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Pharmacologic profile of the Adnectin BMS-962476, a small protein biologic alternative to PCSK9 antibodies for low-density lipoprotein lowering.
Mitchell T, Chao G, Sitkoff D, Lo F, Monshizadegan H, Meyers D, Low S, Russo K, DiBella R, Denhez F, Gao M, Myers J, Duke G, Witmer M, Miao B, Ho SP, Khan J, Parker RA. Mitchell T, et al. Among authors: ho sp. J Pharmacol Exp Ther. 2014 Aug;350(2):412-24. doi: 10.1124/jpet.114.214221. Epub 2014 Jun 10. J Pharmacol Exp Ther. 2014. PMID: 24917546
Loss of Function of GALNT2 Lowers High-Density Lipoproteins in Humans, Nonhuman Primates, and Rodents.
Khetarpal SA, Schjoldager KT, Christoffersen C, Raghavan A, Edmondson AC, Reutter HM, Ahmed B, Ouazzani R, Peloso GM, Vitali C, Zhao W, Somasundara AV, Millar JS, Park Y, Fernando G, Livanov V, Choi S, Noé E, Patel P, Ho SP; Myocardial Infarction Exome Sequencing Study; Kirchgessner TG, Wandall HH, Hansen L, Bennett EP, Vakhrushev SY, Saleheen D, Kathiresan S, Brown CD, Abou Jamra R, LeGuern E, Clausen H, Rader DJ. Khetarpal SA, et al. Among authors: ho sp. Cell Metab. 2016 Aug 9;24(2):234-45. doi: 10.1016/j.cmet.2016.07.012. Cell Metab. 2016. PMID: 27508872 Free PMC article.
Fungi and bacteria occupy distinct spatial niches within carious dentin.
Sulyanto RM, Beall CJ, Ha K, Montesano J, Juang J, Dickson JR, Hashmi SB, Bradbury S, Leys EJ, Edgerton M, Ho SP, Griffen AL. Sulyanto RM, et al. PLoS Pathog. 2024 May 28;20(5):e1011865. doi: 10.1371/journal.ppat.1011865. Online ahead of print. PLoS Pathog. 2024. PMID: 38805482 Free article.
2D Materials Kill Bacteria from Within.
Hou D, Zhou S, Tan X, Yuan D, Yan J, Zeng Q, Chen Y. Hou D, et al. Nano Lett. 2024 May 24. doi: 10.1021/acs.nanolett.4c00803. Online ahead of print. Nano Lett. 2024. PMID: 38789389
A new two-dimensional, spiropyran-based polymer fluorescent nanoprobe with quantitative-fluorescent and photochromic properties for multi-substance detection.
Lin R, Zhang H, Huang Y. Lin R, et al. Nanotechnology. 2024 May 22. doi: 10.1088/1361-6528/ad4ee6. Online ahead of print. Nanotechnology. 2024. PMID: 38776878
Herein a new polymer fluorescent nanoprobe (2DSP-C28) has been synthesized, by adopting a two-dimensional (2D), spiropyran (SP)-based nanosheet structure with hydrophobic long-chain alkanes (C28). Unlike a traditional spiropyran-based small molecule probe, the 2DSP- …
Herein a new polymer fluorescent nanoprobe (2DSP-C28) has been synthesized, by adopting a two-dimensional (2D), spiropyran (SP)-based …
Photoisomerization of Spiropyran in Solution: A Surface Hopping Investigation.
Frassi D, Padula G, Granucci G. Frassi D, et al. J Phys Chem B. 2024 May 30;128(21):5246-5253. doi: 10.1021/acs.jpcb.4c00778. Epub 2024 May 17. J Phys Chem B. 2024. PMID: 38760327
We performed a computational investigation of the photoisomerization of an unsubstituted spiropyran in solution using surface hopping molecular dynamics simulations in a semiempirical framework. ...
We performed a computational investigation of the photoisomerization of an unsubstituted spiropyran in solution using surface hopping …
"Dissolve-on-Demand" 3D Printed Materials: Polymerizable Eutectics for Generating High Modulus, Thermoresponsive and Photoswitchable Eutectogels.
Mutch AL, Nahar Y, Bissember AC, Corrigan N, Boyer C, Oh XY, Truong VX, Thickett SC. Mutch AL, et al. Macromol Rapid Commun. 2024 May 13:e2400268. doi: 10.1002/marc.202400268. Online ahead of print. Macromol Rapid Commun. 2024. PMID: 38739444
The versatility of these PE systems is demonstrated through the addition of a photoswitchable spiropyran acrylate monomer, as well as applying the PE formulation as a stereolithography (SLA)-based 3D printing resin. ...
The versatility of these PE systems is demonstrated through the addition of a photoswitchable spiropyran acrylate monomer, as well as …
Ion-Cross-Linked Hybrid Photochromic Hydrogels with Enhanced Mechanical Properties and Shape Memory Behaviour.
Long S, Chen F, Ren H, Hu Y, Chen C, Huang Y, Li X. Long S, et al. Polymers (Basel). 2024 Apr 10;16(8):1031. doi: 10.3390/polym16081031. Polymers (Basel). 2024. PMID: 38674950 Free PMC article.
A novel shape-shifting photochromic hydrogel system was designed and fabricated by embedding hydrophobic spiropyran (SP) into double polymeric network (DN) through micellar copolymerisation. Here, sodium alginate (Alg) and poly acrylate-co-methyl acrylate-co-spiropyran …
A novel shape-shifting photochromic hydrogel system was designed and fabricated by embedding hydrophobic spiropyran (SP) into double …
Fluorescence Switching and Photoisomerization of a Spiropyran Molecular Photoswitch through Confined Spaces Regulation in Crystals.
Wang X, Yu H, Yang R, Li B, Wang M, Xu B, Tian W. Wang X, et al. J Phys Chem Lett. 2024 Apr 18;15(15):4224-4228. doi: 10.1021/acs.jpclett.4c00397. Epub 2024 Apr 11. J Phys Chem Lett. 2024. PMID: 38602419
Spiropyran (SP) and its derivatives are highly attractive owing to their distinctive merits in high contrast and fast response read-out systems. ...
Spiropyran (SP) and its derivatives are highly attractive owing to their distinctive merits in high contrast and fast response read-o …
1,053 results