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Discovery of BAF312 (Siponimod), a Potent and Selective S1P Receptor Modulator.
Pan S, Gray NS, Gao W, Mi Y, Fan Y, Wang X, Tuntland T, Che J, Lefebvre S, Chen Y, Chu A, Hinterding K, Gardin A, End P, Heining P, Bruns C, Cooke NG, Nuesslein-Hildesheim B. Pan S, et al. Among authors: chu a. ACS Med Chem Lett. 2013 Jan 4;4(3):333-7. doi: 10.1021/ml300396r. eCollection 2013 Mar 14. ACS Med Chem Lett. 2013. PMID: 24900670 Free PMC article.
A monoselective sphingosine-1-phosphate receptor-1 agonist prevents allograft rejection in a stringent rat heart transplantation model.
Pan S, Mi Y, Pally C, Beerli C, Chen A, Guerini D, Hinterding K, Nuesslein-Hildesheim B, Tuntland T, Lefebvre S, Liu Y, Gao W, Chu A, Brinkmann V, Bruns C, Streiff M, Cannet C, Cooke N, Gray N. Pan S, et al. Among authors: chu a. Chem Biol. 2006 Nov;13(11):1227-34. doi: 10.1016/j.chembiol.2006.09.017. Chem Biol. 2006. PMID: 17114004
Nidufexor (LMB763), a Novel FXR Modulator for the Treatment of Nonalcoholic Steatohepatitis.
Chianelli D, Rucker PV, Roland J, Tully DC, Nelson J, Liu X, Bursulaya B, Hernandez ED, Wu J, Prashad M, Schlama T, Liu Y, Chu A, Schmeits J, Huang DJ, Hill R, Bao D, Zoll J, Kim Y, Groessl T, McNamara P, Liu B, Richmond W, Sancho-Martinez I, Phimister A, Seidel HM, Badman MK, Joseph SB, Laffitte B, Molteni V. Chianelli D, et al. Among authors: chu a. J Med Chem. 2020 Apr 23;63(8):3868-3880. doi: 10.1021/acs.jmedchem.9b01621. Epub 2020 Feb 5. J Med Chem. 2020. PMID: 31940200
A fear conditioned cue orchestrates a suite of behaviors in rats.
Chu A, Gordon NT, DuBois AM, Michel CB, Hanrahan KE, Williams DC, Anzellotti S, McDannald MA. Chu A, et al. Elife. 2024 May 21;13:e82497. doi: 10.7554/eLife.82497. Online ahead of print. Elife. 2024. PMID: 38770736 Free article.
Programmatic implementation of depression screening and remote mental health support sessions for persons recently diagnosed with TB in Lima, Peru during the COVID-19 pandemic.
Contreras C, Cruz JS, Galea JT, Chu AL, Puma D, Ramos L, Tovar M, Peinado J, Lecca L, Keshavjee S, Yuen CM, Raviola G. Contreras C, et al. Among authors: chu al. Glob Ment Health (Camb). 2024 Apr 4;11:e59. doi: 10.1017/gmh.2024.21. eCollection 2024. Glob Ment Health (Camb). 2024. PMID: 38751725 Free PMC article.
1,631 results