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Colon cancer-derived oncogenic EGFR G724S mutant identified by whole genome sequence analysis is dependent on asymmetric dimerization and sensitive to cetuximab.
Cho J, Bass AJ, Lawrence MS, Cibulskis K, Cho A, Lee SN, Yamauchi M, Wagle N, Pochanard P, Kim N, Park AK, Won J, Hur HS, Greulich H, Ogino S, Sougnez C, Voet D, Tabernero J, Jimenez J, Baselga J, Gabriel SB, Lander ES, Getz G, Eck MJ, Park WY, Meyerson M. Cho J, et al. Among authors: park ak, park wy. Mol Cancer. 2014 Jun 4;13:141. doi: 10.1186/1476-4598-13-141. Mol Cancer. 2014. PMID: 24894453 Free PMC article.
The somatic genomic landscape of chromophobe renal cell carcinoma.
Davis CF, Ricketts CJ, Wang M, Yang L, Cherniack AD, Shen H, Buhay C, Kang H, Kim SC, Fahey CC, Hacker KE, Bhanot G, Gordenin DA, Chu A, Gunaratne PH, Biehl M, Seth S, Kaipparettu BA, Bristow CA, Donehower LA, Wallen EM, Smith AB, Tickoo SK, Tamboli P, Reuter V, Schmidt LS, Hsieh JJ, Choueiri TK, Hakimi AA; The Cancer Genome Atlas Research Network; Chin L, Meyerson M, Kucherlapati R, Park WY, Robertson AG, Laird PW, Henske EP, Kwiatkowski DJ, Park PJ, Morgan M, Shuch B, Muzny D, Wheeler DA, Linehan WM, Gibbs RA, Rathmell WK, Creighton CJ. Davis CF, et al. Among authors: park pj, park wy. Cancer Cell. 2014 Sep 8;26(3):319-330. doi: 10.1016/j.ccr.2014.07.014. Epub 2014 Aug 21. Cancer Cell. 2014. PMID: 25155756 Free PMC article.
Structure and mechanism of activity-based inhibition of the EGF receptor by Mig6.
Park E, Kim N, Ficarro SB, Zhang Y, Lee BI, Cho A, Kim K, Park AKJ, Park WY, Murray B, Meyerson M, Beroukhim R, Marto JA, Cho J, Eck MJ. Park E, et al. Among authors: park akj, park wy. Nat Struct Mol Biol. 2015 Sep;22(9):703-711. doi: 10.1038/nsmb.3074. Epub 2015 Aug 17. Nat Struct Mol Biol. 2015. PMID: 26280531 Free PMC article.
Integrated genomic approaches identify upregulation of SCRN1 as a novel mechanism associated with acquired resistance to erlotinib in PC9 cells harboring oncogenic EGFR mutation.
Kim N, Cho A, Watanabe H, Choi YL, Aziz M, Kassner M, Joung JG, Park AK, Francis JM, Bae JS, Ahn SM, Kim KM, Park JO, Park WY, Ahn MJ, Park K, Koo J, Yin HH, Cho J. Kim N, et al. Among authors: park ak, park jo, park k, park wy. Oncotarget. 2016 Mar 22;7(12):13797-809. doi: 10.18632/oncotarget.7318. Oncotarget. 2016. PMID: 26883194 Free PMC article.
Comprehensive somatic genome alterations of urachal carcinoma.
Lee S, Lee J, Sim SH, Lee Y, Moon KC, Lee C, Park WY, Kim NK, Lee SH, Lee H. Lee S, et al. Among authors: park wy. J Med Genet. 2017 Aug;54(8):572-578. doi: 10.1136/jmedgenet-2016-104390. Epub 2017 Mar 27. J Med Genet. 2017. PMID: 28348108
679 results