda AT, et al. Among authors: albarakati n. Breast Cancer Res Treat. 2014 Apr;144(3):519-30. doi: 10.1007/s10549-014-2897-7. Epub 2014 Mar 1. Breast Cancer Res Treat. 2014. PMID: 24584753
Targeting BRCA1-BER deficient breast cancer by ATM or DNA-PKcs blockade either alone or in combination with cisplatin for personalized therapy.
Albarakati N, Abdel-Fatah TM, Doherty R, Russell R, Agarwal D, Moseley P, Perry C, Arora A, Alsubhi N, Seedhouse C, Rakha EA, Green A, Ball G, Chan S, Caldas C, Ellis IO, Madhusudan S. Albarakati N, et al. Mol Oncol. 2015 Jan;9(1):204-17. doi: 10.1016/j.molonc.2014.08.001. Epub 2014 Aug 27. Mol Oncol. 2015. PMID: 25205036 Free PMC article. Clinical Trial.
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