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Discovery and in Vivo Evaluation of Potent Dual CYP11B2 (Aldosterone Synthase) and CYP11B1 Inhibitors.
Meredith EL, Ksander G, Monovich LG, Papillon JP, Liu Q, Miranda K, Morris P, Rao C, Burgis R, Capparelli M, Hu QY, Singh A, Rigel DF, Jeng AY, Beil M, Fu F, Hu CW, LaSala D. Meredith EL, et al. Among authors: singh a. ACS Med Chem Lett. 2013 Oct 17;4(12):1203-7. doi: 10.1021/ml400324c. eCollection 2013 Dec 12. ACS Med Chem Lett. 2013. PMID: 24900631 Free PMC article.
Structure-Activity Relationships, Pharmacokinetics, and in Vivo Activity of CYP11B2 and CYP11B1 Inhibitors.
Papillon JP, Adams CM, Hu QY, Lou C, Singh AK, Zhang C, Carvalho J, Rajan S, Amaral A, Beil ME, Fu F, Gangl E, Hu CW, Jeng AY, LaSala D, Liang G, Logman M, Maniara WM, Rigel DF, Smith SA, Ksander GM. Papillon JP, et al. Among authors: singh ak. J Med Chem. 2015 Jun 11;58(11):4749-70. doi: 10.1021/acs.jmedchem.5b00407. Epub 2015 May 21. J Med Chem. 2015. PMID: 25953419
Discovery of N-[5-(6-Chloro-3-cyano-1-methyl-1H-indol-2-yl)-pyridin-3-ylmethyl]-ethanesulfonamide, a Cortisol-Sparing CYP11B2 Inhibitor that Lowers Aldosterone in Human Subjects.
Papillon JP, Lou C, Singh AK, Adams CM, Ksander GM, Beil ME, Chen W, Leung-Chu J, Fu F, Gan L, Hu CW, Jeng AY, LaSala D, Liang G, Rigel DF, Russell KS, Vest JA, Watson C. Papillon JP, et al. Among authors: singh ak. J Med Chem. 2015 Dec 10;58(23):9382-94. doi: 10.1021/acs.jmedchem.5b01545. Epub 2015 Nov 18. J Med Chem. 2015. PMID: 26540564
Synthetic phospholipids as specific substrates for plasma endothelial lipase.
Papillon JP, Pan M, Brousseau ME, Gilchrist MA, Lou C, Singh AK, Stawicki T, Thompson JE. Papillon JP, et al. Among authors: singh ak. Bioorg Med Chem Lett. 2016 Aug 1;26(15):3514-7. doi: 10.1016/j.bmcl.2016.06.032. Epub 2016 Jun 14. Bioorg Med Chem Lett. 2016. PMID: 27344207
Prevalence of Diabetes Mellitus among Haitian Americans: A Hidden Epidemic.
Bivins B, Rodney T, Bivins MH, Ruffin L, Eliezer CP, Lestage-Laforest M, Owusu B, Baptiste D, Cineas N, Duroseau B, Bivins P, Singh A. Bivins B, et al. Among authors: singh a. J Health Care Poor Underserved. 2024;35(2):605-618. J Health Care Poor Underserved. 2024. PMID: 38828584
Glass door injury: A preventable public health problem.
Bhattacharya S, Singh A, Kumar V, Raj V, Grover A, Jahnavi G, Garg S. Bhattacharya S, et al. Among authors: singh a. J Family Med Prim Care. 2024 Apr;13(4):1584-1585. doi: 10.4103/jfmpc.jfmpc_923_23. Epub 2024 Apr 22. J Family Med Prim Care. 2024. PMID: 38827694 Free PMC article. No abstract available.
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