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Page 1
Discovery of a Potent, S1P3-Sparing Benzothiazole Agonist of Sphingosine-1-Phosphate Receptor 1 (S1P1).
Lanman BA, Cee VJ, Cheruku SR, Frohn M, Golden J, Lin J, Lobera M, Marantz Y, Muller KM, Neira SC, Pickrell AJ, Rivenzon-Segal D, Schutz N, Sharadendu A, Yu X, Zhang Z, Buys J, Fiorino M, Gore A, Horner M, Itano A, McElvain M, Middleton S, Schrag M, Vargas HM, Xu H, Xu Y, Zhang X, Siu J, Bürli RW. Lanman BA, et al. Among authors: marantz y. ACS Med Chem Lett. 2010 Nov 9;2(2):102-6. doi: 10.1021/ml100228m. eCollection 2011 Feb 10. ACS Med Chem Lett. 2010. PMID: 24900287 Free PMC article.
Benzofuran Derivatives as Potent, Orally Active S1P1 Receptor Agonists: A Preclinical Lead Molecule for MS.
Saha AK, Yu X, Lin J, Lobera M, Sharadendu A, Chereku S, Schutz N, Segal D, Marantz Y, McCauley D, Middleton S, Siu J, Bürli RW, Buys J, Horner M, Salyers K, Schrag M, Vargas HM, Xu Y, McElvain M, Xu H. Saha AK, et al. Among authors: marantz y. ACS Med Chem Lett. 2010 Nov 9;2(2):97-101. doi: 10.1021/ml100227q. eCollection 2011 Feb 10. ACS Med Chem Lett. 2010. PMID: 24900286 Free PMC article.
G protein coupled receptors -in silico drug discovery and design.
Sela I, Golan G, Strajbl M, Rivenzon-Segal D, Bar-Haim S, Bloch I, Inbal B, Shitrit A, Ben-Zeev E, Fichman M, Markus Y, Marantz Y, Senderowitz H, Kalid O. Sela I, et al. Among authors: marantz y. Curr Top Med Chem. 2010;10(6):638-56. doi: 10.2174/156802610791111498. Curr Top Med Chem. 2010. PMID: 20337589 Review.
Small molecule correctors of F508del-CFTR discovered by structure-based virtual screening.
Kalid O, Mense M, Fischman S, Shitrit A, Bihler H, Ben-Zeev E, Schutz N, Pedemonte N, Thomas PJ, Bridges RJ, Wetmore DR, Marantz Y, Senderowitz H. Kalid O, et al. Among authors: marantz y. J Comput Aided Mol Des. 2010 Dec;24(12):971-91. doi: 10.1007/s10822-010-9390-0. Epub 2010 Oct 26. J Comput Aided Mol Des. 2010. PMID: 20976528 Free PMC article.
G protein-coupled receptors: in silico drug discovery in 3D.
Becker OM, Marantz Y, Shacham S, Inbal B, Heifetz A, Kalid O, Bar-Haim S, Warshaviak D, Fichman M, Noiman S. Becker OM, et al. Among authors: marantz y. Proc Natl Acad Sci U S A. 2004 Aug 3;101(31):11304-9. doi: 10.1073/pnas.0401862101. Epub 2004 Jul 26. Proc Natl Acad Sci U S A. 2004. PMID: 15277683 Free PMC article.
PREDICT modeling and in-silico screening for G-protein coupled receptors.
Shacham S, Marantz Y, Bar-Haim S, Kalid O, Warshaviak D, Avisar N, Inbal B, Heifetz A, Fichman M, Topf M, Naor Z, Noiman S, Becker OM. Shacham S, et al. Among authors: marantz y. Proteins. 2004 Oct 1;57(1):51-86. doi: 10.1002/prot.20195. Proteins. 2004. PMID: 15326594
Modeling the 3D structure of GPCRs from sequence.
Shacham S, Topf M, Avisar N, Glaser F, Marantz Y, Bar-Haim S, Noiman S, Naor Z, Becker OM. Shacham S, et al. Among authors: marantz y. Med Res Rev. 2001 Sep;21(5):472-83. doi: 10.1002/med.1019. Med Res Rev. 2001. PMID: 11579443 Review.
VRX-03011, a novel 5-HT4 agonist, enhances memory and hippocampal acetylcholine efflux.
Mohler EG, Shacham S, Noiman S, Lezoualc'h F, Robert S, Gastineau M, Rutkowski J, Marantz Y, Dumuis A, Bockaert J, Gold PE, Ragozzino ME. Mohler EG, et al. Among authors: marantz y. Neuropharmacology. 2007 Sep;53(4):563-73. doi: 10.1016/j.neuropharm.2007.06.016. Epub 2007 Jun 30. Neuropharmacology. 2007. PMID: 17692343
19 results